Gerontology

Article Geriatrics & Gerontology

Low Dose Lithium Treatment of Behavioral Complications in Alzheimer's Disease: Lit-AD Randomized Clinical Trial

D. P. Devanand, Elizabeth Crocco, Brent P. Forester, Mustafa M. Husain, Seonjoo Lee, Ipsit V. Vahia, Howard Andrews, Laura Simon-Pearson, Nadia Imran, Luminita Luca, Edward D. Huey, Deborah A. Deliyannides, Gregory H. Pelton

Summary: Low-dose lithium treatment for agitation in AD patients did not show significant efficacy, but was associated with overall clinical improvement and safety. In some aspects, lithium had better efficacy compared to placebo. Larger trials may be needed to evaluate lithium's response for patients with overlapping symptoms of mania.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2022)

Article Psychology, Clinical

Close social relationships and loneliness: the role of subjective age

Naama Spitzer, Dikla Segel-Karpas, Yuval Palgi

Summary: This study aims to evaluate the association between close social relationships and loneliness, as well as the moderating role of subjective age in this association. The results showed a negative relationship between the number of close social relationships and loneliness. Furthermore, the study found that subjective age moderates the relationship, with those having an older subjective age experiencing a weaker association between close social relationships and loneliness. Efforts to address loneliness in older adults should take into account their perceptions of aging.

INTERNATIONAL PSYCHOGERIATRICS (2022)

Article Geriatrics & Gerontology

Pre-pandemic Ageism Toward Older Adults Predicts Behavioral Intentions During the COVID-19 Pandemic

Ashley Lytle, MaryBeth Apriceno, Jamie Macdonald, Caitlin Monahan, Sheri R. Levy

Summary: This study found a relationship between ageism among undergraduates and their intentions to help older adults during the COVID-19 pandemic. The results highlight the complexity of predicting helping behaviors and suggest that even supportive behaviors may be influenced by ageist stereotypes during a crisis.

JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES (2022)

Article Gerontology

Socioeconomic differences in informal caregiving in Europe

Nekehia T. Quashie, Melanie Wagner, Ellen Verbakel, Christian Deindl

Summary: This study reveals that individuals with lower socioeconomic resources are more likely to provide informal care to older adults within the household. At the macro-level, income inequality and social spending are associated with the likelihood of older adults receiving care within the household.

EUROPEAN JOURNAL OF AGEING (2022)

Article Gerontology

Exploring Factors Enhancing Resilience Among Marginalized Older Adults During the COVID-19 Pandemic

Kathy Lee, Kate Hyun, Jaci Mitchell, Troyee Saha, Nilufer Oran Gibson, Caroline Krejci

Summary: Marginalized older adults have shown resilience in the face of COVID-19 by utilizing individual, community, and societal resources. Despite the impact on their physical and mental health, they have overcome adversity by using technology, accessing support from their community and family, and staying physically active.

JOURNAL OF APPLIED GERONTOLOGY (2022)

Article Geriatrics & Gerontology

Low Serum Klotho Associated With All-cause Mortality Among a Nationally Representative Sample of American Adults

Jacob K. Kresovich, Catherine M. Bulka

Summary: In this study, it was found that low serum klotho concentrations were associated with a 31% higher risk of mortality, particularly in relation to heart disease or cancer. Additionally, low serum klotho levels were more strongly linked to mortality among individuals who did not meet physical activity guidelines.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2022)

Article Geriatrics & Gerontology

Associations of social isolation, social participation, and loneliness with frailty in older adults in Singapore: a panel data analysis

Lixia Ge, Chun Wei Yap, Bee Hoon Heng

Summary: This study found that increased social participation was associated with lower frailty levels, while feelings of loneliness were associated with higher frailty levels. Social isolation was not associated with frailty. Gender did not moderate these associations.

