Orthopedics

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Article Orthopedics

Learning Curve of Robotic-Assisted Total Knee Arthroplasty for a High-Volume Surgeon

Kevin B. Marchand, Joseph Ehiorobo, Kevin K. Mathew, Robert C. Marchand, Michael A. Mont

Summary: This study compares the operative times of robotic-assisted total knee arthroplasty (RATKA) at different time points and finds that the operative time continues to improve after the initial learning curve. The results demonstrate the importance of overcoming the initial complexity of a technology, which can lead to more effective and efficient procedures compared to traditional techniques.

JOURNAL OF KNEE SURGERY (2022)

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Article Clinical Neurology

A New Framework for Investigating the Biological Basis of Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: Mechanical Stress, Vulnerability and Time

Benjamin M. Davies, Oliver Mowforth, Aref-Ali Gharooni, Lindsay Tetreault, Aria Nouri, Rana S. Dhillon, Josef Bednarik, Allan R. Martin, Adam Young, Hitoshi Takahashi, Timothy F. Boerger, Virginia F. J. Newcombe, Carl Moritz Zipser, Patrick Freund, Paul Aarne Koljonen, Ricardo Rodrigues-Pinto, Vafa Rahimi-Movaghar, Jefferson R. Wilson, Shekar N. Kurpad, Michael G. Fehlings, Brian K. Kwon, James S. Harrop, James D. Guest, Armin Curt, Mark R. N. Kotter

Summary: This study aims to propose a new framework to support the investigation and understanding of the pathobiology of DCM. The results suggest that DCM should be considered as a function of multiple mechanical forces, alongside individual vulnerability and time.

GLOBAL SPINE JOURNAL (2022)

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Article Orthopedics

Current trends in the anterior cruciate ligament part II: evaluation, surgical technique, prevention, and rehabilitation

Volker Musahl, Ian D. Engler, Ehab M. Nazzal, Jonathan F. Dalton, Gian Andrea Lucidi, Jonathan D. Hughes, Stefano Zaffagnini, Francesco Della Villa, James J. Irrgang, Freddie H. Fu, Jon Karlsson

Summary: The clinical evaluation and management of ACL injury is a widely researched topic in orthopedic sports medicine. This study covers various aspects of clinical management such as evaluation, operative versus nonoperative management, and considerations in unique populations. It also discusses graft selection, rehabilitation, prevention, and reflects on the current state of ACL research and clinical management.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY (2022)

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Review Orthopedics

Mitochondrial quality control in cartilage damage and osteoarthritis: new insights and potential therapeutic targets

D. Liu, Z-J Cai, Y-T Yang, W-H Lu, L-Y Pan, W-F Xiao, Y-S Li

Summary: Osteoarthritis is a common joint disease characterized by pain, limited mobility, and decreased quality of life. Dysregulated mitochondrial quality control has been found to play a significant role in the pathogenesis and development of osteoarthritis. Maintaining mitochondrial quality control can help prevent and treat osteoarthritis.

OSTEOARTHRITIS AND CARTILAGE (2022)

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Review Primary Health Care

A quality assessment of YouTube content on shoulder instability

Christine M. Etzel, Steven L. Bokshan, Timothy A. Forster, Brett D. Owens

Summary: The study found that YouTube videos on shoulder instability are of low quality, accuracy, and reliability, highlighting the need for care providers to be cautious with information obtained from this platform.

PHYSICIAN AND SPORTSMEDICINE (2022)

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Review Orthopedics

What is the safe zone for transition of coronal alignment from systematic to a more personalised one in total knee arthroplasty? A systematic review

Benjamin L. Schelker, Andrej M. Nowakowski, Michael T. Hirschmann

Summary: The aim of this systematic review is to investigate whether alignment outside the safe zone of +/- 3 degrees in total knee arthroplasty (TKA) is associated with a higher revision rate and worse clinical outcome than alignment within this range. The results showed no significant differences in clinical outcomes and revision rates between implants positioned within +/- 3 degrees and those outside this range. However, further research is needed to determine the optimal alignment strategies and thresholds for different patient-specific alignment strategies.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY (2022)

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Article Orthopedics

Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration

Haoruo Jia, Xiao Lin, Dong Wang, Jingwei Wang, Qiliang Shang, Xin He, Kang Wu, Boyan Zhao, Pandi Peng, Han Wang, Di Wang, Pan Li, Liu Yang, Zhuojing Luo, Lei Yang

Summary: The study aims to develop a novel hydrogel with high injectability, biocompatibility and mechanical adaptability to the intervertebral disc environment, using a simple chemistry and method. The results show that the hydrogel has therapeutic effects on intervertebral disc degeneration and disc defect repair, demonstrating great translational potential for minimally invasive clinical treatment.

