Article
Chemistry, Analytical
Chun-Lin Lv, Chang Tang, Hongyan Zhou, Ai-Jun Wang, Jiu-Ju Feng, Tuck Yun Cheang
Summary: In this study, self-supported PtPdMnCoFe high-entropy alloy with nanochain-like internetworks was synthesized and found to be effective in reducing H2O2. It was used as a signal amplifier for the development of a novel label-free electrochemical amperometric immunosensor for ultrasensitive determination of biomarker NSE. The sensor showed a broad linear range and low detection limit for NSE immunoassay, and demonstrated satisfactory results in quantifying NSE in human serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Xiaoyan Lang, Xiaxia Xing, Xinhua Zhao, Lingling Du, Yingying Tian, Zhenxu Li, Xiaoyu Chen, Heliang Fan, Dachi Yang
Summary: This study developed NixCu3_x(HHTP)2/PPy nanocomposites for highly selective and stable H2S sensing at room temperature. The NixCu3_x(HHTP)2/PPy NCPs exhibited excellent selectivity to H2S and maintained a 77.3% response for 70 days at room temperature (- 25 degrees C). The sensor prototypes were able to detect H2S as low as 500 ppb and showed stability against humidity.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anran Gao, Fuwen Wang, Zishuo Fan, Shixing Chen, Kejin Wu
Summary: miRNAs have emerged as promising biomarkers in cancer research, but their detection remains challenging. In this study, a photo response calibration method was proposed to enhance the correlation between a silicon nanowire biosensor and q-PCR for the identification of breast cancer miRNA. The use of an uncharged peptide nucleic acid (PNA) for device modification improved the sensor's sensitivity in detecting low concentration miRNA. The improved biosensor demonstrated favorable selectivity and the ability to detect miRNA directly in authentic clinical samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Zhirui Li, Hui Huang, Danna Zhao, Shunji Chen, Weicheng Cai, Tianlin Tang
Summary: A reliable and high-performance oxygen sensor based on TiO2-decorated GaN nanowires was fabricated, which can operate under UV irradiation at room temperature. Experimental results showed that the sensor had maximum response and a limit of detection as low as 0.45% O2 when the TiO2 film thickness was 5 nm. In addition, the sensor exhibited enhanced O2 sensing with lower wavelength UV illumination. The sensor also demonstrated excellent repeatability, selectivity and long-term stability, making it suitable for various applications in the field of O2 gas sensing.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Pengying Liang, Mengxu Sun, Mengyu Chen, Tong Li, Ting Huang, Qingying Zhou, Chunrong Li, Baoping Xie, Jinxiang Chen, Zong Dai, Yuanxin Tian, Jun Chen
Summary: A novel feedback catalytic hairpin assembly (FCHA) was proposed for mRNA imaging in living cells, which demonstrated improved reaction kinetics and sensitivity compared to traditional CHA, and could be used for real-time imaging and indication of changes in mRNA expression.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ruili Wang, Lan Xu, Jishan Li
Summary: A novel visualized chemiluminescence sensor array was developed, which combines the cascade amplification of CHA and HCR with the catalytic activity of G-quadruplex DNAzyme, for simultaneous detection of four cancer-associated miRNAs.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Madhuka V. Liyanage, Robert A. Latour, George Chumanov
Summary: Nanocomposite films containing silver nanoparticles separated by thin polymer layers were fabricated using different methods. The films exhibited changes in electrical conductivity when exposed to moist ammonia and water vapors. The conductivity changes were attributed to hydrogen bonding and direct adsorption. Drop casting method on nylon filter membranes resulted in the most reproducible films. The films with polyvinylpyrrolidone polymer layers showed a low limit of detection for ammonia in the presence of interfering water vapor. The films could be developed as ammonia sensors for environmental and biomedical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Pengqi Gong, Xuegang Li, Qiming Zhao, Xue Zhou, Yanan Zhang, Yong Zhao
Summary: In this paper, a multiparameter DNA hybridization sensor with temperature and pH detection channels based on a fiber-based triple surface plasmon resonance (Triple-SPR) effect is demonstrated. The innovation of this paper lies in the independent temperature and pH testing channels implemented based on a single fiber optic structure, and the high sensitivity DNA hybridization detection channel. Polydimethylsiloxane and self-assembled materials are used for the real-time detection of temperature and pH. After the modification of probe DNA, the selective detection of complementary DNA is achieved. The advantages of multi-parameter independent detection, high sensitivity, and fast response of the fiber-based Triple-SPR sensing technology are of great significance in future multi-parameter sensing, compensated detection, and real-time bio-monitoring applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Kaiyue Han, Yang Li
Summary: In this study, a self-standing high performance flexible capacitive humidity sensor was developed using a composite of polyimide aerogel and graphene oxide. The sensor demonstrated high sensitivity and stability, and could monitor respiration and finger movement while also detecting water content in liquids.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weidong Qin, Junhua Wang, Zhanqiu Tang, Hongyuan Tian, Zhenglong Wu