BMC GERIATRICS (2022)

Article Gerontology

Perceptions and expectations of filial piety among older Chinese immigrants in Canada

Weiguo Zhang

Summary: This study investigates the specific perceptions of filial piety and parental expectations of filial duty among older Chinese immigrants in Canada. The findings show that while the perceptions of filial piety varied, almost all participants had reduced expectations of their children. However, they still valued and expected emotional care from their children. The study suggests that changes in institutional settings, social policies, and welfare systems in the host society define parents' support needs and affect their expectations, while norms and institutional settings in the place of origin influence their perceptions of filial piety.

AGEING & SOCIETY (2022)

Review Geriatrics & Gerontology

Prevalence and factors associated with polypharmacy: a systematic review and Meta-analysis

Mahin Delara, Lauren Murray, Behnaz Jafari, Anees Bahji, Zahra Goodarzi, Julia Kirkham, Zia Chowdhury, Dallas P. Seitz

Summary: This systematic review and meta-analysis estimated the pooled prevalence of polypharmacy and factors associated with polypharmacy. The results showed that polypharmacy is common, especially among older adults and inpatient populations. Clinicians should be aware of the prevalence of polypharmacy and make efforts to minimize inappropriate polypharmacy.

BMC GERIATRICS (2022)

Review Gerontology

Enhancing Older Adults' Well-Being and Quality of Life Through Purposeful Activity: A Systematic Review of Intervention Studies

Rebecca Owen, Katherine Berry, Laura J. E. Brown

Summary: Based on the research findings, purposeful activity interventions for older adults aged 80 years and older, particularly those involving functional roles, can improve their sense of well-being and quality of life. These results have implications for professionals and caregivers to help older adults access more meaningful social roles.

GERONTOLOGIST (2022)

Article Geriatrics & Gerontology

Identification of Dementia in Recent Medicare Claims Data, Compared With Rigorous Clinical Assessments

Francine Grodstein, Chiang-Hua Chang, Ana W. Capuano, Melinda C. Power, David X. Marquez, Lisa L. Barnes, David A. Bennett, Bryan D. James, Julie P. W. Bynum

Summary: Recent Medicare claims perform reasonably well in identifying dementia, but there are some differences compared to rigorous cohort evaluations.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2022)

Article Geriatrics & Gerontology

Proteome-Wide Analysis Using SOMAscan Identifies and Validates Chitinase-3-Like Protein 1 as a Risk and Disease Marker of Delirium Among Older Adults Undergoing Major Elective Surgery

Sarinnapha M. Vasunilashorn, Simon T. Dillon, Noel Y. Chan, Tamara G. Fong, Marie Joseph, Bridget Tripp, Zhongcong Xie, Long H. Ngo, Chun Geun Lee, Jack A. Elias, Hasan H. Otu, Sharon K. Inouye, Edward R. Marcantonio, Towia A. Libermann

Summary: This study identified CHI3L1/YKL-40 protein as associated with postoperative delirium, with high levels of CHI3L1/YKL-40 preoperatively and IL6 postoperatively increasing the risk of delirium.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2022)

Article Gerontology

Re-thinking and re-positioning 'being in the moment' within a continuum of moments: introducing a new conceptual framework for dementia studies

John David Keady, Sarah Campbell, Andrew Clark, Robyn Dowlen, Ruth Elvish, Lesley Jones, Jackie Kindell, Caroline Swarbrick, Sion Williams

Summary: This article draws on six social research studies completed by the Dementia and Ageing Research Team at The University of Manchester to construct a continuum of moments in the lived experience of dementia, comprising creating, being, ending, and reliving the moment.

