Surgery 类别的文章 - Peeref

Article Surgery

Neutralization against Omicron variant in transplant recipients after three doses of mRNA vaccine

Deepali Kumar, Queenie Hu, Reuben Samson, Victor H. Ferreira, Victoria G. Hall, Matthew Ierullo, Beata Majchrzak-Kita, William Hardy, Anne-Claude Gingras, Atul Humar

Summary: The Omicron variant of the SARS-CoV-2 virus has become the dominant circulating strain globally, and three doses of mRNA COVID-19 vaccine are recommended for transplant recipients. However, there is limited research on the immunogenicity of mRNA vaccines specifically against the Omicron variant. This study analyzed the neutralization effects of Omicron in transplant recipients who received three doses of mRNA-1273 vaccine, and the results showed poor neutralizing responses against the Omicron variant in these patients.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

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Review Surgery

Surgical Management of Gastric Cancer A Review

George Z. Li, Gerard M. Doherty, Jiping Wang

Summary: Surgery is crucial in the management of gastric cancer at all stages. Early gastric cancer patients with low risk of lymph node metastasis can potentially be cured with endoscopic therapy or surgery alone. Patients with later-stage localized gastric cancer benefit from extensive lymphadenectomy and multimodality therapy. Ongoing studies are investigating novel surgical approaches and peritoneal-directed therapies.

JAMA SURGERY (2022)

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Article Surgery

Survival After Hyperthermic Intraperitoneal Chemotherapy and Primary or Interval Cytoreductive Surgery in Ovarian Cancer A Randomized Clinical Trial

Myong Cheol Lim, Suk-Joon Chang, Boram Park, Heon Jong Yoo, Chong Woo Yoo, Byung Ho Nam, Sang-Yoon Park

Summary: The study aimed to evaluate the clinical benefit of HIPEC in patients with ovarian cancer. The results showed that adding HIPEC to cytoreductive surgery did not improve survival rates for patients with advanced ovarian cancer. However, in the subgroup of interval cytoreductive surgery, the addition of HIPEC improved progression-free and overall survival.

JAMA SURGERY (2022)

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Article Surgery

The Most Current Algorithms for the Treatment and Prevention of Hypertrophic Scars and Keloids: A 2020 Update of the Algorithms Published 10 Years Ago

Rei Ogawa

Summary: This article reviewed and updated the literature on hypertrophic scars and keloids. The findings suggest that treatment methods depend on the severity and number of scars, while prevention methods include local factors, systemic factors, genetic factors, and lifestyle factors. Conservative therapy is the preferred treatment for keloids, but surgery is necessary for severe scars.

PLASTIC AND RECONSTRUCTIVE SURGERY (2022)

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Article Surgery

Early clinical experience with nirmatrelvir/ritonavir for the treatment of COVID-19 in solid organ transplant recipients

David M. Salerno, Douglas L. Jennings, Nicholas W. Lange, Danielle (Bley) Kovac, Tara Shertel, Justin K. Chen, Jessica Hedvat, Jenna Scheffert, Robert S. Brown, Marcus R. Pereira

Summary: The use of Nirmatrelvir/ritonavir (NR) in solid organ transplant recipients (SOTRs) with mild COVID-19 has not been described yet. The objective of this study was to evaluate outcomes among SOTRs and describe the drug-drug interaction of NR. The results show that the clinically significant interaction between NR and immunosuppressive agents can be reasonably managed with a standardized dosing protocol.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

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Article Surgery

Oncological Outcomes After Anastomotic Leakage After Surgery for Colon or Rectal Cancer Increased Risk of Local Recurrence

Thomas W. A. Koedam, Boukje T. Bootsma, Charlotte L. Deijen, Tim van de Brug, Geert Kazemier, Miguel A. Cuesta, Alois Furst, Antonio M. Lacy, Eva Haglind, Jurriaan B. Tuynman, Freek Daams, Hendrik J. Bonjer

Summary: Anastomotic leakage after rectal cancer surgery negatively affects long-term oncological outcomes, leading to increased local recurrences and decreased disease-free survival. However, its impact on outcomes after colon cancer surgery remains inconclusive.

ANNALS OF SURGERY (2022)

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Article Cell Biology

Chronic wounds: Treatment consensus

Elof Eriksson, Paul Y. Liu, Gregory S. Schultz, Manuela M. Martins-Green, Rica Tanaka, Dot Weir, Lisa J. Gould, David G. Armstrong, Gary W. Gibbons, Randy Wolcott, Oluyinka O. Olutoye, Robert S. Kirsner, Geoffrey C. Gurtner

Summary: The Wound Healing Foundation (WHF) organized a virtual meeting to establish a consensus on the best treatment for chronic wounds. The meeting covered topics such as diagnosis, debridement, infection control, dressings, grafting, pain management, oxygen treatment, outcomes, and future needs. Key takeaways included the need for simplified wound care, the potential benefits of telemonitoring, and the importance of defining patient expectations.