JOURNAL OF ORTHOPAEDIC TRANSLATION (2022)

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Editorial Material Orthopedics

Research Note: Thematic analysis in qualitative research

Julie Ayre, Kirsten J. McCaffery

JOURNAL OF PHYSIOTHERAPY (2022)

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Article Orthopedics

How Does Robotic-Arm Assisted Technology Influence Total Knee Arthroplasty Implant Placement for Surgeons in Fellowship Training?

Laura Y. Scholl, Emily L. Hampp, Kevin M. de Souza, Ta-Cheng Chang, Matthew Deren, Zachary C. Yenna, Nipun Sodhi, Michael A. Mont, Geoffrey H. Westrich

Summary: Implant malalignment can negatively affect postoperative outcomes in total knee arthroplasty. This study found that robotic-arm assisted TKA (RATKA) allowed for more accurate and precise implant positioning compared to manual techniques when performed by in-training orthopaedic surgical fellows. The results showed that fellows with limited RATKA experience were able to achieve similar accuracy and precision as experienced surgeons.

JOURNAL OF KNEE SURGERY (2022)

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Article Orthopedics

Incidence and Predictors of Prosthetic Joint Infection Following Primary Total Knee Arthroplasty: A 15-Year Population-Based Cohort Study

Anthony Bozzo, Seper Ekhtiari, Kim Madden, Mohit Bhandari, Michelle Ghert, Vickas Khanna, Gregory R. Pond, Mitchell J. Winemaker, Thomas Wood, Anthony Adili

Summary: The study found a decreasing trend in the risk of PJI following TKA. Most PJIs are diagnosed within 2 years postoperatively, but a small percentage continue to occur after 10 years. Factors such as male gender, younger age, and type II diabetes may increase the risk of PJI.

JOURNAL OF ARTHROPLASTY (2022)

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Article Clinical Neurology

Incidence, Risk, and Outcome of Pedicle Screw Loosening in Degenerative Lumbar Scoliosis Patients Undergoing Long-Segment Fusion

Lei Yuan, Xinling Zhang, Yan Zeng, Zhongqiang Chen, Weishi Li

Summary: This retrospective study aimed to investigate the incidence, risk factors, and outcomes of pedicle screw loosening in degenerative lumbar scoliosis (DLS) patients undergoing long-segment spinal fusion surgery. The results showed that screw loosening was common and tended to occur in the lowest instrumented vertebra (LIV) or uppermost instrumented vertebra (UIV). Risk factors for screw loosening included lateral subluxation >= 8 mm, osteopenia, osteoporosis, fusion to the sacrum, postoperative TLK greater than 10 degrees, and SVA imbalance.

GLOBAL SPINE JOURNAL (2023)

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Article Orthopedics

Evaluation of Therapeutic Effects of Quercetin Against Achilles Tendinopathy in Rats via Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Metalloproteinases

Halil Sezgin Semis, Cihan Gur, Mustafa Ileriturk, Fatih Mehmet Kandemir, Ozgur Kaynar

Summary: The study investigated the effects of quercetin against collagenase-induced tendinopathy, finding that collagenase injection triggers oxidative stress, inflammation, apoptosis, and autophagy, and activates MMPs, ICAM-1, and STAT3. Quercetin was able to reduce ICAM-1 levels, as well as exhibit antioxidant, anti-inflammatory, antiapoptotic, and antiautophagic effects, while also suppressing MMP expression in tendon tissues, demonstrating its protective properties against collagenase-induced tendon damage in rats.

AMERICAN JOURNAL OF SPORTS MEDICINE (2022)

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Article Clinical Neurology

Sarcopenia Is an Independent Risk Factor for Proximal Junctional Disease Following Adult Spinal Deformity Surgery

Ananth Eleswarapu, Daniel O'Connor, Flynn Andrew Rowan, Hai Van Le, Joseph B. Wick, Yashar Javidan, Roberto Rolando, Eric O. Klineberg

Summary: This study demonstrates that sarcopenia is an independent predictor of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) following adult spinal deformity surgery. Sarcopenia can be easily assessed on standard preoperative computed tomography or magnetic resonance imaging. Surgeons should include sarcopenia in preoperative risk assessment and consider measures to avoid PJF in sarcopenic patients.

