Surgery

Article Surgery

Pull-Through for Hirschsprung's Disease: Insights for Limited-Resource Settings From Mbarara

Felix Oyania, Meera Kotagal, Anne Shikanda Wesonga, Stella Alice Nimanya, Martin Situma

Summary: Through this small case series study, we have demonstrated that pull-through with simultaneous stoma closure can be safely performed in resource-constrained settings, potentially reducing the treatment approach from three stages to two.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

Roles for Bile Acid Signaling and Nonsense-Mediated Ribonucleic Acid Decay in Small Bowel Resection-Associated Liver Injury

Maria E. Tecos, Allie E. Steinberger, Jun Guo, Deborah C. Rubin, Nicholas O. Davidson, Brad W. Warner

Summary: This study suggests that ileocecal resection can interrupt the enterohepatic circulation, reducing the liver's exposure to toxic and inflammatory mediators and promoting physiological adaptations in bile acid metabolism while maintaining existing homeostatic pathways.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

Chart-Derived Frailty Index and 90-Day Mortality After Burn Surgery

Jihion Yu, Yu-Gyeong Kong, Jun -Young Park, Hee Yeong Kim, Miyoung Kwon, Yun Jae Han, Narae Lee, Young Joo Seo, Young-Kug Kim

Summary: High preoperative chart-derived frailty index (CFI) is associated with increased 90-day mortality, major adverse cardiac events, pneumonia, continuous renal replacement therapy requirement, and prolonged ICU stay following burn surgery.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

Insurance Not Socioeconomic Status is Associated With Access to Postacute Care After Injury: A Multicenter Cohort Study

Anthony Gebran, Mohamad El Moheb, Juan P. Herrera-Escobar, Jefferson A. Proano-Zamudio, Lydia R. Maurer, Taylor E. Lamarre, Savo Bou Zein Eddine, Sabrina E. Sanchez, Deepika Nehra, Ali Salim, George C. Velmahos, Haytham M. A. Kaafarani

Summary: This study examines the association between insurance type, socioeconomic status (SES), and postacute care utilization after injury. It finds that insurance status, particularly having Medicaid, can be a barrier to accessing postacute care services. Initiatives to reduce these access disparities are necessary.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

There's No Place Like Home: Delirium as a Barrier in Geriatric Trauma

Abdoulaziz Toure, Roshan Tadi, Mitchell Meagher, Catherine Ting Brown, Hoi Lam, Samantha LaRosa, Launick Saint-Fort, Huda Syed, Nathaniel Harshaw, Katherine Moore, Neelofer Sohail, Lindsey L. Perea

Summary: This study aims to identify predictive factors of delirium in geriatric trauma patients and found that early controlled substance use, urinary tract infection, and extended intensive care unit length of stay are significantly associated with delirium.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

The Use of Inflammatory Markers for Treatment Response Monitoring in Acute Cholangitis: A Retrospective Cohort Study

Andrei M. Belyaev, Phillip Thwaite, Jeremy Rossaak, Jonathan Chen, Barnaby Smith

Summary: This study compared the discriminatory powers of traditional blood inflammatory markers and proposed new inflammatory markers to monitor treatment response in patients with acute cholangitis. The results showed that the new inflammatory markers had better ability to distinguish between patients with and without biliary tract infection.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

Reconsidering the Role of Frozen Section in Sentinel Lymph Node Biopsy for Mastectomy Patients

Mawin Vongsaisuwon, Voranaddha Vacharathit, Bhoowit Lerttiendamrong, Sopark Manasnayakorn, Kasaya Tantiphlachiva, Phuphat Vongwattanakit, Nattanan Treeratanapun

Summary: This pilot study conducted in Thailand aimed to evaluate the role of intraoperative frozen section of sentinel lymph node biopsy in early-stage breast cancer patients who underwent mastectomy. The results showed that using permanent section analysis alone for lymph node biopsy may not lower the standard of care, while reducing operation costs, operative time, and anesthetic side effects.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

Decreased Glycocalyx Shedding on Presentation in Hemorrhaging Geriatric Trauma Patients

Tanya Anand, Anna E. Crawford, Michael Sjoquist, Zain G. Hashmi, Robert P. Richter, Bellal Joseph, Jillian R. Richter

Summary: This study compared the shedding of Sdc1 between older adults and younger adults and explored the regulators associated with EG shedding.

