Respiratory System

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Article Cardiac & Cardiovascular Systems

Serum proteomic analysis in esophagectomy patients with postoperative delirium: A case-control study

Sikandar H. Khan, Anthony J. Perkins, Samreen Jawaid, Sophia Wang, Heidi Lindroth, Rebecca E. Schmitt, Jason Doles, Jason D. True, Sujuan Gao, Gideon A. Caplan, Homer L. Twigg III, Kenneth Kesler, Babar A. Khan

Summary: This study aimed to identify protein pathways associated with delirium post-esophagectomy. The findings revealed that coagulation factor IX and mannosyl-oligosaccharide 1,2-alpha-mannosidase were associated with delirium, while complement C2 and mannosyl-oligosaccharide 1,2-alpha-mannosidase were associated with delirium severity.

HEART & LUNG (2024)

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Review Cardiac & Cardiovascular Systems

Efficacy and safety of fluticasone propionate/salmeterol and fluticasone propionate monotherapy in step-up treatment of childhood asthma: A systematic review and meta-analysis

Hua Li, Tao Dong, Jinling Luan

Summary: Fluticasone propionate and salmeterol (FSC) are viable options for step-up treatment in asthmatic children, as they can reduce the incidence of asthma exacerbations and improve lung function. FSC treatment for more than 12 weeks shows a greater likelihood of reducing asthma exacerbations and decreasing the use of albuterol. There were no significant differences in drug-related adverse events between FSC and fluticasone propionate (FP) alone.

HEART & LUNG (2024)

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Article Respiratory System

Transbronchial cryobiopsy for small peripheral pulmonary lesions using endobronchial ultrasonography and an ultrathin bronchoscope

Toshiyuki Sumi, Yuichi Yamada, Yuta Koshino, Hiroki Watanabe, Daiki Nagayama, Haruhiko Michimata, Keito Suzuki, Takumi Ikeda, Kotomi Terai, Koichi Osuda, Yusuke Tanaka, Hirofumi Chiba

Summary: Combining transbronchial cryobiopsy (TBCB) with forceps biopsy using a 1.1-mm cryoprobe during ultrathin bronchoscopy improves the diagnostic yield for lesions adjacent to the rEBUS probe.

RESPIRATORY INVESTIGATION (2024)

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Article Cardiac & Cardiovascular Systems

High level of psychosocial adjustment in patients on ongoing ventricular assist device support in the years one to three after VAD implantation-A national multi-center Study

Hannah Spielmann, Wolfgang Albert, Sandra Semmig-Koenze, Volker Lauenroth, Christine Spitz-Koeberich, Paulina Staus, Katharina Tigges-Limmer, Christiane Kugler, S. E. L. M. A. Study SELMA Study Grp

Summary: This study investigated the construct of psychosocial adjustment and the role of social support in patients with durable VAD support. The results showed that the majority of the participants reported high levels of perceived social support and good psychosocial adjustment. Higher levels of perceived social support were associated with lower levels of anxiety and depression, and higher levels of quality of life.

HEART & LUNG (2024)

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Article Oncology

A case of a shrunken multilocular mediastinal cyst that developed into thymic carcinoma with lung metastases 13 years later

Kazuto Sugai, Kojiro Nakaoka, Rika Tobita, Shinji Kikuchi, Kei Inoue, Midori Enokido, Moriyuki Kiyoshima

Summary: This article presents a case of multilocular mediastinal cyst leading to the development of thymic cancer. Resection of multilocular anterior mediastinal cysts should be considered due to the challenges in preoperative diagnosis, the potential for coexisting tumors with cysts, and the risk of malignant tumor development.

THORACIC CANCER (2024)

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Article Cardiac & Cardiovascular Systems

Urban Zen integrative therapy: Understanding intervention delivery adherence

Tania T. Von Visger, Ji Won Shin, Mary Beth Happ

Summary: This study explores the perspectives of Urban Zen Integrative Therapy interventionists on the delivery of the therapy, aiming to gain a deeper understanding of subjective variables that may influence intervention fidelity. The results reveal several key themes related to adherence to the intervention delivery, such as balancing between tailoring and standardization, challenges faced during delivery, the need for teamwork, and clients' application of the therapy.

