Instruments & Instrumentation

Article Chemistry, Analytical

ZnO quantum dots sensitized ZnSnO3 for highly formaldehyde sensing at a low temperature

Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang

Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Simultaneous detection of acetamiprid and carbendazim based on Raman-silent spectral window tags-mediated surface-enhanced Raman scattering aptasensor coupled with magnetic separation

Lixin Ma, Qian Xu, Limei Yin, Wei Wu, En Han, Chen Wang, Ruiyun Zhou, Junwen Bai, Jianrong Cai

Summary: In this study, simultaneous detection of acetamiprid and carbendazim in complex sample matrix was achieved using specific Raman tag molecules and aptamer-based nanoparticles. The method showed good resistance to spectral interference and easy separation, making it a promising approach for on-site detection of hazardous substances in food safety.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Electrochemical immunosensor for the quantification of galectin-3 in saliva

Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry

Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Optical hydrogen peroxide sensor for measurements in flow

Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr

Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

A biosensor using semi-DNA walker and CHA -FRET loop for ultrasensitive detection of single nucleotide polymorphism

Yunshan Zhang, Shijie Xu, Jian Chen, Lanyue Wang, Lina Bian, Jing Ye, Lin Weng, Xiaoyu Zhao, Cheng-Te Lin, Shuang Li, Diming Zhang

Summary: Single nucleotide polymorphisms (SNPs) are important biomarkers for disease diagnosis and prognosis. However, detecting SNPs with high specificity and sensitivity for DNA with single-base difference is challenging. This study proposes a strategy for ultrasensitive SNP detection using flap endonuclease 1 (FEN 1) manipulated semi-DNA walker reaction and catalytic hairpin assembly (CHA)-FRET loop. The strategy demonstrated superior performance for ultrasensitive detection of mutant KRAS gene and could be applied to monitor gene expression in cancer cells.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Towards cost-effective and lightweight surface plasmon resonance biosensing for H5N1 avian influenza virus detection: Integration of novel near-infrared organic photodetectors

Yu-Ching Huang, Sheng-Fan Wang, Bo-Cheng Chen, Zih-Syuan Yang, Meng-Chi Li, Xun-Ying Wu, Meng-Jey Youh, Hui-Yun Chou, Yu-Xen Lin, Wanchai Assavalapsakul, Arunee Thitithanyanont, Li-Chen Su

Summary: In this study, a intensity-based SPR sensor using NIR-OPD was introduced for rapid and accurate detection of H5N1 avian influenza virus. The sensor exhibited high sensitivity with a detection limit of 4.3 x 104 copies/mL, which was 37 times higher than a commercial lateral flow test kit. The integration of NIR-OPD into the sensor provided advantages in compactness and cost-effectiveness, making it a promising tool for on-site detection of H5N1 AIV.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Ultra-sensitive trace NO2 detection based on quantum dots-sensitized few-layer MXene: A novel convincing insight into dynamic gas-sensing mechanism

Guoqing Feng, Siqing Wang, Shihan Wang, Pengcheng Wang, Chuntao Wang, Yongxin Song, Jingkun Xiao, Chengwen Song

Summary: In this study, quantum dots (QDs)-sensitized few-layer Ti3C2Tx was successfully applied to NO2 sensing, showing a strong response, ideal selectivity, and a low detection limit. A novel dynamic gas-sensing mechanism was proposed to explain the enhancement of sensing performance by sensitization mechanisms. These findings not only demonstrate the potential of MXene in sensing applications, but also provide a theoretical perspective for designing trace-level NO2 sensors.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Highly sensitive and selective nanoengineered PtO2-BNNT heterostructures for ppb level ammonia gas sensing

Bharat Sharma, K. Karuppasamy, Ashok Kumar Srivastava, Akram Alfantazi, Ashutosh Sharma

Summary: In this study, boron nitride nanotubes (BNNTs) decorated PtO2 nanoparticles (NPs) were used to form a heterojunction for enhancing the room temperature gas sensing towards dry NH3 gas. The integration of PtO2 NPs onto BNNTs provides a synergistic effect, enabling enhanced NH3 sensing capabilities with low detection limit and short response time, as well as good resistance against humidity and long-term stability.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Development of V2O5@GO (1D/2D) nanohybrid based chemiresistor for low-trace of toluene

Shivangi Srivastava, Ajeet Singh, Mohammad A. Sahz, Bal Chandra Yadav, Narendra Kumar Pandey

Summary: A room temperature operated V2O5 nanorods-decorated graphene oxide (GO) nanosheets-nanocomposite chemiresistor has been developed for detecting low-trace of toluene. The sensor shows high response and rapid response and recovery time, as well as good selectivity and stability.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Simultaneous detection of multiplex biomarkers related with hepatocellular carcinoma by coupling DNase I-assisted recycling amplification and microfluidic electrokinetic stacking chip with parallel multi-channels