WOUND REPAIR AND REGENERATION (2022)

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Article Surgery

Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss, Comorbidities, and Reflux at 10 Years in Adult Patients With Obesity The SLEEVEPASS Randomized Clinical Trial

Paulina Salminen, Sofia Gronroos, Mika Helmio, Saija Hurme, Anne Juuti, Risto Juusela, Pipsa Peromaa-Haavisto, Marja Leivonen, Pirjo Nuutila, Jari Ovaska

Summary: This study compared the long-term outcomes of laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) at 10 years. The results showed that LRYGB resulted in greater weight loss compared to LSG. However, both procedures were effective in achieving sustainable weight loss. LSG was associated with a higher prevalence of gastroesophageal reflux symptoms, while the occurrence of Barrett esophagus was similar between the two procedures.

JAMA SURGERY (2022)

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Article Neuroimaging

European Stroke Organisation (ESO)-European Society for Minimally Invasive Neurological Therapy (ESMINT) expedited recommendation on indication for intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and anterior circulation large vessel occlusion

Guillaume Turc, Georgios Tsivgoulis, Heinrich J. Audebert, Hieronymus Boogaarts, Pervinder Bhogal, Gian Marco De Marchis, Ana Catarina Fonseca, Pooja Khatri, Mikael Mazighi, Natalia Perez de la Ossa, Peter D. Schellinger, Daniel Strbian, Danilo Toni, Philip White, William Whiteley, Andrea Zini, Wim van Zwam, Jens Fiehler

Summary: This study evaluated whether mechanical thrombectomy (MT) alone is non-inferior to intravenous thrombolysis (IVT) plus MT in patients with anterior circulation large vessel occlusion (LVO) ischemic stroke. The recommendations suggest using IVT plus MT for patients directly admitted to a MT-capable center within 4.5 hours of symptoms onset, and IVT followed by rapid transfer to a MT-capable center for patients admitted to a center without MT facilities.

JOURNAL OF NEUROINTERVENTIONAL SURGERY (2022)

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Article Surgery

TransCarotid Revascularization With Dynamic Flow Reversal Versus Carotid Endarterectomy in the Vascular Quality Initiative Surveillance Project

Mahmoud B. Malas, Hanaa Dakour-Aridi, Vikram S. Kashyap, Jens Eldrup-Jorgensen, Grace J. Wang, Raghu L. Motaganahalli, Jack L. Cronenwett, Marc L. Schermerhorn

Summary: This study compared the outcomes of TCAR with flow reversal to the gold standard CEA and found that TCAR significantly reduces the risk of postoperative myocardial infarction and cranial nerve injury compared to CEA, with no differences in the rates of stroke/death.

ANNALS OF SURGERY (2022)

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Article Surgery

Leveraging diverse cell-death patterns to predict the prognosis and drug sensitivity of triple-negative breast cancer patients after surgery

Yutian Zou, Jindong Xie, Shaoquan Zheng, Wenqing Liu, Yuhui Tang, Wenwen Tian, Xinpei Deng, Linyu Wu, Yue Zhang, Duxun Tan, Qing Liu, Xiaoming Xie

Summary: A cell death index (CDI) model was established to accurately predict the clinical prognosis and drug sensitivity of triple-negative breast cancer (TNBC) after surgery. Patients with high CDI had a worse prognosis and were associated with immune checkpoint genes and tumor microenvironment components.

INTERNATIONAL JOURNAL OF SURGERY (2022)

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Article Dermatology

Our contemporary understanding of the aetiology of pressure ulcers/pressure injuries

Amit Gefen, David M. Brienza, Janet Cuddigan, Emily Haesler, Jan Kottner

Summary: The third edition of the Clinical Practice Guideline on Prevention and Treatment of Pressure Ulcers/Injuries, published in 2019, provides clinicians with updated evidence-based guidance on pressure ulcers. The guideline also discusses the etiology, classification, and future research needs related to pressure ulcers. Research shows that sustained soft tissue deformations can lead to cell death, tissue damage, and the formation of pressure ulcers/pressure injuries. In order to prevent pressure ulcers, it is important to minimize deformations in tissues by reducing peak strain/stress values or decreasing exposure time.

INTERNATIONAL WOUND JOURNAL (2022)

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Article Surgery

Robot-assisted Versus Conventional Minimally Invasive Esophagectomy for Resectable Esophageal Squamous Cell Carcinoma Early Results of a Multicenter Randomized Controlled Trial: the RAMIE Trial

Yang Yang, Bin Li, Jun Yi, Rong Hua, Hezhong Chen, Lijie Tan, Hecheng Li, Yi He, Xufeng Guo, Yifeng Sun, Bentong Yu, Zhigang Li

Summary: This study compared the outcomes of robot-assisted minimally invasive esophagectomy (RAMIE) and conventional minimally invasive esophagectomy (MIE) in the treatment of esophageal squamous cell carcinoma (ESCC). The results showed that RAMIE had shorter operation time and better lymph node dissection in patients who received neoadjuvant therapy. RAMIE and MIE had similar rates of complications and postoperative complications.

