Neurosciences

Article Behavioral Sciences

Comparisons are Odious? The neural basis of in-group and out-group social comparison among game players: An fMRI study

Zijie Fang, Hongwei Wen, Yuhong Zhou, Xuemei Gao

Summary: Social comparison is an important way for individuals to define their social characteristics. This study aimed to explore the activation of brain regions triggered by different social comparisons in game players and the moderating effect of group identity. The results showed that downward comparison activated different brain regions compared to upward comparison, and the moderating effect of group identity was not significant. Further functional connectivity analysis based on the brain region activation results was conducted.

BEHAVIOURAL BRAIN RESEARCH (2024)

Article Behavioral Sciences

Clinical effects of anodal tDCS and identifying response markers in post-traumatic stress disorder (PTSD): An open-label study

Mehdi Rezaei, Mohammad Mahdi Shariat Bagheri

Summary: This study examined the efficacy of tDCS for PTSD and related symptoms, as well as the factors that may predict response to tDCS. The results showed that tDCS had a positive effect in reducing symptoms of PTSD, depression, anxiety, and anhedonia. The severity of symptoms at baseline may also predict the response to tDCS.

BEHAVIOURAL BRAIN RESEARCH (2024)

Article Behavioral Sciences

Self-esteem and cortical thickness correlate with aggression in healthy children: A surface-based analysis

Huimin Wu, Yiqun Guo, Yaoyao Zhang, Le Zhao, Cheng Guo

Summary: Aggression can have serious consequences, but little is known about its personality and neurological origins in children. This study investigated the relationship between self-esteem, aggression, and brain structure in healthy children, and found that self-esteem was negatively associated with aggression. The study also revealed that increased cortical thickness in certain brain areas may be a potential mechanism linking low self-esteem to aggression in children.

BEHAVIOURAL BRAIN RESEARCH (2024)

Article Clinical Neurology

Early life interpersonal stress and depression: Social reward processing as a potential mediator

Esther E. Palacios-Barrios, Kunal Patel, Jamie L. Hanson

Summary: This review examines the association between early life interpersonal stress (ELIS) and depression, as well as the underlying mechanisms. The research shows that ELIS affects how youth respond to social rewards, and similar impairments in social reward processing are observed in youth with depression. The authors propose a preliminary model that suggests neurobehavioral disruptions in social reward processing as a mediating factor in the connection between ELIS and depression.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Gamma oscillations in the mPFC: A potential predictive biomarker of depression and antidepressant effects

Yong-Yu Yin, Jiao-Zhao Yan, Shi-Xin Lai, Qian-Qian Wei, Si-Rui Sun, Li-Ming Zhang, Yun-Feng Li

Summary: This study found that gamma oscillations are closely associated with depression and may serve as predictive biomarkers of depression. Chronic restraint stress and lipopolysaccharide induced significant depression-like behaviors in mice and reduced gamma oscillations in the medial prefrontal cortex. Administration of ketamine, scopolamine, or fluoxetine increased gamma oscillations and exhibited rapid-acting antidepressant effects.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Transdiagnostic cognitive biases in psychiatric disorders: A systematic review and network meta-analysis

Katie M. Lavigne, Jiaxuan Deng, Delphine Raucher-Chene, Adele Hotte-Meunier, Chloe Voyer, Lisa Sarraf, Martin Lepage, Genevieve Sauve

Summary: Psychiatric disorders are characterized by cognitive deficits and cognitive biases, which are associated with specific symptoms. While cognitive biases are present across diagnoses, their severity varies.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Associations of maternal prenatal psychological symptoms and saliva cortisol with neonatal meconium microbiota: A cross-sectional study

Nadia Deflorin, Ulrike Ehlert, Rita T. Amiel Castro

Summary: Changes in the gut microbiome of infants have been associated with maternal psychological symptoms during pregnancy. This study found that maternal prenatal depressive symptoms are associated with lower diversity of the infant's microbiome, while maternal saliva cortisol levels are linked to increased diversity and changes in specific bacterial groups. Further research is needed to understand the implications of these microbiota alterations for child health.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Association between suicidal behavior and impaired glucose metabolism in first-episode drug-naive patients with schizophrenia

Zheng Ma, Hui-Xia Zhou, Da-Chun Chen, Dong-Mei Wang, Xiang-Yang Zhang

Summary: The impaired glucose metabolism in drug-na & iuml;ve schizophrenia patients is strongly associated with suicidal behavior, suggesting that glucose metabolism abnormalities may be potential biomarkers of suicide in schizophrenia patients. Regular monitoring of glucose metabolism variables is essential for suicide prevention.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Transcriptomic analyses of rats exposed to chronic mild stress: Modulation by chronic treatment with the antipsychotic drug lurasidone

Veronica Begni, Moira Marizzoni, Kerstin Camile Creutzberg, Diana Morena Silipo, Mariusz Papp, Annamaria Cattaneo, Marco Andrea Riva

Summary: Exposure to stressful experiences is a significant risk factor for mental disorders, and pharmacological interventions targeting stress-induced alterations can help restore brain function. Lurasidone, an antipsychotic drug, has been shown to normalize the impairments caused by stress exposure and could be a valuable treatment for stress-induced mental illnesses. However, the mechanisms underlying the therapeutic effects of lurasidone are not well understood. This study found that chronic lurasidone treatment counteracted some of the transcriptional changes induced by chronic mild stress exposure, providing new insights into the potential therapeutic effects of lurasidone.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Behavioral Sciences

Effects of reproductive status on behavioral and neural responses to isolated pup stimuli in female California mice

Kerianne M. Wilson, April M. Arquilla, Manal Hussein, Kelsey M. Rosales-Torres, May G. Chan, Wendy Saltzman

Summary: The transition to motherhood in mammals involves changes in females' perception and responsiveness to sensory stimuli from infants. This study examined the effects of reproductive status on behavioral responses and brain activity in California mice. The results showed that reproductive status influenced females' behavioral responses to pup stimuli, particularly odors, and inhibited defense circuitry in response to pup stimuli.

