Article
Oncology
Maria Thor, Kelly Fitzgerald, Aditya Apte, Jung Hun Oh, Aditi Iyer, Otasowie Odiase, Saad Nadeem, Ellen D. Yorke, Jamie Chaft, Abraham J. Wu, Michael Offin, Charles B. Simone Ii, Isabel Preeshagul, Daphna Y. Gelblum, Daniel Gomez, Joseph O. Deasy, Andreas Rimner
Summary: The purpose of this study was to identify predictors of disease progression in early-stage non-small cell lung cancer (NSCLC) patients after receiving definitive stereotactic body radiation therapy (SBRT). The results showed that tumor diameter and SUVmax were the most frequently reported features associated with progression/survival, and a re-fitted model including these two features had the best performance.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Michael Waters, Alex Price, Eric Laugeman, Lauren Henke, Geoff Hugo, Hayley Stowe, Neal Andruska, Randall Brenneman, Yao Hao, Olga Green, Clifford Robinson, Hiram Gay, Jeff Michalski, Brian C. Baumann
Summary: The study evaluated the clinical utility of an AI-augmented CT-based adaptive SBRT system for prostate cancer treatment. Results showed that adaptive treatment plans significantly improved target coverage and reduced dose to critical organs.
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY
(2024)
Article
Oncology
Victor Zamora, Olatz Garin, Jose Francisco Suarez, Cristina Gutierrez, Ferran Guedea, Patricia Cabrera, Manuel Castells, Ismael Herruzo, Lluis Fumado, Pilar Samper, Carlos Ferrer, Lucas Regis, Angels Pont, Montse Ferrer
Summary: There is a lack of comparative effectiveness research on new treatment modalities for localized prostate cancer. This study aimed to compare the impact of active surveillance, robot-assisted radical prostatectomy (RARP), intensity-modulated radiotherapy (IMRT), and real-time brachytherapy using Patient-Reported Outcome Measures (PROMs). The results showed that active surveillance had the fewest side effects, but led to significant deterioration in sexual and physical health, while showing moderate improvement in mental health. RARP had greater urinary incontinence, and IMRT and real-time brachytherapy were associated with worse bowel symptoms. Most side effects seemed to be limited to short-term deteriorations.
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY
(2024)
Article
Computer Science, Artificial Intelligence
Yan Wang, Yanmei Luo, Chen Zu, Bo Zhan, Zhengyang Jiao, Xi Wu, Jiliu Zhou, Dinggang Shen, Luping Zhou
Summary: This paper proposes a method for high-quality SPET reconstruction using low-dose PET images and T1 acquisitions from MRI. It extracts local spatial features from different modalities using separate CNN encoders and integrates these features effectively using a multimodal feature integration module. It further uses a Transformer-based encoder to extract global semantic information and a CNN decoder to transform the encoded features into SPET images. Additionally, a patch-based discriminator and an edge-aware loss are applied to retain edge detail information in the reconstructed SPET images. Experimental results demonstrate that the proposed method outperforms current state-of-the-art methods in reconstructing high-quality SPET images.
MEDICAL IMAGE ANALYSIS
(2024)
Article
Computer Science, Artificial Intelligence
Jian Dai, Tiange Liu, Drew A. Torigian, Yubing Tong, Shiwei Han, Pengju Nie, Jing Zhang, Ran Li, Fei Xie, Jayaram K. Udupa
Summary: In this study, a method for segmenting body composition tissues is proposed, which can automatically delineate key tissues and facilitate the diagnosis and treatment of various diseases, making it of great significance.
MEDICAL IMAGE ANALYSIS
(2024)
Review
Oncology
Matthew Fok, Rhianna Hill, Hayley Fowler, Rachael Clifford, Aaron Kler, Jayanma Uzzi-Daniel, Sonia Rocha, Gabrielle Grundy, Jason Parsons, Dale Vimalachandran
Summary: This systematic review evaluates the potential effectiveness of targeting hypoxia-induced radioresistance in rectal cancer and highlights the importance of further research in this area. There is a need for more preclinical and clinical studies to fully understand the mechanism behind this radioresistance. Promising targets have been identified, but more research is needed.
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jae Sung Lee, Min Sun Lee
Article
Radiology, Nuclear Medicine & Medical Imaging
Paolo Castellucci, Riccardo Mei, Andrea Farolfi, Cristina Nanni, Stefano Fanti
Summary: A dedicated PET tomograph has great clinical utility in examining the prostate gland, particularly in assessing high-risk patients before biopsy. It can reduce the need for biopsy samples, define tumor location, assist in focal therapies, and improve N staging accuracy in this potentially fatal malignancy.