HEART & LUNG (2024)

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Review Oncology

Advances in new targets for immunotherapy of small cell lung cancer

Zitong Zheng, Juanjuan Liu, Junling Ma, Runting Kang, Zhen Liu, Jiangyong Yu

Summary: Small cell lung cancer (SCLC) is a highly aggressive malignancy with limited treatment options. Over the past decade, immunotherapy has made progress in the treatment of SCLC, but current immune checkpoint inhibitors have limited benefits for patient survival. Therefore, it is important to explore new targets and develop drugs with novel mechanisms for immunotherapy in SCLC.

THORACIC CANCER (2024)

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Article Cardiac & Cardiovascular Systems

Cardiac rehabilitation phase II outcomes prior and during COVID

Harrison Krebs, Kimberly Crutcher, Yan Su, Marilyn A. Prasun

Summary: During the COVID pandemic, patients experienced increased depression and poorer quality of life. However, significant improvements were observed in all outcomes following completion of Cardiac Rehabilitation (CR).

HEART & LUNG (2024)

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Review Cardiac & Cardiovascular Systems

Sedation and analgesia strategies for non-invasive mechanical ventilation: A systematic review and meta-analysis

Baolu Yang, Leyi Gao, Zhaohui Tong

Summary: The use of sedative and analgesic medications during non-invasive ventilation can reduce the risk of tracheal intubation and delirium in patients with acute respiratory failure. Among the different medications, dexmedetomidine showed better clinical outcomes, especially when closely monitoring the patients' vital signs.

HEART & LUNG (2024)

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Article Cardiac & Cardiovascular Systems

Which Components of The International Classification of Functioning, Disability and Health (ICF) are Covered by Cardiac Rehabilitation Assessment Tools among Individuals with Heart Failure?

Eriadina Alves Lima, Gezabell Rodrigues, Beatriz Carneiro Mota, Shamyr Sulyvan Castro, Rafael Barreto Mesquita, Camila Ferreira Leite

Summary: This study investigated the components of the International Classification of Functioning, Disability and Health (ICF) reflected in the assessment instruments used in cardiac rehabilitation for individuals with heart failure (HF). The results showed that body function was the most frequently detected component, but none of the instruments covered all aspects of the ICF. The Minnesota Living with Heart Failure Questionnaire (MLHFQ) demonstrated the most comprehensive coverage of ICF components.

HEART & LUNG (2024)

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Article Physiology

Effects of body postures on respiratory muscle force and coughing in healthy people

Rui Yu, Tatsuma Okazaki, Yuzhuo Ren, Junko Okuyama, Satoru Ebihara, Shin-Ichi Izumi

Summary: Body postures significantly influence respiratory muscle force, cough pressure, subjective ease of coughing, and pulmonary function. The 60-degree semi-recumbent posture and sitting posture show better results compared to the supine posture.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2024)

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Review Cardiac & Cardiovascular Systems

Effects of ventilatory bundles on patient outcomes among ICU patients: A systematic review and meta-analysis

Dejina Thapa, Sek Ying Chair, Mei Sin Chong, Rishi Ram Poudel, Tenaw Gualau Melesse, Kai Chow Choi, Hon Lon Tam

Summary: The ventilator bundle has been found to effectively reduce the incidence of ventilator-associated pneumonia and improve related outcomes. However, caution should be exercised in interpreting these findings due to the low-to-moderate certainty of evidence and high heterogeneity.

HEART & LUNG (2024)

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Article Physiology

Physiological responses during static apnoea efforts in elite and novice breath-hold divers before and after two weeks of dry apnoea training

Dimitrios I. Bourdas, Nickos D. Geladas

Summary: This study examined the effects of breath-hold training on the performance of novice and elite breath-hold divers. The results showed that breath-hold training significantly improved red blood cell concentration, hemoglobin oxygen saturation steady state duration, and breath-hold time in novice divers. Elite divers had better breath-hold performance and higher peak mean arterial pressure compared to novices. The study suggests that breath-hold training can enhance the performance of divers.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2024)

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Article Physiology

Insights into exercise-induced rhinitis based on nasal aerodynamics induced by airway morphology

Sarah M. Russel, Raluca E. Gosman, Katherine Gonzalez, Joshua Wright, Dennis O. Frank-Ito

