Surgery

Article Surgery

Evaluation of International Contemporary Operative Outcomes and Management Trends Associated With Esophagectomy: A 4-Year Study of >6000 Patients Using ECCG Definitions and the Online Esodata Database

Madhan K. Kuppusamy, Donald E. Low

Summary: This study verifies the utility of international online datasets in benchmarking and monitoring treatment and outcomes in major oncologic procedures. It utilizes the Esodata database to update contemporary outcomes and monitor trends in practice. The results show an increase in the use of minimally invasive approaches for esophagectomy, a high percentage of complications, improvements in pneumonia and key quality metrics, but with an anastomotic leak rate still above 10%.

ANNALS OF SURGERY (2022)

Article Surgery

Changing trends in mortality among solid organ transplant recipients hospitalized for COVID-19 during the course of the pandemic

Madeleine R. Heldman, Olivia S. Kates, Kassem Safa, Camille N. Kotton, Sarah J. Georgia, Julie M. Steinbrink, Barbara D. Alexander, Marion Hemmersbach-Miller, Emily A. Blumberg, Ashrit Multani, Brandy Haydel, Ricardo M. La Hoz, Lisset Moni, Yesabeli Condor, Sandra Flores, Carlos G. Munoz, Juan Guitierrez, Esther I. Diaz, Daniela Diaz, Rodrigo Vianna, Giselle Guerra, Matthias Loebe, Robert M. Rakita, Maricar Malinis, Marwan M. Azar, Vagish Hemmige, Margaret E. McCort, Zohra S. Chaudhry, Pooja P. Singh, Kailey Hughes Kramer, Arzu Velioglu, Julie M. Yabu, Jose A. Morillis, Sapna A. Mehta, Sajal D. Tanna, Michael G. Ison, Ariella C. Derenge, David van Duin, Adrienne Maximin, Carlene Gilbert, Jason D. Goldman, Erika D. Lease, Cynthia E. Fisher, Ajit P. Limaye

Summary: Mortality among solid organ transplant recipients hospitalized for COVID-19 decreased between early and late 2020, with the late period showing lower mortality even after adjusting for baseline comorbidities. The use of corticosteroids and remdesivir increased, while the use of hydroxychloroquine and IL-6/IL-6 receptor inhibitors decreased between the two periods.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

Article Surgery

The Thoracodorsal Artery Perforator Flap for the Treatment of Hidradenitis Suppurativa of the Axilla: A Prospective Comparative Study

Simone La Padula, Rosita Pensato, Chiara Pizza, Francesco D'Andrea, Giovanni Roccaro, Jean Paul Meningaud, Barbara Hersant

Summary: This study compared the outcomes of different treatment methods for axillary hidradenitis suppurativa (HS) - TDAP flap-based reconstruction versus secondary intention closure, and found that patients who received TDAP flaps had faster recovery, fewer complications, and significant improvements in shoulder function and quality of life.

PLASTIC AND RECONSTRUCTIVE SURGERY (2023)

Review Dermatology

Emerging treatment strategies in wound care

Marjan Mirhaj, Sheyda Labbaf, Mohamadreza Tavakoli, Alexander Marcus Seifalian

Summary: Wound healing is a complex process, and the current treatment strategies face challenges. Dressings and skin substitutes are the most effective, convenient, and cost-effective method for treating chronic wounds, and advances in materials science offer hope for treatment. There is a need to improve current treatment strategies to meet the increasing demands of the aging population and diabetes-related wounds.

INTERNATIONAL WOUND JOURNAL (2022)

Article Surgery

Prevalence of Anosmia and Ageusia in Patients with COVID-19 at a Primary Health Center, Doha, Qatar

Raid M. Al-Ani, Debashis Acharya

Summary: Loss of smell and taste are common complaints in COVID-19 patients, with males, recent travel, smoking, and severe disease course being risk factors for anosmia and ageusia in COVID-19 cases.

INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY (2022)

Article Surgery

Combined Vascular Resection for Locally Advanced Perihilar Cholangiocarcinoma

Takashi Mizuno, Tomoki Ebata, Yukihiro Yokoyama, Tsuyoshi Igami, Junpei Yamaguchi, Shunsuke Onoe, Nobuyuki Watanabe, Yuzuru Kamei, Masato Nagino

Summary: This study evaluated the efficacy and safety of combined vascular resection (VR) in advanced perihilar cholangiocarcinoma (PHC). The results showed that VR surgery salvages a large number of otherwise unresectable advanced PHC patients and provides acceptable surgical outcomes and substantial survival benefits.

ANNALS OF SURGERY (2022)

Article Clinical Neurology

Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer's disease, frontotemporal dementia and progressive supranuclear palsy

Leonidas Chouliaras, Alan Thomas, Maura Malpetti, Paul Donaghy, Joseph Kane, Elijah Mak, George Savulich, Maria A. Prats-Sedano, Amanda J. Heslegrave, Henrik Zetterberg, Li Su, James Benedict Rowe, John Tiernan O'Brien

Summary: This study compared plasma biomarkers for neurodegenerative diseases in different patient groups and found that p-tau181 was elevated in MCI+AD patients with high accuracy in differentiating between different types of dementia. NfL was elevated in all dementia groups, while GFAP was elevated in MCI+AD and LBD.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2022)

Letter Clinical Neurology

mRNA COVID-19 vaccines do not increase the short-term risk of clinical relapses in multiple sclerosis

Massimiliano Di Filippo, Cinzia Cordioli, Simona Malucchi, Pietro Annovazzi, Paola Cavalla, Valentina Torri Clerici, Paolo Ragonese, Viviana Nociti, Marta Radaelli, Alice Laroni, Fabio Buttari, Lorena Lorefice, Diana Ferraro, Alberto Gajofatto, Luca Prosperini, Roberta Fantozzi, Laura Boffa, Roberta Lanzillo, Marcello Moccia, Marinella Clerico, Giovanna De Luca, Valentina Tomassini, Massimiliano Calabrese, Angela Borrelli, Damiano Paolicelli, Giorgia Teresa Maniscalco, Paola Gazzola, Antonio Gallo, Claudio Solaro, Eleonora Cocco, Claudio Gasperini, Carla Tortorella

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2022)

Article Surgery

OPTN/SRTR 2020 Annual Data Report: Lung

M. Valapour, C. J. Lehr, M. A. Skeans, J. M. Smith, E. Miller, R. Goff, T. Mupfudze, K. Gauntt, J. J. Snyder

Summary: In 2020, there was a decrease in the number of lung transplants performed and candidates added to the waiting list, along with a decline in lung donors. This can be attributed to the impact of the global COVID-19 pandemic. However, the median time to transplant continued to decrease and posttransplant survival rates remained stable.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

Article Surgery

The Objective Buttocks Assessment Scale: A New and Complete Method to Assess the Gluteal Region

Giovanni Roccaro, Barbara Hersant, Rosita Pensato, Chiara Pizza, Umberto Rega, Francesco D'Andrea, Jean Paul Meningaud, Simone La Padula

Summary: This study developed a set of grading scales for objective assessment of the gluteal region and found that the scales met criteria for acceptability, reliability, and validity. The study confirmed the reliability of the Objective Buttocks Assessment Scale in female patients and suggested its valuable use in research and clinical practice.

PLASTIC AND RECONSTRUCTIVE SURGERY (2022)

Letter Clinical Neurology

Will COVID-19 change neurosurgical clinical practice?

Nicola Montemurro, Paolo Perrini

BRITISH JOURNAL OF NEUROSURGERY (2022)

Article Surgery

Robotic-assisted Versus Video-assisted Thoracoscopic Lobectomy Short-term Results of a Randomized Clinical Trial (RVlob Trial)

Runsen Jin, Yuyan Zheng, Ye Yuan, Dingpei Han, Yuqin Cao, Yajie Zhang, Chengqiang Li, Jie Xiang, Zhengyuan Zhang, Zhenyi Niu, Toni Lerut, Jules Lin, Abbas E. Abbas, Alessandro Pardolesi, Takashi Suda, Dario Amore, Stefan Schraag, Clemens Aigner, Jian Li, Jiaming Che, Junbiao Hang, Jian Ren, Lianggang Zhu, Hecheng Li

Summary: This study compared the efficacy and perioperative outcomes of robotic-assisted lung cancer surgery (RAL) with video-assisted thoracic surgery (VAL) in patients with non-small cell lung cancer (NSCLC). The study found that both RAL and VAL are safe and feasible for NSCLC treatment, and RAL has an advantage in lymph node yield.