Letter
Acoustics
Bernard Cosyns, Sharon L. Mulvagh
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Shyamala Guruvare, Shripad Hebbar, Lakshmi Bai, Padmapriya Jaiprakash, Deepa Reddy, Deepa Hc
Summary: This study assessed the accuracy of 3-D surface rendering of 2-D ultrasound images of the uterus using FMRA software for mapping uterine fibroids compared to pathological evaluation. The results showed good correlation between the two methods in terms of fibroid size and location. Inter-observer analysis also demonstrated reproducibility of measurements from two sonologists using the 3-D model.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marlon Bran Lorenzana, Shekhar S. Chandra, Feng Liu
Summary: Sparse reconstruction is important in MRI for reducing acquisition time and improving spatial-temporal resolution. This paper introduces two decoupling techniques for explicit 1D regularization and a combined 1D + 2D reconstruction technique that improves image quality.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Oncology
Stephanie Gulstene, Pencilla Lang, Melody Qu, Joanna M. Laba, Brian P. Yaremko, George B. Rodrigues, Edward Yu, Mehdi Qiabi, Rahul Nayak, Richard A. Malthaner, Dalilah Fortin, Andrew Warner, Richard I. Inculet, David A. Palma
Summary: Purpose: This study evaluates the frequency of progressive disease (PD) as determined by the Response Evaluation Criteria in Solid Tumors (RECIST) following lung stereotactic ablative radiotherapy (SABR), and correlates this with actual treatment outcomes. The results show that most lesions identified as PD by RECIST criteria do not represent recurrence, highlighting the limitations of RECIST in this setting.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Chemistry, Inorganic & Nuclear
P. G. Konstantinidis, G. S. Polymeris, E. Tsoutsoumanos, G. Kitis
Summary: This study investigates an altered version of an existing protocol to study the mechanisms and phenomena of stimulated luminescence. The protocol allows for the examination of recombination mechanisms and trapping parameters of the traps, as well as the observation of potential transitions between two different states.
APPLIED RADIATION AND ISOTOPES
(2024)
Article
Oncology
Dominik Wawrzuta, Justyna Klejdysz, Marzanna Chojnacka
Summary: This study analyzed articles about radiation oncology published in The New York Times since its inception in 1851, and identified changes in media sentiment and prevalent themes related to radiotherapy. The findings suggest an increasing negative sentiment in media coverage towards radiotherapy, with a shift towards reporting treatment errors, toxicity, and ineffectiveness.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Sara Ronchi, Alessandro Cicchetti, Maria Bonora, Rossana Ingargiola, Anna Maria Camarda, Stefania Russo, Sara Imparato, Paolo Castelnuovo, Ernesto Pasquini, Piero Nicolai, Mohssen Ansarin, Michele Del Vecchio, Marco Benazzo, Ester Orlandi, Barbara Vischioni
Summary: This study evaluates the efficacy and toxicity of carbon ion radiotherapy (CIRT) in locally advanced head and neck mucosal melanoma patients. The results show that CIRT is safe and effective in treating the local region, and immunotherapy after relapse can improve overall survival. However, further prospective trials are needed to assess the role of targeted/immune- systemic therapy in this disease.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ping Wu, Lan Wu, Jing Ou, Jin-ming Cao, Mao-yong Fu, Tian-wu Chen, Erika Ouchi, Jiani Hu
Summary: This study aimed to develop CT radiomics models to preoperatively identify lymph node (LN) status in resectable esophageal squamous cell carcinoma (ESCC) patients. The results showed that the combined model, integrating ESCC and LN radiomics features with clinical features, had the highest predictive ability among the three models. The combined model's predictive ability was validated in both the test and external validation cohorts.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Computer Science, Artificial Intelligence
Xiangqiong Wu, Guanghua Tan, Hongxia Luo, Zhilun Chen, Bin Pu, Shengli Li, Kenli Li
Summary: This study develops a user-friendly framework for the automated diagnosis of thyroid nodules in ultrasound videos, simulating the diagnostic workflow of radiologists. By interpreting image characteristics and modeling temporal contextual information, the efficiency and generalizability of the diagnosis can be improved.
MEDICAL IMAGE ANALYSIS
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
L. Sorace, N. Raju, J. O'Shaughnessy, S. Kachel, K. Jansz, N. Yang, R. P. Lim
Summary: This study developed a deep learning model to assess the technical and inspiratory adequacy of anteroposterior chest radiographs. The model performed best for radiographs with adequate technique and worst for images with inadequate technique.
Article
Chemistry, Inorganic & Nuclear
Junyoung Lee, Geunsub Kim, Hyegang Chang, Sangmin Lee, Sung-Joon Ye
Summary: The study applied the convolution/superposition method to calculate the dose distribution of boron neutron capture therapy and compared it with the Monte Carlo method. The results showed that the C/S method has a fast calculation speed and reasonable accuracy.
APPLIED RADIATION AND ISOTOPES
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Devaki Shilpa Sudha Surasi, Praneeth Kalva, Ken-Pin Hwang, Tharakeswara Kumar Bathala
Summary: mpMR imaging is a valuable tool for diagnosing and staging prostate cancer, often superior to traditional methods. Standardized protocols aid in evaluating prostate mpMR imaging. Radiologists need to thoroughly study prostate imaging and be aware of potential pitfalls. Additional sequences can improve tumor detection sensitivity. This study emphasizes the importance of recognizing factors that complicate prostate MR imaging interpretation.
RADIOLOGIC CLINICS OF NORTH AMERICA
(2024)