Article
Medicine, General & Internal
Xin Liang, Fei Guo, Xiaoce Cai, Jiao Wang, Jiale Chen, Li Liu, Yan Chen, Fang Liu, Yuhua Du, Lei Li, Xin Li
Summary: This study aimed to clarify the relationship between vitiligo and sexual dysfunction. It found that patients with vitiligo were at greater risk of sexual dysfunction, with a stronger association observed in women than in men.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Martta Kerkela, Mika Gissler, Tanja Nordstrom, Olavi Ukkola, Juha Veijola
Summary: This study examined the association between participation in the longitudinal follow-up study and cardiometabolic disorders. The results showed that participation in the study may have a weak positive health effect among men.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Feng Xu, Qingtong Zhang, Dongsheng Xuan, Shuai Zhao, Yafeng Wang, Linlin Han, Shiqian Huang, Hongyu Zhu, Tingting Wang, Xiangdong Chen
Summary: This study found that daytime variation may affect recovery after general anesthesia, and afternoon surgery may provide better protection compared to morning surgery.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Fateen Ata, Adeel Ahmad Khan, Ibrahim Khamees, Phool Iqbal, Zohaib Yousaf, Bayan Z. M. Mohammed, Reham Aboshdid, Sandy K. K. Marzouk, Haidar Barjas, Madiha Khalid, Ihab El Madhoun, Mohammed Bashir, Anand Kartha
Summary: This study aimed to identify predictors of hospital length of stay (LOS), readmission, and recurrence in diabetic ketoacidosis (DKA) patients. The results showed that gender, new-onset DM, higher comorbidity index, lower levels of hemoglobin, sodium, and potassium, higher levels of urea, longer DKA duration, and admission to MICU were predictors of longer hospital LOS. None of the factors were significantly associated with 90-day readmission. Patients with pre-existing type 1 diabetes were more likely to have a six-month DKA recurrence compared to pre-existing type 2 diabetes. Consultation with a diabetes educator at the index admission was associated with decreased odds of recurrence.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Chunlong Yan, Dengfeng Tian, Chenhong Zhang, Qiang Zhang, Yanqiu Sun
Summary: This study aimed to explore the changes in blood cellular and biochemical parameters of rats in a natural environment of low pressure and low oxygen on the plateau. The results showed that under high-altitude environment, the rats' red blood cells and blood biochemical indicators changed, with improved oxygen carrying capacity, possibly reduced disease resistance, affected coagulation and hemostasis functions, and potential impact on liver function, renal function, heart function, and skeletal muscle energy metabolism.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Tobias Wibble, Tony Pansell
Summary: The purpose of this study was to construct and validate a Swedish translation (VVAS-S) of the Visual Vertigo Analogue Scale (VVAS). The translation process involved two authors translating the original English version into Swedish, which was then back-translated by an independent professional translator. The translated version was found to be comparable to the original in terms of internal reliability and was perceived as easy to implement by participants, making it suitable for clinical use in a Swedish-speaking setting.
ANNALS OF MEDICINE
(2023)
Review
Medicine, General & Internal
Wei He, Fang He, Huixian Hu
Summary: This study assessed the efficacy and safety of VEN-based treatments in relapsed or refractory multiple myeloma patients. The results showed that VEN treatment achieved meaningful responses in terms of ORR, CR, VGPR, and PR. Furthermore, multi-drug treatments were more effective than VEN +/- Dex treatments, and patients with t(11;14) translocation or high BCL-2 expression showed better response to VEN treatment.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Chia-Wen Lu, Kuen-Cheh Yang, Yu-Chiao Chi, Tsan-Yu Wu, Chien-Hsieh Chiang, Hao-Hsiang Chang, Kuo-Chin Huang, Wei-Shiung Yang
Summary: Lean non-alcoholic fatty liver disease (NAFLD) is similar to overweight NAFLD and should be detected early. The adiponectin-leptin ratio (AL ratio) may serve as a reliable marker for early detection of lean NAFLD independent of insulin resistance.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Chaojin Chen, Bingcheng Chen, Jing Yang, Xiaoyue Li, Xiaorong Peng, Yawei Feng, Rongchang Guo, Fengyuan Zou, Shaoli Zhou, Ziqing Hei
Summary: Postoperative sepsis is a significant cause of mortality after liver transplantation. Our study developed a predictive model for postoperative sepsis in liver transplant recipients using machine learning. The Random Forest Classifier model showed the best performance, assisting in clinical decision-making.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Xingyu Chang, Yaqi Wang, Yi Liu, Yanyu Shen, Jiaqing Feng, Qianqian Liu, Chenjun Jiang, Jing Yu, Xulei Tang, Gaojing Jing, Qianglong Niu, Songbo Fu
Summary: This study analyzed the prevalence of subclinical hypothyroidism (SCH) in the pre-diabetic population and found a significant deviation in the diagnosis of SCH in the elderly. The prevalence of SCH was higher in females and the impaired fasting glucose population. However, age-related factors need to be further investigated.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Mingyu Hao, Xiaohong Huang, Xueting Liu, Xiaokang Fang, Haiyan Li, Lingbo Lv, Liming Zhou, Tiecheng Guo, Dewen Yan
Summary: This study developed a new nomogram model based on clinical parameters to predict diastolic cardiac dysfunction in patients with Type 2 diabetes mellitus (T2DM). The model included age, body mass index (BMI), triglyceride (TG), creatine phosphokinase isoenzyme (CK-MB), serum sodium (Na), and urinary albumin/creatinine ratio (UACR) as predictors. The model showed good predictive performance and can serve as a reliable tool for large-scale epidemiological studies and early screening of T2DM patients with cardiac complications.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Youping Zhou, Youlin Deng, Jing Wang, Zhengjian Yan, Qiang Wei, Jixing Ye, Junhui Zhang, Tong-Chuan He, Min Qiao
Summary: In this study, it was found that monensin effectively inhibits cell proliferation, migration, and cell cycle progression, while inducing apoptosis and G1 arrest in human colorectal cancer cells. Monensin targets multiple cancer-related signaling pathways, including the IGF1R signaling pathway, by increasing IGF1 expression and suppressing IGF1R expression. These findings suggest that monensin has the potential to be repurposed as an anti-colorectal cancer agent. Further investigation is needed to understand the detailed mechanisms underlying its anti-cancer effects.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Sung-Eun Choi, Dong-Jin Park, Ji-Hyoun Kang, Shin-Seok Lee
Summary: This study found that in Korean patients with biopsy-proven lupus nephritis, those who had simultaneous positivity for anti-dsDNA, nucleosome, and histone antibodies (3-pos) had higher disease activity and worse renal histopathology, and were more prone to experience a rapid decline in renal function.