BEHAVIOURAL BRAIN RESEARCH (2024)

Article Behavioral Sciences

Enhancing fentanyl antinociception and preventing tolerance with α-2 adrenoceptor agonists in rats

Deniz Yildiz Pehlivan, Ali Yucel Kara, Ahmet Koyu, Fatma Simsek

Summary: This study examines the effects of alpha-2 adrenoceptor agonists on fentanyl tolerance and antinociception, and suggests that combined drugs can prevent tolerance and enhance fentanyl's pain-relieving effects. The findings have promising implications for chronic pain management.

BEHAVIOURAL BRAIN RESEARCH (2024)

Article Neurosciences

Daily methocinnamox treatment dose-dependently attenuates fentanyl self-administration in rhesus monkeys

David R. Maguire, Charles P. France

Summary: Methocinnamox (MCAM) is a novel, long-acting opioid receptor antagonist that effectively decreases fentanyl self-administration and prevents opioid overdose in monkeys. The study demonstrates the potential therapeutic utility of MCAM in the treatment of opioid use disorder.

NEUROPHARMACOLOGY (2024)

Article Neurosciences

Mitochondrial malfunction mediates impaired cholinergic Ca2+signalling and submandibular salivary gland dysfunction in diabetes

Olga Kopach, Tetyana Pivneva, Nataliya Fedirko, Nana Voitenko

Summary: This study found that diabetic animals exhibit severe xerostomia characterized by reduced saliva flow rate, diminished total protein content, and decreased amylase activity. The impaired saliva production in diabetes is associated with reduced and delayed intracellular Ca2+ signals in submandibular acinar cells, caused by malfunctioning mitochondria. Targeting malfunctioning mitochondria may be a potential strategy for the treatment of diabetic xerostomia.

NEUROPHARMACOLOGY (2024)

Article Neurosciences

Exploring functional connectivity alterations in sudden sensorineural hearing loss: A multilevel analysis

Jing Li, Yan Zou, Xiangchuang Kong, Yangming Leng, Fan Yang, Guofeng Zhou, Bo Liu, Wenliang Fan

Summary: This study examines the functional connectivity changes in individuals with sudden sensorineural hearing loss (SSNHL) at the integrity, network, and edge levels. The findings reveal reduced intranetwork connectivity strength and increased internetwork connectivity in SSNHL patients. These alterations are associated with the duration of SSNHL and Tinnitus Handicap Inventory scores. The study provides crucial insights into the neural mechanisms of SSNHL and the brain's network-level responses to sensory loss.

BRAIN RESEARCH (2024)

Article Neurosciences

CREB-induced LINC00473 promotes chemoresistance to TMZ in glioblastoma by regulating O6-methylguanine-DNA-methyltransferase expression via CEBPα binding

Li-Ya Jiang, Guan-Hao Wang, Jing-Jiao Xu, Xiao-Li Li, Xiao-Yan Lin, Xiang Fang, Hong-Xu Zhang, Mei Feng, Chun-Ming Jiang

Summary: This study reveals the importance of LINC00473 in regulating temozolomide (TMZ) resistance in glioblastoma (GB) and its potential mechanism. By regulating the expression of CEBP alpha and MGMT, LINC00473 promotes the formation of chemoresistance. Furthermore, LINC00473 can transfer chemoresistance to adjacent sensitive cells through exosomes.

NEUROPHARMACOLOGY (2024)

Article Neurosciences

Imaging of Childhood Cerebral Vasculitis

Sheng-Che Hung, Carolina Guimaraes

NEUROIMAGING CLINICS OF NORTH AMERICA (2024)

Article Neurosciences

Imaging of Drug-Related Vasculopathy

Paulo Puac-Polanco, Alex Rovira, Lubdha M. Shah, Richard H. Wiggins, Francisco Rivas Rodriguez, Carlos Torres

Summary: Cocaine-induced CNS vasculitis and midline destructive lesion, as well as reversible vasoconstriction syndrome triggered by substance abuse, are all important conditions that are associated with drugs and their risk factors.

NEUROIMAGING CLINICS OF NORTH AMERICA (2024)

Article Behavioral Sciences

The temporal dynamics of how the brain structures natural scenes

Astrid Prochnow, Xianzhen Zhou, Foroogh Ghorbani, Paul Wendiggensen, Veit Roessner, Bernhard Hommel, Christian Beste

Summary: Individuals organize events in their environment by partitioning them into discrete units. This study reveals that the neural activity in the brain plays a critical role in this process, reflecting the key elements of event segmentation.

CORTEX (2024)

Review Behavioral Sciences

Revealing the confusion of the evolution of the term sagittal stratum. Historical overview and systematic literature review

Beste Gulsuna, Abuzer Gungor, Alp O. Borcer, Ugur Ture

Summary: The fiber dissection technique has been used to study the internal structures of the brain, with less focus on white matter. The sagittal stratum, a white matter structure, has not received enough attention and has been a subject of controversy. Recent studies suggest potential functions of the sagittal stratum, emphasizing the importance of understanding this structure accurately.

CORTEX (2024)

Review Linguistics

Anatomo-functional profile of white matter tracts in relevance to language: A systematic review

Yasin Kargar, Milad Jalilian

Summary: This article provides a systematic review of how the brain processes language and the functions of white matter tracts related to language. It offers valuable guidance for neuroclinicians and neurosurgeons in diagnosing language impairments and planning treatments.

JOURNAL OF NEUROLINGUISTICS (2024)