Integrative & Complementary Medicine

99.8K Papers

Follow See full results

Article Plant Sciences

Bioactive metabolites reveal the therapeutic consistency of epimedii folium from multi-plant sources for the treatment of kidney-yang deficiency

Xinguang Sun, Yingfei Li, Juan Li, Haizhen Liang, Jie Zhang, Xiaojuan Chen, Qi Li, Xu Pang, Qianzhi Ding, Juan Song, Baolin Guo, Baiping Ma

Summary: This study aimed to investigate the underlying reasons for the similar pharmacological effects of Epimedii Folium from two botanical sources, Epimedium koreanum and Epimedium wushanense. The results showed that both plant species exhibited similar effects on promoting mating behaviors and testosterone levels in rats. The study also found that Epimedii Folium can regulate testosterone production by reversing expressions of key steroidogenic enzymes in rat Leydig cells.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Efficacy of Trigonella foenum-graecum Linne in an animal model of particulate matter-induced asthma exacerbation

Eun-Young Kim, Hoyeon Park, Eom Ji Kim, Seung Hoon Lee, Jun Won Choi, Jonghyun Kim, Hyuk-Sang Jung, Youngjoo Sohn

Summary: This study demonstrates the efficacy of Trigonella foenum-graecum Linne (TFG) in alleviating PM-induced inflammatory response in bronchial epithelial cells and an animal model of asthma exacerbation.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Revealing the improvement of diabetes by Si Wei Jiang Huang Tang San through ERK/HIF1α signaling pathway via network pharmacology

Tianshu Xu, Ping He, So Namwangdu, Chunyang Xu, Biyu Hou, Peng Ma, Zijing Wang, Li Zhang, Guanhua Du, Tse Ring, Tengfei Ji, Guifen Qiang

Summary: Residents in Urumqi region are warned to prepare for heavy rain that may cause floods and mudslides, and take measures to reduce possible losses.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Chemical profiling of Shengmai injection, tissue distribution and pharmacokinetic characteristics of ginsenosides after intravenous dosing Shengmai injection in rats with cerebral ischemia

Huanhuan Wang, Liying Tang, Shaowei Hu, Xixian Kong, Yi Ouyang, Dong Zhang, Yi Zhang, Shihuan Tang, Hongwei Wu, Hongjun Yang

Summary: This study revealed the ingredients, tissue distribution, and pharmacokinetic characteristics of Shengmai injection (SMI). The study found that ginsenosides were the main active compounds in SMI and had high exposure in different tissues. The pharmacokinetic evaluation showed different elimination rates for different types of ginsenosides.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

An integrated strategy for rapid discovery and identification of the potential effective fragments of polysaccharides from Saposhnikoviae Radix

Jie Li, Chang Zhou, Shu-jin Jing, Yan-yan Jiang, Bin Liu

Summary: This study explored the activity of degraded polysaccharides in Saposhnikoviae Radix and identified potential effective fragments. By establishing chromatographic fingerprints using HPLC and evaluating immunomodulatory activity, the study screened out potential effective fragments based on spectrum-effect relationship analysis. Using LC-IT-TOF MS, the chemical structure of these fragments was elucidated. This study provides an experimental foundation for the exploration of active fragments from macromolecular components.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Zhisou powder displays therapeutic effect on chronic bronchitis through inhibiting PI3K/Akt/HIF-1α/VEGFA signaling pathway and reprograming metabolic pathway of arachidonic acid

Yahui Dong, Yang Liu, Jie Tang, Jiahui Du, Xuzhen Zhuang, Song Tan, Ye Yang, Dengke Yin

Summary: This study aimed to explore the potential mechanism of Zhisou Powder in the treatment of chronic bronchitis by combining UPLC-Q-Exactive-Orbitrap-MS, network pharmacology, metabonomics, and experiment verification.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Jianpi Shengqing Huazhuo Formula improves abnormal glucose and lipid metabolism in obesity by regulating mitochondrial biogenesis

Wenkai Wang, Shanshan Chen, Shuting Xu, Guangyi Liao, Weihao Li, Xiao Yang, Tingting Li, Huifen Zhang, Huanhuan Huang, Yuqing Zhou, Huafeng Pan, Chuanquan Lin

Summary: JSH has been found to have a good effect on obese patients with early abnormal glucose and lipid metabolism. It can reduce body weight, improve glucose and lipid metabolism, and alleviate liver damage in both clinical observations and animal experiments.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Characterization of the glucuronidating pathway of pectolinarigenin, the major active constituent of the Chinese medicine Daji, in humans and its influence on biological activities

Peiqi Liu, Qian Li, Guanghao Zhu, Tiantian Zhang, Dongzhu Tu, Feng Zhang, Moshe Finel, Yuqi He, Guangbo Ge