ANNALS OF SURGERY (2022)

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Article Orthopedics

AAOS Clinical Practice Guideline Summary: Management of Osteoarthritis of the Knee (Nonarthroplasty), Third Edition

Robert H. Brophy, Yale A. Fillingham

Summary: This article presents an evidence-based clinical practice guideline for the management of knee osteoarthritis without joint replacement surgery. The guideline includes both nonpharmacologic and pharmacologic interventions for symptomatic knee osteoarthritis. It provides 29 recommendations for healthcare professionals and information for patients. The article also emphasizes the need for further research on intra-articular corticosteroids, hyaluronic acid, and platelet-rich plasma.

JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS (2022)

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Review Gastroenterology & Hepatology

Therapeutic endoscopic ultrasound: European Society of Gastrointestinal Endoscopy (ESGE) Technical Review

Roy L. J. van Wanrooij, Michiel Bronswijk, Rastislav Kunda, Simon M. Everett, Sundeep Lakhtakia, Mihai Rimbas, Tomas Hucl, Abdenor Badaoui, Ryan Law, Paolo Giorgio Arcidiacono, Alberto Larghi, Marc Giovannini, Mouen A. Khashab, Kenneth F. Binmoeller, Marc Barthet, Manuel Perez-Miranda, Jeanin E. van Hooft, Schalk W. van der Merwe

Summary: This article summarizes the recommendations of ESGE on therapeutic endoscopic ultrasound (EUS) procedures, including the use of prophylactic antibiotics, self-expandable metal stents for biliary drainage, limitations on pancreatic duct drainage, stepwise approach for pancreatic duct drainage, transduodenal gallbladder drainage with LAMS, small-bowel distension with saline instillation, saline instillation and LAMS for EUS-directed transgastric endoscopic retrograde cholangiopancreatography (EDGE) procedures, and preference for 20-mm LAMSs for EDGE.

ENDOSCOPY (2022)

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Letter Surgery

Nirmatrelvir/ritonavir use: Managing clinically significant drug-drug interactions with transplant immunosuppressants

Nicholas W. Lange, David M. Salerno, Douglas L. Jennings, Jason Choe, Jessica Hedvat, Danielle (Bley) Kovac, Jenna Scheffert, Tara Shertel, Lloyd E. Ratner, Robert S. Brown, Marcus R. Pereira

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

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Letter Surgery

The recently emerged BA.4 and BA.5 lineages of Omicron and their global health concerns amid the ongoing wave of COVID-19 pandemic - Correspondence

Ranjan K. Mohapatra, Venkataramana Kandi, Ashish K. Sarangi, Sarika Verma, Hardeep Singh Tuli, Sandip Chakraborty, Chiranjib Chakraborty, Kuldeep Dhama

INTERNATIONAL JOURNAL OF SURGERY (2022)

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Article Surgery

Outcomes of a Multicenter Training Program in Robotic Pancreatoduodenectomy (LAELAPS-3)

Maurice J. W. Zwart, Carolijn L. M. Nota, Thijs de Rooij, Jony van Hilst, Wouter W. te Riele, Hjalmar C. C. van Santvoort, Jeroen Hagendoorn, Inne H. M. Borei Rinkes, Jacob L. L. van Dam, Anouk E. J. Latenstein, Kosei Takagi, Khe T. C. Tran, Jennifer Schreinemakers, George P. P. van der Schelling, Jan H. H. Wijsman, Sebastiaan Festen, Freek Daams, Misha D. D. Luyer, Ignace H. J. T. de Hingh, Jan S. D. Mieog, Bert A. A. Bonsing, Daan J. J. Lips, Mohammed Abu Hilal, Olivier R. R. Busch, Olivier Saint-Marc, Herbert J. J. Zehl II, Amer H. H. Zureikat, Melissa E. E. Hogg, I. Quintus Molenaar, Marc G. G. Besselink, Bas Groot Koerkamp, Dutch Pancreatic Canc Grp

Summary: This study assessed the feasibility and safety of a multicenter training program in robotic pancreatoduodenectomy (RPD) and found that it was feasible without a negative impact from the learning curve on clinical outcomes.

ANNALS OF SURGERY (2022)

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Article Clinical Neurology

2021 Japanese Guidelines for the Management of Moyamoya Disease: Guidelines from the Research Committee on Moyamoya Disease and Japan Stroke Society

Miki Fujimura, Teiji Tominaga, Satoshi Kuroda, Jun C. Takahashi, Hidenori Endo, Kuniaki Ogasawara, Susumu Miyamoto

NEUROLOGIA MEDICO-CHIRURGICA (2022)

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Article Surgery

OPTN/SRTR 2020 Annual Data Report: Kidney

K. L. Lentine, J. M. Smith, A. Hart, J. Miller, M. A. Skeans, L. Larkin, A. Robinson, K. Gauntt, A. K. Israni, R. Hirose, J. J. Snyder

Summary: The year 2020 presented challenges for kidney transplantation, with a slight decrease in the total number of transplants and a significant decline in living donor transplants due to the COVID-19 pandemic. Racial disparities in living donor transplant access persist. Pediatric kidney transplants were also impacted, with a decrease in the total number of transplants and a continued decrease in deceased donor transplants among pediatric candidates.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

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