JOURNAL OF SURGICAL RESEARCH (2024)

Review Oncology

Impact of thoracic duct resection during radical esophagectomy on oncological and survival outcomes: Systematic review

Harry Farrow, Oliver J. Pickering, James A. Gossage, Philip H. Pucher

Summary: The inclusion or exclusion of the thoracic duct in radical esophagectomy for esophageal cancer is a controversial issue. While removing the thoracic duct may increase lymph node yield, it may also lead to higher morbidity without any survival benefit.
Article Clinical Neurology

Pediatric Neurostimulation and Practice Evolution

Saadi Ghatan

Summary: Pediatric epilepsy surgery has gained recognition for its safety and effectiveness in treating epilepsy in children. Advances in diagnostic and treatment techniques, such as minimally invasive procedures and neuroimaging, have contributed to its rapid growth potential.

NEUROSURGERY CLINICS OF NORTH AMERICA (2024)

Article Oncology

Overview of Current Hepatocellular Carcinoma Staging Systems Is There an Optimal System?

Mariana Chavez-Villa, Ismael Dominguez-Rosado

Summary: Over the past 40 years, multiple staging systems have been developed for hepatocellular carcinoma (HCC) to guide treatment and determine prognosis. However, the heterogeneity of HCC and advances in diagnostic and therapeutic tools have made staging algorithms and eligibility criteria more complex. Recent advances in neoadjuvant therapy, downstaging, and adjuvant therapy have challenged traditional paradigms but also raised new questions. Although there is no perfect or universal staging system yet, models will continue to be refined as evidence advances. Individualized decision making and multidisciplinary approaches will play key roles in the management of HCC.

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA (2024)

Letter Surgery

Correspondence and Communications Sternal bone anatomy on preoperative imaging as an independent predictor of deep sternal dehiscence following median sternotomy

Emmeline Jia, Monica Morgenstern, Sivana Barron, Amy Chen, Shannon R. Garvey, John B. Park, Benjamin Rahmani, Oluwaseun D. Adebagbo, Josephine Nwokedi, Louis Chu, Ryan P. Cauley

Summary: Complications following median sternotomy are a concern. Plastic surgeons are being consulted to close complex sternotomy wounds, thus a more accurate risk stratification tool is needed. This study examines the association of preoperative radiologic sternal measurements and deep sternal dehiscence, finding that decreased manubrium sternal thickness and absolute inferior sternal width are significantly associated with deep sternal dehiscence.

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY (2024)

Article Orthopedics

Establishing patient-centered metrics for the knee injury and osteoarthritis outcome score following medial unicompartmental knee arthropalsty

Ignacio Pasqualini, Michael Mariorenzi, Alison K. Klika, Pedro J. Rullan, Chao Zhang, Trevor G. Murray, Robert M. Molloy, Nicolas S. Piuzzi

Summary: This study aimed to determine the minimal clinically important difference (MCID) and the patient acceptable symptoms state (PASS) threshold for the knee injury and osteoarthritis outcome score (KOOS) pain subscore, KOOS physical short form (PS), and KOOS joint replacement (JR) following medial unicompartmental knee arthroplasty (mUKA). The study identified useful values for the MCID and PASS thresholds at 1 year following medial UKA of KOOS pain, KOOS PS, and KOOS JR scores. These values may be used as targets for surgeons when evaluating PROMS using KOOS to determine whether patients have achieved successful outcomes after their surgical intervention.
Article Surgery

Colleges and CrimedComparing Homicide and Suicide Rates Among College Towns and Their Counterparts