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Review Plant Sciences

Review of traditional uses, phytochemistry and pharmacology of Tibetan Medicine tangchong

Tianru Wang, Qiuyue Li, Ziyu Zhou, Jia Liu, Yiwen Tao, Yi Zhang, Yong Zeng, Sanyin Zhang, Jinsong Su

Summary: This review provides a comprehensive analysis of tangchong, a group of plants from the Solanaceae family used in traditional Tibetan medicine. It summarizes the traditional usage, chemical composition, pharmacology, toxicology, and quality control measures of these plants. The review highlights the significant value of tangchong as an ethnomedicinal resource, with pharmacological activities primarily linked to its alkaloid content.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Kinsenoside from Anoectochilus roxburghii (Wall.) Lindl. suppressed oxidative stress to attenuate aging-related learning and memory impairment via ERK/Nrf2 pathway

Yu Xiao, Changsong Duan, Pushuang Gong, Qi Zhao, Xin hui Wang, Fang Geng, Jin Zeng, Tianfeng Luo, Yisha Xu, Junning Zhao

Summary: This study explored the protective property of aqueous extract of Anoectochilus roxburghii on aging and aging-related learning and memory impairment. The findings showed that the extract alleviated low growth rate, abnormal brain, liver, and thymus indexes, and decline in learning and memory capability of aging mice.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Essential oil from Inula japonica Thunb. And its phenolic constituents ameliorate pulmonary injury and fibrosis in bleomycin-treated mice

Fan Wei, Yuzhen Yin, Jie Li, Yibo Chang, Shuyuan Zhang, Wenyu Zhao, Xiaochi Ma

Summary: Inula japonica essential oil (EOI) shows potential therapeutic effects on pulmonary injury and fibrosis in mouse models. EOI can inhibit inflammatory response, regulate redox equilibrium, and suppress pulmonary fibrosis by mediating the TGF-beta/Smad and PI3K/Akt signaling pathways.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

High-resolution neuraminidase inhibition profiling of Arnebia euchroma (Royle) IM Johnst. based on HR-MS and target isolation: An example study of anti-infectious constituents in traditional Chinese medicine

Yuheng Huang, Xiaoxin Guo, Zhen Wang, Cong Yin, Mu Chen, Jiaming Xie, Ning Li, Zhengchao Tu, Juan Li, Jiaqing Cao, Zhengjin Jiang, Weihuan Huang, Haiyan Tian

Summary: Arnebia euchroma, a traditional Chinese medicine, has potential inhibitory activities on bacterial and viral neuraminidases, making it a promising candidate for anti-infectious drugs. Through high-resolution bioassay profiling, potential active ingredients in A. euchroma were identified and their inhibitory activities on neuraminidases were determined.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Identification of bioactive components on antihemorrhoidal activity of Cistus laurifolius L. using RP-HPLC and LC-QTOF-MS

Sultan Pekacar, Burgin Ozuepek, Esra Kuepeli Akkol, Hakki Tastan, Halil Ersan, Didem Deliorman Orhan

Summary: C. laurifolius is widely used in folk medicine in Anatolia and has been found to possess anti-inflammatory and anti-hemorrhoidal properties.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Xingbei antitussive granules ameliorate cough hypersensitivity in post-infectious cough guinea pigs by regulating tryptase/PAR2/ TRPV1 pathway

Yun Li, Ruiheng Zhao, Mengyuan Zhang, Kunlu Shen, Xin Hou, Bowen Liu, Chunxiao Li, Bingqing Sun, Min Xiang, Jiangtao Lin

Summary: This study demonstrates the significant therapeutic effects of Xingbei antitussive granules (XB) on post-infectious cough (PIC). XB treatment alleviates cough hypersensitivity and inflammatory responses, inhibits the degranulation of mast cells, and ameliorates neurogenic inflammation in PIC guinea pigs. The mechanisms may be associated with the inhibition of Tryptase/PAR2/PKC/TRPV1 and the recovery of respiratory bacterial microbiota.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Safety and antidiabetic activity of Lagenaria siceraria (Molina) Standl. juice in streptozotocin-induced diabetic rats

Manas Jyoti Das, Dipanjan Banerjee, Amartya Banerjee, Sangita Muchahary, Archana Sinha, Debananda Gogoi, Pronobesh Chattopadhyay, Suman Dasgupta, Sankar Chandra Deka

Summary: Lagenaria siceraria (Molina) Standl. Juice has demonstrated promising anti-inflammatory properties as well as the capacity to inhibit the digestion enzymes glucosidase and amylase, opening new avenues for further research into its antidiabetic potential.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Total Glucosides of White Paeony Capsule ameliorates Parkinson's disease-like behavior in MPTP-induced mice model by regulating LRRK2/ alpha-synuclein signaling