ANNALS OF SURGERY (2022)

Article Cardiac & Cardiovascular Systems

Perioperative outcomes of pulmonary resection after neoadjuvant pembrolizumab in patients with non-small cell lung cancer

Betty C. Tong, Lin Gu, Xiaofei Wang, Dennis A. Wigle, Joseph D. Phillips, David H. Harpole Jr, Jacob A. Klapper, Thomas Sporn, Neal E. Ready, Thomas A. D'Amico

Summary: This study demonstrates that neoadjuvant pembrolizumab is safe and well tolerated in patients with non-small cell lung cancer, and it is not associated with increased surgical morbidity or mortality. Minimally invasive approaches may be more challenging in cases with neoadjuvant immunotherapy. Pathologic response is higher compared to standard neoadjuvant chemotherapy.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2022)

Article Surgery

Actual Five-year Survival After Upfront Resection for Pancreatic Ductal Adenocarcinoma Who Beats the Odds?

Oliver Strobel, Philipp Lorenz, Ulf Hinz, Matthias Gaida, Anna-Katharina Koenig, Thomas Hank, Willem Niesen, Joerg Kaiser, Mohammed Al-Saeedi, Frank Bergmann, Christoph Springfeld, Christoph Berchtold, Markus K. Diener, Martin Schneider, Arianeb Mehrabi, Beat P. Mueller-Stich, Thilo Hackert, Dirk Jaeger, Markus W. Buechler

Summary: This study investigated the actual five-year survival rate of pancreatic ductal adenocarcinoma (PDAC) with a strategy of upfront surgery and adjuvant therapy. The results showed that the actual five-year survival rate for PDAC patients who underwent upfront surgery and adjuvant therapy was 18.8%. Tumor grading, number of positive lymph nodes, intraductal papillary mucinous neoplasia, and vascular resections were found to be independent factors associated with the five-year survival rate.

ANNALS OF SURGERY (2022)

Article Surgery

Kidney transplantation from triple-knockout pigs expressing multiple human proteins in cynomolgus macaques

David Ma, Takayuki Hirose, Grace Lassiter, Hajime Sasaki, Ivy Rosales, Taylor M. Coe, Charles G. Rickert, Rudy Matheson, Robert B. Colvin, Wenning Qin, Yinan Kan, Jacob Layer, Violette B. Paragas, Kathryn Stiede, Katherine C. Hall, Michele E. Youd, Luis M. Queiroz, William F. Westlin, Michael Curtis, Luhan Yang, James F. Markmann, Tatsuo Kawai

Summary: The study demonstrates that long-term survival of renal xenografts from TKO pigs can be achieved in cynomolgus monkeys through the expression of additional human transgenes. The level of CRP expression was found to be associated with recipient survival time.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

Article Surgery

The Face- and Neck-Lift Objective Photo-Numerical Assessment Scale: A Complete Scale for Face-Lift Evaluation

Simone La Padula, Edoardo Coiante, Chiara Pizza, Francesco D'Andrea, Umberto Rega, Barbara Hersant, Jean Paul Meningaud

Summary: The study aimed to develop and validate a new tool, the Face- and Neck-Lift Objective Photo-Numerical Assessment Scale, for objectively assessing outcomes of face and neck-lift procedures. The scale was found to be acceptable, reliable, and valid, with good interrater and intrarater reliabilities. This scale can serve as an important metric for clinical research in facial rejuvenation surgery.