Carter M. Prentice, Jamie Song, Michelle Degli Esposti, Jonathan Jay, Douglas J. Wiebe, Christina L. Jacovides, Mark J. Seamon, Elinore J. Kaufman

Summary: This study investigates differences in homicide and suicide rates between college towns and other areas. It found that college towns have lower firearm suicide rates, especially among younger individuals. However, individuals under the age of 18 have an increased risk of homicide and suicide in college towns.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

Recovery Services for Interpersonal Violence Victims on Healthcare Use at a Trauma Center

Kristie J. Sun, Kevin Y. Zhu, Tyler J. Moon, Mary A. Breslin, Vanessa P. Ho, Heather A. Vallier

Summary: This study describes the utilization and outcomes of Trauma Recovery Services (TRS) for interpersonal violence (IPV) patients. The study found that patients who used TRS had longer hospital stays, more emergency department visits, and frequent outpatient visits. Utilization of food and housing services was associated with hospital stay, emergency department visits, and outpatient visits.

JOURNAL OF SURGICAL RESEARCH (2024)

Article Surgery

Humanized Anti-Carcinoembryonic Antigen Antibodies Brightly Target and Label Gastric Cancer in Orthotopic Mouse Models

Kristin E. Cox, Michael A. Turner, Siamak Amirfakhri, Thinzar M. Lavin, Mojgan Hosseini, Pradipta Ghosh, Marygorret Obonyo, Takashi Murakami, Robert M. Hoffman, Paul J. Yazaki, Michael Bouvet

Summary: This study demonstrates the potential of using humanized anti-carcinoembryonic antigen (CEA) antibodies conjugated with near-infrared dyes to specifically label gastric cancers in mouse models. Orthotopic models showed bright and specific labeling with more than ten times higher tumor-to-background ratios compared to the control. This tumor-specific fluorescent antibody has promising potential as a clinical tool for improving visualization of gastric cancer margins during surgical resection.

JOURNAL OF SURGICAL RESEARCH (2024)

Editorial Material Clinical Neurology

Endoscopic Trans-Sphenoidal Resection of a Giant Pituitary Neuroendocrine Tumor with Third Ventricle Invasion and Obstructive Hydrocephalus: Surgical Anatomy and Two-Dimensional Operative Video

Beatrice C. Bono, Davide Milani, Fabio Ferreli, Simone Olei, Luca Raspagliesi, Maria Pia Tropeano, Giovanni B. Lasio, Federico Pessina

WORLD NEUROSURGERY (2024)

Review Clinical Neurology

Systematic Reviews and Meta-Analyses in Pediatric Neurosurgery: Essential Domains for a Pediatric Neurosurgeon

Victor M. Lu

Summary: This review emphasizes four essential domains that should be considered when interpreting pediatric neurosurgical SRMAs and provides examples to ensure accurate and effective interpretation of findings in this niche.

WORLD NEUROSURGERY (2024)

Review Clinical Neurology

Modic Changes Increase the Cage Subsidence Rate in Spinal Interbody Fusion Surgery: A Systematic Review and Network Meta-Analysis

Yuchen Duan, Dagang Feng, Min Zhu, Heng Qiu, Tong Li, Zhen Chen, Leiming Jiang, Yong Huang

Summary: This study aimed to compare the effect of different Modic changes (MC) grades on the cage subsidence rate after spinal interbody fusion surgery. A meta-analysis was conducted on relevant randomized controlled trials and cohort studies. The results showed that MC may be associated with a higher cage subsidence rate. With the increase in MC grades, the incidence of subsidence decreased gradually, but it was always higher than that in the non-Modic changes (NMC). Oblique lumbar interbody fusion may be a better treatment choice for lumbar degenerative disease with MC.

WORLD NEUROSURGERY (2024)

Letter Oncology

Pancreatic cancer care: Lighting the way with the torch of staging laparoscopy and advanced imaging

Michele Fiore, Gian Marco Petrianni, Gabriele D'Ercole, Pasquale Trecca, Sara Ramella