Article
Obstetrics & Gynecology
Lasse Gronningsaeter, Mette-Elise Estensen, Helge Skulstad, Eldrid Langesaeter, Elisabeth Edvardsen
Summary: This study aimed to objectively study cardiorespiratory fitness and physical activity, and to evaluate the limiting factors of exercise intolerance after severe pre-eclampsia. The results showed significantly lower cardiorespiratory fitness and physical activity levels in patients who had severe pre-eclampsia. In addition, one third of the patients had cardiovascular limitations, highlighting the need for clinical follow-up and exercise interventions.
HYPERTENSION IN PREGNANCY
(2023)
Article
Obstetrics & Gynecology
Timothy Gesner, Joshua Fogel, Lennox Bryson
Summary: This study examined the use of blood pressure medication in preeclampsia patients and found that low-dose medication was associated with increased risk of readmission. It is recommended that clinicians consider the potential risk of readmission when reducing the dose of blood pressure medication.
HYPERTENSION IN PREGNANCY
(2023)
Review
Obstetrics & Gynecology
Minghui Ou, Futao Zhang, Shichao Cui, Shibo Zhao, Yan Yu
Summary: This study compared the efficacy of oral nifedipine and intravenous labetalol in the treatment of acute severe hypertension in pregnancy. The results showed no difference in systolic blood pressure, diastolic blood pressure, and adverse events between the two drugs. However, oral nifedipine achieved the target blood pressure faster and required a lower number of doses.
HYPERTENSION IN PREGNANCY
(2023)
Review
Obstetrics & Gynecology
Jie Tan, Huali Fei, Lumeng Chen, Xuhong Zhu
Summary: This meta-analysis aimed to investigate the relationship between hyperuricemia and maternal and neonatal complications in pregnant women. The results indicate a positive relationship between hyperuricemia and pregnancy-induced hypertension, preterm birth, low birth weight, and small gestational age.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Li Li, Jing Ping Sun, Rongyu Zuo, Yan Shen, Miao Zhao, Wanyu Zhao, Zhiling Luo
Summary: This study aimed to investigate myocardial deformation in fetuses with ventricular afterload increase using speckle tracking echocardiography. The results showed that fetuses with afterload increase had lower longitudinal strain and strain rate in the left ventricle and right ventricle, but left and right ventricular fractional shortening were normal.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Xin Lin, Ling-Ling Liu, Li-Juan Zheng, Chang-Yi Yang
Summary: This study analyzed the relationship between fetal middle cerebral artery (MCA) and umbilical artery (UA) blood flow indices or cerebroplacental ratio (CPR) and fetal outcomes, and described MCA and UA blood flow values across gestation. The results showed that MCA-resistance index (RI) (sensitivity: 70.1%, specificity: 64.3%) was the best index to predict fetal distress, and MCA-RI (sensitivity: 52.4%, specificity: 84.6%) was the best index to predict small for gestational age (SGA) during gestational age of 35-40 weeks. These findings are important for obstetricians to evaluate the status of singleton pregnancies.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
L. Angeli, S. Fieni, A. Dall'Asta, T. Ghi, S. De Carolis, S. Sorrenti, F. Rizzo, A. N. Della Gatta, G. Simonazzi, G. Pilu, M. Benvenuti, C. Luchi, T. Simoncini, N. Gaibazzi, G. Niccoli, D. Ardissino, T. Frusca
Summary: This study aimed to investigate the adherence to the ESC guidelines for mode of delivery in women with heart disease and its effect on maternal and neonatal outcomes in Italy. The results showed that deviating from the guidelines for planned cesarean delivery was associated with higher incidence of adverse neonatal outcomes, while there was no significant difference in adverse maternal outcomes between the two groups. Gestational age at delivery was found to be the only independent factor associated with the occurrence of adverse neonatal outcomes.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Hassan O. Eliwan, William R. G. Watson, Ashanty M. Melo, Lynne A. Kelly, Murwan Omer, Ali Jafar, Fiona M. O'Hare, Paul Downey, Eoghan E. Mooney, Amanda O'Neill, Alfonso Blanco, Irene Regan, Brian Philbin, Michelle O'Rourke, Beatrice Nolan, Owen Smith, Eleanor J. Molloy
Summary: This study aimed to investigate the response of neutrophils and monocytes in preterm infants to lipopolysaccharide (LPS) and activated protein C (APC) stimulation. Results showed that APC significantly reduced LPS-induced reactive oxygen intermediate (ROI) release from neutrophils. Monocyte ROI production in preterm infants was higher compared to adults and term controls. Neutrophil toll-like receptor 4 (TLR4) baseline expression was higher in term controls compared to preterm infants. Therefore, APC may reduce tissue damage in preterm infants by decreasing ROI release.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Yanna Zhou, Guipng Gan
Summary: This study analyzed the levels of TNF-alpha, DCN, and MAPK1 mRNA in the peripheral blood of patients with preeclampsia and their correlations. The results showed that TNF-alpha, DCN, and MAPK1 were highly expressed in the peripheral blood of patients with preeclampsia, especially in those with early-onset preeclampsia. The expression levels of DCN and MAPK1 were positively correlated with TNF-alpha levels.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Hailian Li, Haixiang Li, Xiaodan Li, Jing Wang, Pan Wang, Mingxia Zhao
Summary: This study explores the effects of preventive nursing based on quantitative evaluation on psychological state and maternal-infant outcome in patients with gestational diabetes mellitus (GDM). The results show that preventive nursing based on quantitative assessment can effectively control the blood glucose level of GDM patients, improve their degree of social support, resilience, coping style, and maternal-infant outcomes. This research provides a theoretical basis for the effective management of GDM patients in clinical work.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Letter