Summary: This study aimed to characterize the response of different nasal morphologies to airflow-related variables during rapid/deep inspiration. The results showed that notched nasal vestibules had higher resistance values and airflow velocities, while standard nasal vestibules had higher mucosal heat flux. Different nasal phenotypes may predispose individuals to exercise-induced rhinitis.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2024)

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Article Physiology

Cough and swallow after laparotomy in anesthetized cats

Ivan Poliacek, Lukas Martvon, Michal Simera, Marcel Veternik, Jakub Misek, Lucia Cibulkova, Kimberly E. Iceman, Donald C. Bolser, Teresa Pitts

Summary: An animal model study evaluated the effects of an abdominal incision on cough and swallow, revealing that abdominal wall manipulations can increase pharyngeal muscle activity during swallow without affecting the cough reflex. Swallowing tended to occur more during the inspiratory phase. The results highlight the important role of abdominal wall sensory feedback in regulating swallow motor patterns.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2024)

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Article Respiratory System

Concordance between transbronchial lung cryobiopsy and surgical lung biopsy in patients with idiopathic multicentric Castleman disease: A report of four cases

Ryota Otoshi, Hideya Kitamura, Tomohisa Baba, Tatsuya Muraoka, Akimasa Sekine, Tamiko Takemura, Koji Okudela, Tomoe Sawazumi, Takashi Ogura

Summary: This study retrospectively reviewed the efficacy of transbronchial lung cryobiopsy (TBLC) in the diagnosis of idiopathic multicentric Castleman disease (iMCD). The results showed that TBLC was able to evaluate the extent of lung lesions, inflammatory cell infiltration, and the presence of lymphoid follicles in iMCD patients.

RESPIRATORY INVESTIGATION (2024)

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Letter Physiology

Pulmonary oxygen toxicity index during linear change in PO2: HBO treatment tables and dive planning

R. Arieli

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2024)

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Article Oncology

Different effects of crizotinib treatment in two non-small cell lung cancer patients with SDC4::ROS1 fusion variants

Yuta Ohishi, Yoko Nakanishi, Yukari Hirotani, Atsuko Suzuki, Tomoyuki Tanino, Haruna Nishimaki-Watanabe, Hiroko Kobayashi, Fumi Nozaki, Sumie Ohni, Xiaoyan Tang, Kentaro Hayashi, Yoshiko Nakagawa, Tetsuo Shimizu, Ichiro Tsujino, Noriaki Takahashi, Yasuhiro Gon, Shinobu Masuda

Summary: This study aimed to investigate the clinicopathological differences and therapeutic response of NSCLC patients with SDC4::ROS1 fusion to crizotinib. The study found that different ROS1 fusion partners may affect the efficacy of crizotinib and patient prognosis. In addition, higher expression levels of ROS1 and pERK1/2 in tumor cells of case 2 may be related to the therapeutic response and prognosis.

THORACIC CANCER (2024)

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Article Cardiac & Cardiovascular Systems

The psychometric properties of the Chinese version of the Interoceptive Awareness Questionnaire (IAQ) among cardiovascular disease

Liu Huang, Mengtao Song, Ling Wang, Qiran Zhang, Xiao Liu, Chunfeng Cai

Summary: This study examines the reliability and validity of the Chinese Interoceptive Awareness Questionnaire (C-IAQ) for Chinese cardiovascular disease (CVD) patients. The results indicate that the C-IAQ has favorable psychometric features and can be used to measure the interoceptive awareness of CVD patients.

HEART & LUNG (2024)

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Article Respiratory System

Outcomes of patients with elevated pulmonary artery systolic pressure on echocardiography due to chronic lung diseases

Moiz Salahuddin, Shayan Shahid, Umar Tariq, Masooma Aqeel, Ali Usman Arif, Mehwish Aslam, Saadia Sattar

Summary: Pulmonary hypertension is associated with increased mortality, and echocardiographic findings of elevated PASP may be a prognostic factor for 1-year mortality in patients with chronic lung diseases. Patients with elevated PASP, 1-year hospital readmission, and underlying interstitial lung disease or bronchiectasis have increased odds of 1-year mortality.

RESPIRATORY INVESTIGATION (2024)

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