Geriatrics & Gerontology

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Article Geriatrics & Gerontology

Demographic transition and hospital admissions in Spanish centenarians, 2004-2020: Geographical variations and sex-related differences

Juan Carlos Pineiro-Fernandez, Ramon Rabunal-Rey, Ana Maseda, Eva Romay-Lema, Roi Suarez-Gil, Sonia Pertega-Diaz

Summary: This study describes the distribution and temporal trends of the centenarian population and their hospital admissions in Spain over the past two decades. It found a significant increase in the centenarian population and hospital admissions, with regional and sex-based differences. Women represented a larger proportion of centenarians and hospital admissions. Understanding these trends and differences is crucial for implementing interventions that ensure adequate healthcare for centenarians.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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Letter Geriatrics & Gerontology

Comment on Cognitive impairment and risks of osteoporosis: A systematic review and meta-analysis

Chengxin Xie, Hua Luo

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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Article Geriatrics & Gerontology

Dispensing of antineoplastic medications and their impact on the dispensing of anti-dementia drugs for adults aged ≥60 years: A cohort study

Osvaldo P. Almeida, Christopher Etherton-Beer, Frank Sanfilippo, David B. Preen, Amy Page

Summary: The use of antineoplastic medications has been found to be associated with a decreased risk of dementia, which may contribute to the development of novel approaches for dementia prevention.

MATURITAS (2024)

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Article Geriatrics & Gerontology

Cutaneous Fungal Infections in Older Adults

Saniya Shaikh, Aditya Nellore

Summary: As the patient population aged older than 65 years increases, it becomes crucial to recognize and treat skin conditions seen in this age group. Treatment choices should take into consideration the physiological characteristics of older adults, their long medication lists, and their social living conditions. Simple regimens with low risk of drug interactions should be prescribed to these patients to enhance their quality of life.

CLINICS IN GERIATRIC MEDICINE (2024)

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Article Geriatrics & Gerontology

Swimming alters some proteins of skeletal muscle tissue in rats with Alzheimer-like phenotype

Mohammad Soleimani Farsani, Mohammad Fathi, Zahra Hemati Farsani, Zinab Gourgin Karaji

Summary: Swimming training has a significant effect on the expression of Neural cell adhesion molecule (NCAM), Semaphorin 3A (SEMA3A), and Profilin-1 (PFN1) proteins in the gastrocnemius muscle of Alzheimer-like phenotype rats.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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Article Geriatrics & Gerontology

Development and implementation of multicomponent homecare interventions for multimorbid and frail older people based on Information and Communication Technologies: The MULTIPLAT_AGE project

Alberto Pilotto, Marina Barbagelata, Wanda Morganti, Emanuele Seminerio, Guido Iaccarino, Armando Genazzani, Carlo Trompetto, Gennarina Arabia, Maddalena Illario, Erica Volta, Carlo Custodero, Alberto Cella

Summary: The prevention and treatment of frailty condition among multimorbid older adults is becoming a healthcare priority. A multidimensional approach using information and communication technology (ICT) offers a way to implement and monitor personalized interventions. The MULTIPLAT_AGE project aims to provide multidimensional interventions for older adults using a shared online platform, including transitional care, automatic home-care, appropriate drug prescription, tele-rehabilitation, and remote cognitive stimulation.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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Article Geriatrics & Gerontology

Associations of individual chronic diseases and multimorbidity with multidimensional frailty

Robbert J. J. Gobbens, Sandra Kuiper, Henriette Dijkshoornf, Marcel A. L. M. van Assen

Summary: This study examined the associations between chronic diseases and multidimensional frailty comprising physical, psychological, and social frailty. The results showed that chronic diseases, especially urinary incontinence and severe back disorder, were associated with frailty. The study recommends assigning different weights to individual chronic diseases in measuring multimorbidity and its effects on multidimensional frailty.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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Article Geriatrics & Gerontology

Bidirectional associations of high-level cognitive domains with hand motor function and gait speed in high-functioning older adults: A 7-year study

Kimi Estela Kobayashi-Cuya, Ryota Sakurai, Naoko Sakuma, Hiroyuki Suzuki, Susumu Ogawa, Toru Takebayashi, Yoshinori Fujiwara