ANNALS OF MEDICINE
(2023)
Article
Medicine, General & Internal
Nevena Vidovic, Marija Knez, Marija Ranic, Fathia Faid, Dragana Jovic, Marija Glibetic, Marija Takic
Summary: This study investigated the sphingolipid content in the erythrocyte membrane of Libyan migrant and Serbian resident women, and found lower levels of sphingolipids and cholesterol in Libyan emigrants compared to Serbian residents. Additionally, the study found an inverse correlation between erythrocyte sphingolipid content and Omega-3 index, and a positive correlation with vitamin D status and membrane cholesterol levels. The study suggests that erythrocyte sphingolipid levels could serve as an additional biomarker of cardiovascular health, but further research in a larger population is needed.
LIBYAN JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Enyereibe Chuks Ajare, Francis Chukwuebuka Campbell, Emeka K. Mgbe, Aghogho O. Efekemo, Augustine Chukwudi Onuh, A. O. Nnamani, Okwuoma Okwunodulu, Samuel C. Ohaegbulam
Summary: This study aims to measure the corpus callosum (CC) dimensions in the adult population of southeast Nigeria, providing reference ranges for CC-related pathologies. Using cranial MRI, the mean length and height of the CC were determined to be 75.58mm and 24.64mm, respectively, with variations in width dimensions in different regions.
LIBYAN JOURNAL OF MEDICINE
(2023)
Letter
Medicine, General & Internal
Amnuay Kleebayoon, Viroj Wiwanitkit
LIBYAN JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Yoo Jung Park, Kwon Hui Seo, Jin Deok Joo, Hong Soo Jung, Yong Shin Kim, Ji Yung Lee, Hunwoo Park
Summary: This study investigated the effects of Etomidate on the expression and release of high-mobility group box 1 (HMGB1) in septic rats and found that Etomidate can inhibit the release and expression of HMGB1, which may be associated with its inhibitory effects on pro-inflammatory cytokine release and NF-kappa B activity.
LIBYAN JOURNAL OF MEDICINE
(2023)
Article
Primary Health Care
Joanna Peart, Nele R. Michels, Karena Hanley, Cian Dolan, Julie Luyckx, Valerie Tanghe, Emma Peeters, Milda Burneikaite, Sonata Varvuolyte, Vesna Homar, Lucija Galic, Kamala Klobucar Kragelj, Geoff McCoombe, Nynke Scherpbier
Summary: This study investigates the views of GP trainees from Belgium, Ireland, Lithuania, and Slovenia on how their hospital experience contributes to their professional development as a GP. The study finds that despite additional challenges, the hospital rotation component of GP training is valued by trainees. The study highlights the need to ensure that learning from the hospital placements is placed firmly in the context of general practice.
EUROPEAN JOURNAL OF GENERAL PRACTICE
(2023)
Article
Economics
Hussain A. Al-Omar, Nasser Aljehani, Ali Alshehri, Abdullah Al-Khenizan, Faisal Al-Shammari, Abdulmohsen Abanumay, Volker Schnecke, Joao L. Carapinha, Saleh A. Alqhatani
Summary: This study aimed to estimate the 10-year cost-consequence of weight loss on obesity-related outcomes in a sample of privately insured adults with obesity in Saudi Arabia (KSA). The findings showed that moderate weight loss of 5-15% over 10 years is associated with substantial cost savings, and prevented incidence cases of obesity-related outcomes. This could help policymakers implement weight loss programs in KSA.
JOURNAL OF MEDICAL ECONOMICS
(2023)
Article
Economics
Catherine M. Lockhart, Cara L. McDermott, Aaron B. Mendelsohn, James Marshall, Ali McBride, Gary Yee, Minghui Sam Li, Aziza Jamal-Allial, Djeneba Audrey Djibo, Gabriela Vazquez Benitez, Terese A. DeFor, Pamala A. Pawloski
Summary: This study developed an algorithm based on claims data to identify cancer patients and chemotherapy regimens for a comparative effectiveness analysis of G-CSF use. The initial algorithm underestimated the number of patients receiving chemotherapy, but by modifying the criteria, the final algorithm successfully identified 886 patients who received G-CSF.
JOURNAL OF MEDICAL ECONOMICS
(2023)