PLASTIC AND RECONSTRUCTIVE SURGERY (2023)

Review Orthopedics

Robotic-arm assisted total knee arthroplasty is associated with improved accuracy and patient reported outcomes: a systematic review and meta-analysis

Junren Zhang, Wofhatwa Solomon Ndou, Nathan Ng, Paul Gaston, Philip M. Simpson, Gavin J. Macpherson, James T. Patton, Nicholas D. Clement

Summary: This study compared the accuracy of component positioning, patient-reported outcomes, and complications of robotic-arm assisted total knee arthroplasty with manual TKA and analyzed the associated learning curve. The results showed that RATKA performed better in terms of component positioning accuracy and patient-reported outcomes.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY (2022)

Article Surgery

Association between Acute Pancreatitis and COVID-19: Could Pancreatitis Be the Missing Piece of the Puzzle about Increased Mortality Rates?

Cevher Akarsu, Mehmet Karabulut, Husnu Aydin, Nuri Alper Sahbaz, Ahmet Cem Dural, Duygu Yegul, Kivanc Derya Peker, Sina Ferahman, Sezer Bulut, Turgut Donmez, Sinan Asar, Kadriye Kart Yasar, Gokhan Tolga Adas

Summary: This study evaluated the incidence and clinical manifestations of acute pancreatitis in COVID-19 patients. The results showed that COVID-19 patients with acute pancreatitis had higher hospitalization and mortality rates, and were associated with age, C-reactive protein, and ferritin levels.

JOURNAL OF INVESTIGATIVE SURGERY (2022)

Article Otorhinolaryngology

Radiofrequency ablation and related ultrasound-guided ablation technologies for treatment of benign and malignant thyroid disease: An international multidisciplinary consensus statement of the American Head and Neck Society Endocrine Surgery Section with the Asia Pacific Society of Thyroid Surgery, Associazione Medici Endocrinologi, British Association of Endocrine and Thyroid Surgeons, European Thyroid Association, Italian Society of Endocrine Surgery Units, Korean Society of Thyroid Radiology, Latin American Thyroid Society, and Thyroid Nodules Therapies Association

Lisa A. Orloff, Julia E. Noel, Brendan C. Stack, Marika D. Russell, Peter Angelos, Jung Hwan Baek, Kevin T. Brumund, Feng-Yu Chiang, Mary Beth Cunnane, Louise Davies, Andrea Frasoldati, Anne Y. Feng, Laszlo Hegedus, Ayaka J. Iwata, Emad Kandil, Jennifer Kuo, Celestino Lombardi, Mark Lupo, Ana Luiza Maia, Bryan McIver, Dong Gyu Na, Roberto Novizio, Enrico Papini, Kepal N. Patel, Leonardo Rangel, Jonathon O. Russell, Jennifer Shin, Maisie Shindo, David C. Shonka, Amanda S. Karcioglu, Catherine Sinclair, Michael Singer, Stefano Spiezia, Jose Higino Steck, David Steward, Kyung Tae, Neil Tolley, Roberto Valcavi, Ralph P. Tufano, R. Michael Tuttle, Erivelto Volpi, Che Wei Wu, Amr H. Abdelhamid Ahmed, Gregory W. Randolph

Summary: This document provides a comprehensive review of the current status of ultrasound-guided ablation procedures for benign and malignant thyroid conditions, along with 18 best practice recommendations in various topic areas. As ultrasound-guided ablation procedures become more common in thyroid disease treatment, evidence-based and thoughtful implementation of best practices is essential.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2022)

Article Orthopedics

Higher satisfaction after total knee arthroplasty using restricted inverse kinematic alignment compared to adjusted mechanical alignment

Philip Winnock de Grave, Thomas Luyckx, Kurt Claeys, Thomas Tampere, Jonas Kellens, Jacobus Mueller, Paul Gunst

Summary: The purpose of this study was to compare the clinical outcomes of restricted inverse kinematic alignment (iKA) and adjusted mechanical alignment (aMA) techniques in robotic-assisted total knee arthroplasty (TKA). The results showed similar clinical outcomes between the two techniques at a 12-month follow-up, but the restricted iKA technique had better satisfaction and achieved higher OKS and satisfaction thresholds.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY (2022)