Summary: The study found a positive bidirectional association between hand dexterity and maximum gait speed with executive function performance, while handgrip strength and usual gait speed showed no associations. This suggests that hand dexterity and motor speed have an important impact on cognitive function and are mutually dependent on each other.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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Article Geriatrics & Gerontology

Utility of iron biomarkers in differentiating menopausal status: Findings from CoLaus and PREVEND

Lum Kastrati, Dion Groothof, Hugo G. Quezada-Pinedo, Hamidreza Raeisi-Dehkordi, Lia Bally, Martin H. De Borst, Stephan J. L. Bakker, Pedro-Marques Vidal, Michele F. Eisenga, Taulant Muka

Summary: The study aimed to examine the association between iron biomarkers and menopausal status and assess whether these biomarkers can help differentiate menopausal status beyond age. The results showed that iron biomarkers were significantly associated with menopausal status in both cohorts and modestly improved a model with age alone for differentiating menopause status.

MATURITAS (2024)

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Article Geriatrics & Gerontology

Social isolation and risk of disability in older adults: Effect modification of metabolic syndrome

Masanori Morikawa, Sangyoon Lee, Keitaro Makino, Kenji Harada, Osamu Katayama, Kouki Tomida, Ryo Yamaguchi, Chiharu Nishijima, Kazuya Fujii, Yuka Misu, Hiroyuki Shimada

Summary: This study investigates the interaction effect of social isolation (SI) and metabolic syndrome (MetS) on disability onset in older adults. The results show that the co-occurrence of SI and MetS increases the risk of disability onset in older adults.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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Article Geriatrics & Gerontology

Association between changes in potentially inappropriate medication use and adverse outcomes during hospitalization in older adults: A retrospective study

Ying-Hsin Hsu, Ming-Yueh Chou, Wei-Cheng Chang, Miao-Ting Chen, Yu-Chun Wang, Mei-Chen Liao, Chih-Kuang Liang, Liang-Kung Chen, Yu-Te Lin

Summary: This study evaluated the association between the change in the number of potentially inappropriate medications (PIMs) in older adults during hospitalization and adverse outcomes. The results showed that increasing PIM use was strongly associated with higher functional decline, prolonged length of stay, and mortality rate. Older adults with three or more PIMs had the greatest risk for adverse outcomes during hospitalization.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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Article Geriatrics & Gerontology

Sleep disturbances and interrelationship between persons with dementia and family caregivers: The lived experiences of Korean American Dyads

Eunae Ju, Candace Burton, Julie Kim, Yuqing Guo, Jung In Park, Annie Qu, Lisa Gibbs, Jung-Ah Lee

Summary: This study investigates the sleep quality in dyadic interrelationships between Korean American persons with dementia (PWD) and their family caregivers. The findings reveal bidirectional influences in the sleep disturbances of these dyads, where caregiving impacts PWD sleep as part of an interactional unit. Communication barriers and limited community resources pose challenges for these dyads, highlighting the importance of culturally competent interventions.

GERIATRIC NURSING (2024)

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Article Geriatrics & Gerontology

Revealing the divide: Contrasting COVID-19 outcomes in Green Houses and traditional nursing homes in the United States

Yuchi Young, Wan-Hsiang Hsu, Ashley Shayya, Virgile Barnes, Taylor Perre, Thomas O. ' Grady

Summary: This study compares the case and mortality rates of COVID-19 in Green Houses (GHs) and traditional nursing homes (NHs) during the pandemic. The study found that, after adjusting for age, gender, and ADL disability, GHs demonstrated lower COVID-19 case and mortality rates than traditional NHs.

GERIATRIC NURSING (2024)

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Article Oncology

Longitudinal changes in cognitive and physical function and health-related quality of life in older adults with acute myeloid leukemia

Vijaya R. Bhatt, Christopher Wichman, Thuy T. Koll, Alfred L. Fisher, Tanya M. Wildes, Ann Berger, James O. Armitage, Sarah A. Holstein, Lori J. Maness, Krishna Gundabolu

Summary: A study on older adults with AML receiving chemotherapy showed significant comorbidity burden and functional impairments at baseline, but cognitive and physical function improvements or stability, as well as improved depression scores, were observed in a high proportion of patients at three months post-treatment, indicating success of treatment.

