Health Care Sciences & Services

Article Health Care Sciences & Services

Evolving Trends and Economic Burden of Benzodiazepine Use: Insights From a 10-Year Predictive Model

Andro Koren, Luciana Koren, Robert Marcec, Darko Marcinko, Robert Likic

Summary: Benzodiazepines are widely prescribed in Croatia for various conditions, but long-term use is associated with negative side effects.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Cost-Utility Model of Nirmatrelvir/Ritonavir in Brazil: Analysis of a Vaccinated Population

Ricardo R. A. Fernandes, Bruno M. Barros, Milene R. da Costa, Carlos A. S. Magliano, Bernardo R. Tura, Quenia Cristina D. Morais, Marisa Santos

Summary: The use of nirmatrelvir/ritonavir in the treatment of COVID-19 in a vaccinated population was cost-effective only for immunosuppressed individuals and people over 60 years of age, while it showed a higher cost-effectiveness ratio for other groups.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Determining the Willingness to Pay for Innovative Oncology Medicines in Malaysia

Mohd Redhuan Dzulkipli, Asrul Akmal Shafie, Siti Noorsuriani Maon, Azuana Ramli, Abdul Haniff Mohammad Yahaya, See Wan Ho, Nor Ilham Ainaa Muhsin, Azmi Nor Mohd Farez Ahmat

Summary: This study aimed to determine the willingness to pay (WTP) for innovative oncology medicines among Malaysians. The results showed that more than half of the respondents were willing to pay for innovative oncology medicines, indicating the potential for collaborative funding mechanisms and appropriate financial screening to expedite access to these medicines in Malaysia.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

The Economic Burden of Biological Drugs in Rheumatoid Arthritis Treatment

Dominik Grega, Jozef Kolar

Summary: This study aimed to compare the direct (biological drugs only) and indirect (productivity loss) costs in patients with rheumatoid arthritis during the study period. The results showed that the indirect costs were 2.5 to 3 times lower than the costs of biological and targeted treatment.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Automated Peritoneal Dialysis With Remote Patient Monitoring: Clinical Effects and Economic Consequences for Poland

Joanna Augustynska, Monika Lichodziejewska-Niemierko, Beata Naumnik, Michal Seweryn, Agnieszka Leszczynska, Ryszard Gellert, Bengt Lindholm, Jacek Lange, Justyna Kopel

Summary: This study reviewed recent scientific research on the use of remote patient monitoring (RPM) in patients treated with automated peritoneal dialysis (APD), and assessed the clinical implications and potential economic value of introducing such a system into practice in Poland based on extracted relevant data. The results showed that APD with RPM significantly reduced hospitalization frequency and length, as well as APD technique failure and death.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Research-to-policy Partnerships for Evidence-Informed Resource Allocation in Health Systems in Africa: An Example Using the Thanzi Programme

Juliet Nabyonga-Orem, Edward Kataika, Alexandra Rollinger, Helen Weatherly

Summary: The Thanzi Programme is a research-and-policy partnership framework that supports evidence-informed health resource allocation decisions in Africa. It achieves this through providing health economics training, strengthening partnerships between in-country and international researchers, and institutionalizing platforms at national and regional levels. It also enhances the contribution of health economics evidence in policy processes through the establishment of Health Economics and Policy Units and the Health Economics Community of Practice.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Exploring the Evolution of Statin Pricing in Australia: Observations of Price Disclosure Effects on Pharmaceutical Benefits Scheme Expenditure

Leonard Lee, Hansoo Kim

Summary: This study investigates the impact of price control measures on statin prices and government expenditure in Australia. The results show that statin prices decreased under price control measures, leading to a reduction in government expenditure. The effects of price disclosure on market share suggest that industry-prompted price reductions may be driven by market share loss.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Experiences and perceptions of continuous deep sedation: An interview study among Dutch patients and relatives

Louise Annemoon Jonker, Madelon T. Heijltjes, Judith A. C. Rietjens, Agnes van der Heide, Geeske Hendriksen, Johannes J. M. van Delden, Ghislaine J. M. W. van Thiel

Summary: This study explores the perceptions and experiences of patients and relatives regarding Continuous Deep Sedation (CDS). The findings suggest that patients and relatives consider CDS as a regular palliative care option and prioritize avoiding suffering at the end of life. They also claim a substantial say in the decision-making process.