Obstetrics & Gynecology
John L. L. Frater
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Liping Qiu, Min Lv, Cheng Chen, Minmin Wang, Qiong Luo
Summary: This retrospective cohort study aimed to evaluate the clinical effects of emergency cervical cerclage in twin pregnancies with cervical dilation >= 1.0 cm in mid-trimester of gestation and to identify risk factors after cerclage. The results showed that emergency cervical cerclage can prolong gestation age and improve pregnancy outcomes compared with expectant management. Pre-operation WBC > 11.55 x 10(9)/L, CRP > 10.1, and cervical dilation >3.5 cm were identified as independent risk factors for delivery before 28 weeks after cerclage.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Gioia Mastromoro, Daniele Guadagnolo, Antonio Novelli, Barbara Torres, Maria Piane, Monia Magliozzi, Laura Bernardini, Flavia Ventriglia, Antonio Pizzuti, Simona Petrucci
Summary: This study describes a fetus with situs viscerum inversus and azygos continuation of the inferior vena cava, caused by previously unreported variants in compound heterozygosity in the CFAP53 gene, which is involved in cilial motility. Fetuses with laterality defects are suitable candidates for prenatal exome sequencing due to the high diagnostic rate of this group of anomalies. Timely molecular diagnosis is crucial for genetic counseling, providing information for couple decisions, recurrence risks, and predicting possible respiratory complications.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Manning Lang, Meiying Zhou, Ruobing Lei, Weihong Li
Summary: This study aimed to investigate the impact of IVF on pregnancy complications and birth outcomes in women of advanced maternal age. The results showed that the ART group had higher rates of primiparity, cesarean section, twin births, gestational hypertension, preeclampsia, and preterm birth. Neonates in the ART group had lower birth weights. However, in the singleton-only comparison, only gestational hypertension showed a statistically significant difference.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Review
Obstetrics & Gynecology
Jing Liu
Summary: Respiratory distress syndrome (RDS) is a common lung disease in newborn infants, especially premature infants, with high mortality. The traditional diagnosis and grading of RDS based on chest X-ray (CXR) findings may lead to misdiagnosis or delayed diagnosis. The use of ultrasound in the diagnosis of RDS is increasing and has achieved significant results in the management of RDS under lung ultrasound (LUS) monitoring.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Qiaoying Jiang, Zongda Jin, Wei Wang, Qiao Ji, Caixia Qi
Summary: This study aimed to analyze the effect of epidural analgesia on labor progress and pelvic floor muscle from the perspective of electromyography, and evaluate obstetric risk factors for dysfunction of pelvic floor muscle after vaginal delivery. The results showed that women who received epidural analgesia experienced a longer stage of labor, but it had no significant impact on the total score and pelvic floor muscle strength. Risk factors for pre-rest phase included maternal age, fetal weight, and length of the second stage, while fetal weight and length of the second stage were associated with the post-rest phase. Assessment of pelvic floor muscle function can guide better protection and reduce injury during pregnancy and childbirth.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
P. N. Ignatov, K. K. Neykova, T. Yordanova-Ignatova
Summary: Doppler velocimetry is a valuable tool in assessing pregnancy complications, and the ratio between middle cerebral artery and umbilical artery pulsatility indices is a more effective predictor of adverse perinatal and neonatal outcomes.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Pierre-Yves Robillard
Summary: This study aims to compare maternal-fetal morbidities between obese women with adequate, inadequate, and excessive gestational weight gain (GWG) based on the Institute of Medicine (IOM) 2009 recommendations. The results show that these IOM recommendations are mildly too high for obesity class I and obviously too high for obesity class II women.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Elisa Montaguti, Maria Cofano, Josefina Diglio, Marta Fiorentini, Anita Pellegrino, Jacopo Lenzi, Cesare Battaglia, Gianluigi Pilu
Summary: This study aimed to evaluate the relationship between maternal hemodynamics and pregnancy outcomes. It was found that both gestational hypertension/preeclampsia and fetal growth restriction were associated with increased uterine artery pulsatility index and significant differences in hemodynamic parameters. The uterine artery pulsatility index was found to be useful in predicting fetal growth restriction, while hemodynamic parameters were associated with the development of hypertensive disorders. Further research is needed to assess the value of hemodynamics evaluation in screening protocols of preeclampsia.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Matias Vaajala, Jeremias Tarkiainen, Rasmus Liukkonen, Ilari Kuitunen, Ville Ponkilainen, Maiju Kekki, Ville M. Mattila
Summary: This study aimed to investigate the incidence of traumatic brain injury (TBI) during pregnancy and its impact on pregnancy outcomes. The results showed that even mild TBI was associated with an increased rate of cesarean section (CS), especially during the third trimester. However, there was no evidence of difference in fetal outcomes, such as preterm birth, low birth weight, or need for intensive care unit.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