JOURNAL OF GERIATRIC ONCOLOGY (2024)

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Review Geriatrics & Gerontology

The influence of environmental factors on premature ovarian insufficiency and ovarian aging

Nikolaos Evangelinakis, Eleni V. Geladari, Charalampia V. Geladari, Adamantia Kontogeorgi, Georgios-Konstantinos Papaioannou, Melpomeni Peppa, Sophia Kalantaridou

Summary: Premature ovarian insufficiency and ovarian aging are complex conditions that affect women's reproductive health and overall well-being. This review explores the influence of environmental factors, including endocrine-disrupting chemicals and lifestyle choices, on the development and progression of these conditions. Understanding the impact of environmental factors is important for public and clinical health contexts.

MATURITAS (2024)

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Article Geriatrics & Gerontology

Rural racial disparities and barriers in mammography utilization among Medicare beneficiaries in Texas: A longitudinal study

Zhaoli Liu, Yong Shan, Yong-Fang Kuo, Sharon H. Giordano

Summary: This study examined racial/ethnic disparities in mammography screening practices among rural Medicare beneficiaries. The study found that rural Hispanics and non-Hispanic Blacks had lower rates of regular mammography use compared to their urban counterparts. Barriers to routine mammography screening included a lack of primary care provider, frequent hospitalization, and comorbidity.

GERIATRIC NURSING (2024)

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Article Oncology

Risk of dementia among older patients with lymphoma: A Danish nationwide matched cohort study

Eva Futtrup Maksten, Lasse Hjort Jakobsen, Boris Modrau, Hilde Jensvoll, Kristian Hay Kragholm, Judit Meszaros Jorgensen, Michael Roost Clausen, Robert Schou Pedersen, Andriette Dessau-Arp, Thomas Stauffer Larsen, Christian Bjorn Poulsen, Anne Ortved Gang, Peter Brown, Tarec C. El-Galaly, Marianne Tang Severinsen

Summary: The risk of developing dementia is not increased after lymphoma treatment among patients.

JOURNAL OF GERIATRIC ONCOLOGY (2024)

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Review Oncology

Self-reported electronic symptom monitoring in older patients with multimorbidity treated for cancer: Development of a core dataset based on expert consensus, literature review, and quality of life questionnaires

P. A. L. Nelleke Seghers, Marije E. Hamaker, Shane O'Hanlon, Johanneke E. A. Portielje, Hans Wildiers, Pierre Soubeyran, Annemarie Coolbrandt, Siri Rostoft

Summary: This study identified a core set of symptoms to monitor in older patients with multimorbidity treated for cancer. These symptoms include those related to cancer, treatment side effects, functional decline, and destabilization of comorbidities. The results provide a basis for guiding symptom monitoring during cancer treatment.

JOURNAL OF GERIATRIC ONCOLOGY (2024)

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Article Geriatrics & Gerontology

Predictors of self-regulation fatigue patterns in patients before total knee arthroplasty: A cross-sectional study

Yawei Shan, Haiying Lu, Xiaoyu Liu, Ru Chen, Jing Shang

Summary: This study aimed to identify subgroups of patients before total knee arthroplasty based on the heterogeneous patterns of self-regulation fatigue and analyze the predictors of these subtypes. The results revealed three latent classes: low, medium, and high self-regulation fatigue. Lower levels of hope, social support, self-efficacy, and education were identified as major predictors for the high self-regulation fatigue class. These predictors can help identify vulnerable populations and provide a foundation for targeted interventions.

GERIATRIC NURSING (2024)

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Article Geriatrics & Gerontology

Circadian rest-activity rhythms and cognitive decline and impairment in older Chinese adults: A multicohort study with prospective follow-up

Zhihui Lu, Jason C. S. Leung, Hongliang Feng, Jihui Zhang, Yun Kwok Wing, Timothy C. Y. Kwok

Summary: This study aimed to investigate the association between rest-activity rhythms and cognitive health in older adults. The findings suggest that lower relative amplitude of rest-activity rhythms may serve as a reliable biomarker for cognitive decline and impairment.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2024)

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