GLOBAL SPINE JOURNAL (2022)

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Editorial Material Orthopedics

Machine learning and conventional statistics: making sense of the differences

Christophe Ley, R. Kyle Martin, Ayoosh Pareek, Andreas Groll, Romain Seil, Thomas Tischer

Summary: This editorial discusses the application of machine learning in orthopaedic surgery, addressing the differences between ML techniques and traditional statistics. It aims to familiarize readers with the new opportunities offered by the ML approach.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY (2022)

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Editorial Material Orthopedics

Artificial intelligence bot ChatGPT in medical research: the potential game changer as a double-edged sword

Jari Dahmen, M. Enes Kayaalp, Matthieu Ollivier, Ayoosh Pareek, Michael T. Hirschmann, Jon Karlsson, Philipp W. Winkler

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY (2023)

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Article Clinical Neurology

Association of Lumbar MRI Findings with Current and Future Back Pain in a Population-based Cohort Study

Richard Kasch, Julia Truthmann, Mark J. Hancock, Christopher G. Maher, Markus Otto, Christopher Nell, Niklas Reichwein, Robin Bulow, Jean-Francois Chenot, Andre Hofer, Georgi Wassilew, Carsten Oliver Schmidt

Summary: This population-based cohort study examined the associations between common lumbar degenerative changes observed on magnetic resonance imaging (MRI) and low back pain (LBP). The study found that there is no clinically important association between these degenerative findings and LBP, with most effects less than one unit on a 0 to 10 pain scale. Longitudinal studies on this topic are limited.

SPINE (2022)

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Article Orthopedics

Mesenchymal Stem Cell Exosomes Promote Functional Osteochondral Repair in a Clinically Relevant Porcine Model

Shipin Zhang, Keng Lin Wong, Xiafei Ren, Kristeen Ye Wen Teo, Hassan Afizah, Andre Boon Hwa Choo, Ruenn Chai Lai, Sai Kiang Lim, James Hoi Po Hui, Wei Seong Toh

Summary: This study validates the safety and efficacy of human mesenchymal stem cell (MSC) exosomes combined with hyaluronic acid (HA) for osteochondral repair in a clinically relevant micropig model. The results show that the combination treatment promotes functional cartilage and subchondral bone repair, with significantly improved morphological, histological, and biomechanical outcomes. No adverse response or major systemic alterations were observed, indicating the potential of this therapy for clinical applications.

AMERICAN JOURNAL OF SPORTS MEDICINE (2022)

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Article Primary Health Care

The effects of home confinement on physical activity level and mental status in professional football players during COVID-19 outbreak

Gurhan Donmez, Omer Ozkan, Yigitcan Menderes, Serife Seyma Torgutalp, Levend Karacoban, Nevzad Denerel, Savas Kudas

Summary: The study assessed the psychological impacts of lockdown and similar restrictions on professional football players during the coronavirus pandemic. Results showed that one fourth of the players completed the online survey, with the majority maintaining high physical activity levels. Correlations were found between marital status, walking activity, self-quarantine days, and mental health status of the players.

PHYSICIAN AND SPORTSMEDICINE (2022)

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Article Orthopedics

No difference between resurfaced and non-resurfaced patellae with a modern prosthesis design: a prospective randomized study of 250 total knee arthroplasties

Etienne Deroche, Cecile Batailler, John Swan, Elliot Sappey-Marinier, Philippe Neyret, Elvire Servien, Sebastien Lustig

Summary: The study found that there is no superiority of patellar resurfacing or non-resurfacing in terms of clinical or radiological outcomes at mid-term. Secondary patellar resurfacing is rare. There is not enough evidence to recommend systematic patellar resurfacing with a patella-friendly prosthesis.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY (2022)

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Review Orthopedics

The relation between the biochemical composition of knee articular cartilage and quantitative MRI: a systematic review and meta-analysis

K. S. Emanuel, L. J. Kellner, M. J. M. Peters, M. J. J. Haartmans, M. T. Hooijmans, P. J. Emans

Summary: This study aims to establish the relationship between quantitative magnetic resonance imaging (MRI) and biochemical concentration and organization in knee articular cartilage. The results show a significant correlation between delayed gadolinium-enhanced MRI of cartilage and proteoglycan concentration, while no correlation was found between T2 relaxation times and collagen concentration, but rather with organization.

OSTEOARTHRITIS AND CARTILAGE (2022)

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