Runhui Zhang, Qing Tang, Hanren Chen, Jieqi Deng, Yongyin Li, Lihong Liu

Summary: In this study, a strategy for detecting hepatocellular cancer biomarkers was developed. This strategy involved the coupling of a 6-carboxyfluorescein labelled aptamer, reduced graphene oxide, DNase I-assisted recycling amplification, and microfluidic electrokinetic stacking chip. The method demonstrated high sensitivity and specificity in detecting multiple biomarkers simultaneously, and was successfully applied to clinical serum samples.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Concentric gradient nanoplasmonic sensors for detecting tumor-derived extracellular vesicles

Hongtao Feng, Siyi Min, Yuqing Huang, Zhuofei Gan, Chuwei Liang, Wen -Di Li, Yan Chen

Summary: This study presents a novel concentric gradient nanoplasmonic sensor for sensitive and label-free quantification of tumor-derived extracellular vesicles (EVs). By functionalizing the sensor with smaller aptamers, a more sensitive area is reserved for EV surface proteins, enabling the dynamic binding of EVs. The sensor exhibits high sensitivity in detecting EV binding and shows great potential for diagnosing cancer patients.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Quantitatively sensitive and resolution-enhancing strategies in optical signal conversion of SPR images using extensive angle-scanning and image-reconstruction

Yoonseung Lee, Youngbo Choi, Surin Hong

Summary: Surface plasmon resonance imaging (SPRi) is a widely-used technology in various fields, but it faces sensitivity limitations when handling low-molecular-mass materials. This study developed an SPRi signal conversion process to enhance image contrast and convert it into quantitatively analyzed signals.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Signal amplification strategy by chitosan-catechol hydrogel modified paper electrode for electrochemical detection of trace arsenite

Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi

Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Flexible enzyme-like platform based on a 1-D CeVO4/2-D rGO-MCC heterostructure as sensor for the detection of intracellular superoxide anions

Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan

Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Visualized time-temperature monitoring by triplet-sensitized ratiometric fluorescent nanosensors

Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song

Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

A fluorescent prodrug to fight drug-resistant lung cancer cells via autophagy-driven ferroptosis

Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian

Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Engineering, Mechanical

Study on the design of single-seat control valve with stable flow regulation and its fluid flow characteristics and thermal stress

Ruiming Yu, Yunyan Ma, Kuaile Liu, Xiangyu Liu

Summary: A single-seat control valve with stable flow regulation is researched and designed to address technical problems such as unstable flow at small openings and uneven force on the valve core. The mechanical and flow characteristics, as well as thermal stress, are analyzed through simulations and tests. The results show that the designed valve meets the requirements.

FLOW MEASUREMENT AND INSTRUMENTATION (2024)

Article Engineering, Mechanical

Experimental investigation of the hydraulic performance of porous bottom intakes

Mehdi Asadi, S. Abbas Hosseini, Kaveh Ahangari

Summary: Due to technical issues with bottom intake racks, porous intakes made of rock, gravel, or sand can be a viable alternative. This study used an experimental model to assess the performance of porous bottom intakes (PBI) and examined the impacts of various parameters such as channel slope, grain size distribution of the porous media, intake structure geometry, and water depth in the channel on diverted flow rates during sediment-free flow. The study also compared the performance of one-sided and three-sided PBI models under the same conditions. The findings suggest that a slope of 1% yields higher discharge coefficient and diverted flow compared to a slope of 1.68%, and three-sided PBI models outperform one-sided models in terms of flow rate. A formula utilizing nonlinear multivariate regression, experimental data, and dimensional analysis was proposed for calculating the discharge coefficient of PBI, with a high accuracy rate of over 95%.

FLOW MEASUREMENT AND INSTRUMENTATION (2024)

Article Instruments & Instrumentation

Vertical time-of-flight spectroscopy of ultracold neutrons

Thomas Neulinger, Hanno Filter, Oliver Zimmer

Summary: This paper describes the mathematical foundation for analyzing vertical time-of-flight (TOF) measurements using ultracold neutrons (UCN). It enables the spectroscopy of UCN with kinetic energies below the neutron optical potential of the detector entrance window. The paper provides general treatment methods and transformation rules for converting vertical TOF spectra into other spectra of interest.

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT (2024)

Article Engineering, Mechanical

A study of kinematic viscosity approach with air as a gas medium for turbine flowmeter calibration

Budi Rochmanto, Hari Setiapraja, Ihwan Haryono, Siti Yubaidah

Summary: This study calibrates a turbine flowmeter for compressed natural gas (CNG) application by using air as a substitute and simulating the kinematic viscosity property of CNG. The research shows that by using air instead of CNG, the flowmeter can achieve accurate measurements with a measurement uncertainty of less than 1%.

FLOW MEASUREMENT AND INSTRUMENTATION (2024)