HEALTH EXPECTATIONS (2024)

Article Health Care Sciences & Services

Quality in screening and measuring blood pressure in China's primary health care: a national cross-sectional study using unannounced standardized patients

Lanping Zhang, Huijuan Liang, Huanyuan Luo, Wenjun He, Yiyuan Cai, Siyuan Liu, Yancun Fan, Wenxiu Huang, Qing Zhao, Dongmei Zhong, Jiaqi Li, Sensen Lv, Chunping Li, Yunyun Xie, Nan Zhang, Dong (Roman) Xu

Summary: This study evaluates the adherence of primary care providers in China to the standard of measuring blood pressure for people aged 35 or above during their initial visit, and identifies factors influencing their practices. The findings suggest that primary care hypertension screening in China falls short of guidelines, with infrequent blood pressure measurements and inadequate adherence to proper measurement steps.

LANCET REGIONAL HEALTH-WESTERN PACIFIC (2024)

Article Health Care Sciences & Services

The Chinese cardiorespiratory and circulatory system at work in women and men: a case-control study

Meihan Guo, Candela Diaz-Canestro, Ming-Yen Ng, Kai Hang Yiu, David Montero

Summary: This study compared the cardiorespiratory system between Hans Chinese and European-American individuals. It found that regardless of gender, Hans Chinese had higher body fat and lower lean body mass percentage than European-Americans. Additionally, in females, peak oxygen uptake and arteriovenous O2 difference were significantly reduced in Hans Chinese compared to European-Americans during high exercise intensity.

LANCET REGIONAL HEALTH-WESTERN PACIFIC (2024)

Article Health Care Sciences & Services

Comparison of control and transmission of COVID-19 across epidemic waves in Hong Kong: an observational study

Bingyi Yang, Yun Lin, Weijia Xiong, Chang Liu, Huizhi Gao, Faith Ho, Jiayi Zhou, Ru Zhang, Jessica Y. Wong, Justin K. Cheung, Eric H. Y. Lau, Tim K. Tsang, Jingyi Xiao, Irene O. L. Wong, Mario Martin-Sanchez, Gabriel M. Leung, Benjamin J. Cowling, Peng Wu

Summary: Strict non-pharmaceutical and pharmaceutical interventions in Hong Kong were effective in reducing transmission risks and interrupting local spread of COVID-19. However, the spread of the Omicron BA.2 variant could not be contained despite stringent measures. Increasing coverage of pharmaceutical interventions among high-risk groups reduced infection-related mortality and mitigated the adverse health impact of the pandemic.

LANCET REGIONAL HEALTH-WESTERN PACIFIC (2024)

Article Health Care Sciences & Services

Risk mapping and socio-ecological drivers of soil-transmitted helminth infections in the Philippines: a spatial modelling study

Tsheten Tsheten, Kefyalew Addis Alene, Angela Cadavid Restrepo, Matthew Kelly, Colleen Lau, Archie C. A. Clements, Darren J. Gray, Chona Daga, Vanessa Joy Mapalo, Fe Esperanza Espino, Kinley Wangdi

Summary: The study in the Philippines identified sociodemographic and environmental factors driving soil-transmitted helminth (STH) transmission, predicting high-risk areas in the country. Higher prevalence of Ascaris lumbricoides and Trichuris trichiura was found in Visayas Island, while hookworm prevalence was highest in Mindanao Island. Male gender, temperature, and rainfall were associated with increased STH risk, while normalized difference vegetation index and soil pH were negatively correlated with transmission. The identified high-risk areas can be targeted for deworming and health education activities to reduce the burden of STH infections.

LANCET REGIONAL HEALTH-WESTERN PACIFIC (2024)

Article Computer Science, Information Systems

Patients' perceptions, experiences, and satisfaction with e-prescribing system: A cross-sectional study

Jahanpour Alipour, Roxana Sharifian, Javid Dehghan Haghighi, Mehrnaz Hashemzehi, Afsaneh Karimi

Summary: This study investigated patients' perceptions of the e-prescribing system. The majority of patients were aware of e-prescribing, and preferred it over traditional prescriptions. Patients reported overall positive satisfaction and relatively positive perceptions and experiences with the e-prescribing system.

INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS (2024)

Article Computer Science, Information Systems

Longitudinal dynamic clinical phenotypes of in-hospital COVID-19 patients across three dominant virus variants in New York

Matthew Ho, Todd J. Levy, Ioannis Koulas, Kyriaki Founta, Kevin Coppa, Jamie S. Hirsch, Karina W. Davidson, Alex C. Spyropoulos, Theodoros P. Zanos

Summary: This study identified clinical phenotypes of hospitalized COVID-19 patients and investigated their longitudinal dynamics throughout the pandemic. Four distinct clinical phenotypes were associated with different mortality rates and showed variability across different viral variants. Factors such as sex, race/ethnicity, and treatment modalities revealed significant differences between the observed phenotypes. This methodology has the potential to guide evidence-based treatment strategies in a dynamic fashion.

INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS (2024)

Article Computer Science, Information Systems

A pediatric telecardiology system that facilitates integration between hospital-based services and community-based primary care

Savina Mannarino, Valeria Calcaterra, Giulia Fini, Andrea Foppiani, Antonio Sanzo, Martina Pisarra, Gabriele Infante, Marta Marsilio, Irene Raso, Sara Santacesaria, Gianvincenzo Zuccotti

Summary: This study introduces an innovative pediatric telecardiology system, seamlessly integrated with a hospital telemedicine platform, which enhances patient management in the community. The results demonstrate the system's value as a diagnostic tool to facilitate the execution, transmission, and reporting of ECG data between primary care pediatrician clinics and the hospital.

INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS (2024)

Article Economics

The labour market returns to sleep

Joan Costa-Font, Sarah Fleche, Ricardo Pagan

Summary: This study uses longitudinal data from Germany and finds that a one-hour increase in weekly sleep is associated with a rise in employment and an increase in weekly earnings. The effect on earnings comes from productivity improvements due to a decrease in working hours with longer sleep duration. The study also identifies improved mental well-being as a key mechanism driving these effects.

JOURNAL OF HEALTH ECONOMICS (2024)

Article Health Care Sciences & Services

Decision-Utility Analysis of Empiric Treatment Versus Test and Treat Strategies for Helicobacter pylori in Patients With Duodenal Ulcer

Majid Alsaha Fi, Mahmoud Mosli, Saad Alkhowaiter, Fergal Donnellan

Summary: This study compares the utility and ulcer recurrence rate of empiric treatment strategy and test and treat strategy in patients with uncomplicated duodenal ulcer. The results show that the empiric treatment strategy, within a specific range of test sensitivity, can lower the recurrence rate and result in higher quality-adjusted life-year (QALY) compared to the test and treat strategy.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Review Computer Science, Information Systems

Interdisciplinary collaboration in critical care alarm research: A bibliometric analysis

Louis Agha-Mir-Salim, Lucas McCullum, Enrico Dahnert, Yanick-Daniel Scheel, Ainsley Wilson, Marianne Carpio, Carmen Chan, Claudia Lo, Lindsay Maher, Corinna Dressler, Felix Balzer, Leo Anthony Celi, Akira-Sebastian Poncette, Michele M. Pelter

Summary: Alarm fatigue is a significant issue in the intensive care unit, and collaboration between nurses and engineers is crucial for finding solutions. However, the current research lacks sufficient involvement of nurses, leading to a lack of successful real-world solutions.

INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS (2024)

Review Health Care Sciences & Services

Heat impacts on human health in the Western Pacific Region: an umbrella review

Y. T. Eunice Lo, Emily Vosper, Julian P. T. Higgins, Guy Howard

Summary: High temperatures and heatwaves are becoming more frequent in the Western Pacific Region due to climate change. There is currently a lack of comprehensive evidence on the health impacts of heat in this region, highlighting the need for further research.

LANCET REGIONAL HEALTH-WESTERN PACIFIC (2024)

Article Health Care Sciences & Services

The Checklist for Standard Methodological Requirements and Reporting of Economic Evaluation of Medicines in Slovakia

Maria Bucek Psenkova, Lucia Hlavinkova, Martin Visnansky, Dominik Grega, Martina Ondrusova

Summary: This study developed a scientifically grounded checklist for economic evaluation (EE) of medicines in the Slovak health technology assessment process. The checklist was validated through an online survey and consists of 55 recommendations. Implementation of the checklist can help improve the appropriateness and standardization of EE in Slovakia.

VALUE IN HEALTH REGIONAL ISSUES (2024)