AGEING & SOCIETY (2022)

Article Geriatrics & Gerontology

Perceptions, feelings, and the routine of older adults during the isolation period caused by the COVID-19 pandemic: a qualitative study in four countries

Amanda Ribeiro Goncalves, Joyce Lorena Maia Barcelos, Ana Paula Duarte, Giancarlo Lucchetti, Deborah Ribeiro Goncalves, Fabiana Caetano Martins Dutra, Jurema Ribeiro Luiz Goncalves

Summary: The qualitative study evaluated the knowledge, routine, and perception of older adults from four countries about dealing with COVID-19 during social isolation. The findings showed that older persons felt restricted in daily life activities, experienced emotional instability, but demonstrated similar adaptation abilities, coping strategies, and improved understanding of the disease based on media information. The homogeneity in their responses indicated that the pandemic affected them in a similar way, despite living in different cultures and contexts.

AGING & MENTAL HEALTH (2022)

Article Geriatrics & Gerontology

Navigating the new normal: accessing community and institutionalised care for dementia during COVID-19

Clarissa Giebel, Kerry Hanna, Steve Callaghan, Jacqui Cannon, Sarah Butchard, Justine Shenton, Aravind Komuravelli, Stan Limbert, Hilary Tetlow, Carol Rogers, Ruth Eley, Manoj Rajagopal, Kym Ward, Mark Gabbay

Summary: This study found that during the COVID-19 pandemic, many care services have not effectively adapted to provide remote support, leading to difficulties in access and severe physical and cognitive deterioration for people living with dementia and their carers. While remote support can be helpful, it cannot replace the benefits of face-to-face support.

AGING & MENTAL HEALTH (2022)

Article Gerontology

Understanding Aging in Place: Home and Community Features, Perceived Age-Friendliness of Community, and Intention Toward Aging in Place

Yeon Jin Choi

Summary: The study found that the availability of age-friendly features has a positive impact on the perceived age-friendliness of a community and the intention to age in place, influencing older adults' perception and desire for aging in place. Housing, outdoor spaces and buildings, and transportation domains are identified as crucial features in promoting age-friendliness of community and supporting aging in place. Policymakers and practitioners may need to prioritize promoting an age-friendly built environment before focusing on the social environment to build age-friendly communities.

GERONTOLOGIST (2022)

Article Geriatrics & Gerontology

Cumulative effect of loneliness and social isolation on health outcomes among older adults

Timothy L. Barnes, Stephanie MacLeod, Rifky Tkatch, Manik Ahuja, Laurie Albright, James A. Schaeffer, Charlotte S. Yeh

Summary: This study investigates the cumulative effects of loneliness and social isolation on late-life health outcomes, finding that older adults who are both lonely and socially isolated are more likely to have higher medical costs and emergency room visit rates. The results emphasize the importance of taking measures targeting older adults who are both lonely and socially isolated.

AGING & MENTAL HEALTH (2022)

Article Geriatrics & Gerontology

Volunteering and loneliness in older adults: A parallel mediation model

Sunwoo Lee

Summary: The study found that two forms of volunteer works, namely, volunteer youth work and charity work, significantly predicted perceived control, social self-efficacy, and lower levels of loneliness. Perceived control and social self-efficacy appeared to significantly mediate the relationship between volunteer activities and loneliness.

AGING & MENTAL HEALTH (2022)

Article Geriatrics & Gerontology

Testing the Effects of a Multicomponent Frailty Management Program for Community-Dwelling Older Adults in Singapore: A Feasibility Study

Tianma Xu, Ting-Ting Yeh, Kidman Yi Jer Ng, Nicole Wen Ru Wong, Verna Sock Juen Koh

Summary: This study aimed to determine the feasibility and effects of a multicomponent frailty management program (mFMP) in reducing frailty and increasing participation among frail community-living older adults. The results showed that the mFMP demonstrated its feasibility and exhibited a trend to facilitate personal behavioral changes postintervention.

JOURNAL OF AGING AND PHYSICAL ACTIVITY (2023)

Editorial Material Gerontology

Social, health and economic impact of the COVID-19 pandemic from a European perspective

Thorsten Kneip, Axel Boersch-Supan, Karen Andersen-Ranberg

EUROPEAN JOURNAL OF AGEING (2022)