Summary: Researchers have discovered a rapid and efficient method for immobilizing DNA on gold nanoclusters (AuNCs) using tris(2carboxyethyl)phosphine (TCEP). They have also successfully fabricated a core-shell-satellite nanocomposite for simultaneous detection of microRNA-21 and microRNA-141.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Zhang, Hong Lei, Jiachong Li, Xiaoyan Wang, Hui Yan
Summary: In this study, we proposed a dual signal enhancement strategy for the highly sensitive detection of microRNAs using a fiber optic localized surface plasmon resonance sensor. The method involved the construction of a multimer structure and catalytic amplification to capture and detect miR-103. The sensor demonstrated high specificity, repeatability, and reproducibility, and was successfully validated with real samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Chen Meng, Yunhai Chen, Dianwei Zhang, Huilin Liu, Baoguo Sun
Summary: In this study, a novel COFs(azide)@BAs material was prepared for the adsorption of urea and indirect control of EC in Huangjiu processing. The material exhibited a low detection limit for urea and satisfactory removal efficiency for EC, showing great potential for application in food safety control.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Naveen Kumar Arkoti, Kaushik Pal
Summary: Stable and selective gas sensing is crucial for detecting toxic gases and preventing gas leak accidents. In this study, borophene is identified as a potential material for NO2 gas sensing, while a polyetherimide-zeolitic imidazole framework mixed matrix membrane is used as a selective gas separation membrane. Experimental results demonstrate that the fabricated sensors exhibit stable and reliable detection performance for NO2 gas at varying concentrations.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Shuguo Yu, Chu Chen, Peng Li, Hongyan Zhang, Haiyang Zhang
Summary: A highly sensitive and stable Ti3C2Tx MXenes-RGO humidity sensor was developed for real-time respiratory monitoring. The sensor exhibits high sensitivity, low humidity hysteresis, short response/recovery time, and good stability and repeatability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Mengke Wang, Yaqing Han, Rui Huang, Zhonghao Wang, Guannan Wang
Summary: The confinement effect of AuNCs@HDS significantly improves the fluorescence properties of AuNCs and enables versatile fluorescent sensing strategy for bio-enzymes.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Junfeng Zhang, Kai Sun, Jiangtao Ren, Han Wang, Jing Cheng
Summary: A metallic nanowire aptasensor with high sensitivity and short detection time was developed for the early diagnosis and prognostic monitoring of heart failure by detecting cardiac troponin I (cTnI). The sensor exhibited excellent detection performance, including high sensitivity, short detection time, high specificity, and good reproducibility, making it a potential application in portable devices for continuous monitoring of cardiomyocyte injury.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jing-Yu Zhao, Gang Zhang, Hao-Chi Hao, Ru Sun, Yu-Jie Xu, Jian-Feng Ge
Summary: This study presents the discovery of mitochondria probes for real-time monitoring of mitophagy process. The probes showed excellent fluorescence performance and targeting capability, and were able to detect changes in mitochondrial viscosity. These probes have significant potential for investigating dynamic pathological processes related to mitophagy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Marc Clua Estivill, Adil Ait Yazza, Pascal Blondeau, Francisco J. Andrade
Summary: This study presents the development and optimization of a paper-based ion-selective organic electrochemical transistor (IS-OECT) with remarkable analytical performance. The device combines thick-film transistor technology, optimal ion-selective membrane composition and thickness to achieve high sensitivities and good selectivity for detecting potassium concentrations in blood.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Han Lu, Dan Wang, Guangfei Huang, Qilin Ma, Yuan Zhang, Mingliang Jin, Lingling Shui
Summary: Surface-enhanced Raman spectroscopy (SERS) has great potential in DNA analysis, but the identification of single-base mutations is still limited. In this work, plasmonic SiNW arrays decorated with Ag nanoparticles (SiNW@AgNP arrays) were developed to address these challenges, showing excellent sensitivity and reproducibility. Under optimized conditions, SiNW@AgNP arrays enable the detection of DNA bases and the discrimination of gene mutations.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Gianni Antonelli, Arianna Mencattini, Micol Massimiani, Valentina Lacconi, Joanna Filippi, Margherita Losardo, Michele 'Orazio, Paola Casti, Mario Bragaglia, Giorgia Curci, Francesca Nanni, Luisa Campagnolo, Eugenio Martinelli
Summary: Lab-On-Chips (LOCs) offer advantages in studying biological models and evaluating drug efficacy. This research presents a cost-effective technique to integrate optical biosensors into the lab-on-chip and successfully measures pH in human embryonic stem cell cultures, advancing the understanding of cell-scale metabolic mechanisms.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