Hong-Yan Li, De-Shui Liu, Li-Bo Li, Ying-Bo Zhang, Hai-Ying Dong, Jing-Yan Zhang, Jun-Ping Wang, Ming Jin, Nan Luo, Xiao-Jie Zhang

Summary: This study found that the Total Glucosides of White Paeony Capsule (TGPC) exhibited neuroprotective effects on a mice model of Parkinson's disease (PD). The neuroprotective effects were associated with the prevention of neuroinflammation and neurodegeneration modulated by the LRRK2/alpha-synuclein (alpha-syn) pathway.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Integrated analysis of metabolomic and transcriptomic profiling reveals the effect of Atractylodes oil on Spleen Yang Deficiency Syndrome in rats

Xin Zhan, Yangxin Xiao, Qipan Jian, Yan Dong, Chang Ke, Zhongshi Zhou, Yanju Liu, Jiyuan Tu

Summary: The study demonstrates that Atractylodes oil (AO) can improve the symptoms of Spleen Yang Deficiency Syndrome (SYDS) in rats, and its mechanism of action may be related to the activation of the AMPK/SIRT1/PGC-1 alpha signaling pathway.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Review Plant Sciences

Erythrina velutina Willd.: A review of its traditional uses, phytochemistry, pharmacology, and toxicology

Tomi Lois Adetunji, Marvellous Amarachi Acho, Victory Oghenetega Samuel, Chinemerem Ruth Ohoro, Mmbulaheni Ramulondi

Summary: The traditional medicinal uses of Erythrina velutina, combined with modern scientific research, highlight its pharmacological potential and make it a significant candidate for drug development.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

A systematical strategy for quality markers screening of different methods processing Platycodonis radix based on phytochemical analysis and the impact on Chronic Obstructive Pulmonary Disease

Tingting Bai, Jingying Guo, Yaling Deng, Yuqing Zheng, Jie Shang, Peng Zheng, Minmin Liu, Ming Yang, Jinlian Zhang

Summary: This study evaluated the phytochemical composition and pharmacodynamics of Platycodon grandiflorum (PG) and Baihezhijiegeng (BJ). The results showed that BJ has anti-COPD activity by regulating inflammatory mediators and the EGFR/MUC5AC pathway in rats with COPD.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

Article Plant Sciences

Traditional Chinese medicine for neonatal hypoxic-ischemic encephalopathy: A Bayesian network meta-analysis

Chao Zhang, Jiajia Guo, Huaiqing Yin, Chongjuan Yin, Yurong Peng

Summary: This study conducted a network meta-analysis to investigate the efficacy of Chinese herbal injections (CHIs) combined with traditional symptomatic treatment (TST) for neonatal hypoxic-ischemic encephalopathy (HIE). The results showed that CHIs combined with TST significantly improved treatment performance compared to TST alone, with SXI + TST showing the most preferable improvement.

JOURNAL OF ETHNOPHARMACOLOGY (2024)

添加到收藏夹

«
1
2
3
4
5
»

See full results

Related Categories

Anesthesiology (212.5K) Audiology & Speech-Language Pathology (1.7K) Clinical Neurology (1.3M) Critical Care Medicine (338.4K) Dentistry, Oral Surgery & Medicine (340.8K) Dermatology (413.6K) Emergency Medicine (142.9K) Endocrinology & Metabolism (751.7K) Gastroenterology & Hepatology (856.4K) Geriatrics & Gerontology (226.3K) Gerontology (158.2K) Health Care Sciences & Services (433.8K) Hematology (653.3K) Immunology (896.7K) Infectious Diseases (453.2K) Medical Ethics (26.6K) Medical Informatics (100.5K) Medical Laboratory Technology (108K) Medicine, General & Internal (1.3M) Medicine, Legal (48.4K) Medicine, Research & Experimental (710K) Nursing (297.8K) Obstetrics & Gynecology (559.8K) Oncology (1.8M) Ophthalmology (452.2K) Orthopedics (359.5K) Otorhinolaryngology (166K) Pediatrics (655.3K) Peripheral Vascular Disease (595.7K) Pharmacology & Pharmacy (1.3M) Primary Health Care (59.2K) Psychiatry (755.1K) Radiology, Nuclear Medicine & Medical Imaging (799.4K) Rehabilitation (249.2K) Rheumatology (300.3K) Surgery (1.3M) Toxicology (333.1K) Transplantation (309.7K) Tropical Medicine (112.2K) Urology & Nephrology (567K) Veterinary Sciences (455.3K)

© Peeref 2019-2024. All rights reserved.