Endocrinology & Metabolism

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Article Endocrinology & Metabolism

IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045

Hong Sun, Pouya Saeedi, Suvi Karuranga, Moritz Pinkepank, Katherine Ogurtsova, Bruce B. Duncan, Caroline Stein, Abdul Basit, Juliana C. N. Chan, Jean Claude Mbanya, Meda E. Pavkov, Ambady Ramachandaran, Sarah H. Wild, Steven James, William H. H. Herman, Ping Zhang, Christian Bommer, Shihchen Kuo, Edward J. J. Boyko, Dianna J. Magliano

Summary: This study provides global, regional, and country-level estimates of diabetes prevalence and health expenditures for 2021 and projections for 2045. The global prevalence of diabetes is increasing and is expected to have the greatest relative increase in middle-income countries. Diabetes-related health expenditures are also projected to rise.

DIABETES RESEARCH AND CLINICAL PRACTICE (2022)

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Article Endocrinology & Metabolism

2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2022

Summary: The American Diabetes Association's Standards of Medical Care in Diabetes provide clinical practice recommendations, treatment goals, and tools for evaluating the quality of care in diabetes management.

DIABETES CARE (2022)

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Article Endocrinology & Metabolism

9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2022

Summary: The American Diabetes Association's Standards of Medical Care in Diabetes provides clinical practice recommendations and tools to evaluate quality of care. It is updated regularly by a committee of experts.

DIABETES CARE (2022)

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Article Endocrinology & Metabolism

Overview of the 2022 WHO Classification of Thyroid Neoplasms

Zubair W. Baloch, Sylvia L. Asa, Justine A. Barletta, Ronald A. Ghossein, C. Christofer Juhlin, Chan Kwon Jung, Virginia A. LiVolsi, Mauro G. Papotti, Manuel Sobrinho-Simoes, Giovanni Tallini, Ozgur Mete

Summary: This review summarizes the changes in the 5th edition of the WHO Classification of Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new classification provides a more detailed understanding of the different types of thyroid tumors based on their cell of origin, pathologic features, molecular profiles, and biological behavior. It also introduces new categories, such as thyroid follicular nodular disease, non-invasive follicular thyroid neoplasm with papillary-like nuclear features, and high-grade differentiated thyroid carcinomas. The classification emphasizes the importance of biomarkers in diagnosis and prognosis.

ENDOCRINE PATHOLOGY (2022)

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Article Endocrinology & Metabolism

Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Melanie J. Davies, Vanita R. Aroda, Billy S. Collins, Robert A. Gabbay, Jennifer Green, Nisa M. Maruthur, Sylvia E. Rosas, Stefano Del Prato, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Tsvetalina Tankova, Apostolos Tsapas, John B. Buse

Summary: The American Diabetes Association and the European Association for the Study of Diabetes have updated the consensus statements on the management of hyperglycemia in adults with type 2 diabetes. The new recommendations highlight the importance of social determinants of health, weight management, and provide practical tips for implementation.

DIABETES CARE (2022)

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Review Cell Biology

The hallmarks of cancer metabolism: Still emerging

Natalya N. Pavlova, Jiajun Zhu, Craig B. Thompson

Summary: The metabolism of cancer cells is highly adaptable, allowing them to sustain growth and proliferation. This adaptation can also influence the behavior of non-transformed cells in the tumor vicinity.

CELL METABOLISM (2022)

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Article Endocrinology & Metabolism

10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes-2022

Summary: The American Diabetes Association provides clinical practice recommendations and evaluation tools through the Diabetes Standards of Medical Care. The standards are updated annually or more frequently by a multidisciplinary committee.

DIABETES CARE (2022)

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Review Endocrinology & Metabolism

Exerkines in health, resilience and disease

Lisa S. Chow, Robert E. Gerszten, Joan M. Taylor, Bente K. Pedersen, Henriette van Praag, Scott Trappe, Mark A. Febbraio, Zorina S. Galis, Yunling Goo, Jacob M. Haus, Ian R. Lanza, Carl J. Lavie, Chih-Hao Lee, Alejandro Lucia, Cedric Moro, Ambarish Pandey, Jeremy M. Robbins, Kristin Stanford, Alice E. Thackray, Saul Villeda, Matthew J. Watt, Ashley Xia, Juleen R. Zierath, Bret H. Goodpaster, Michael P. Snyder

Summary: This Review summarizes the importance and current state of exerkine research, highlighting the potential roles of exerkines in improving cardiovascular, metabolic, immune, and neurological health. Exerkines are signaling molecules released during exercise, which have the potential for the treatment of cardiovascular disease, type 2 diabetes mellitus, obesity, and to facilitate healthy aging.

NATURE REVIEWS ENDOCRINOLOGY (2022)

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Article Endocrinology & Metabolism

Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Melanie J. Davies, Vanita R. Aroda, Billy S. Collins, Robert A. Gabbay, Jennifer Green, Nisa M. Maruthur, Sylvia E. Rosas, Stefano Del Prato, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Tsvetalina Tankova, Apostolos Tsapas, John B. Buse

Summary: The American Diabetes Association and the European Association for the Study of Diabetes have updated the consensus statements on the management of hyperglycaemia in type 2 diabetes in adults. The new recommendations focus on social determinants of health, physical activity behaviors, and weight management.

DIABETOLOGIA (2022)

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Article Endocrinology & Metabolism

6. Glycemic Targets: Standards of Medical Care in Diabetes-2022

Summary: The American Diabetes Association provides clinical practice recommendations and tools for evaluating diabetes care quality through their medical care standards. The standards are updated annually and comments are welcome on their professional website.

DIABETES CARE (2022)

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Article Endocrinology & Metabolism

Risks and burdens of incident diabetes in long COVID: a cohort study

Yan Xie, Ziyad Al-Aly

Summary: This study found an increased risk and burden of incident diabetes and antihyperglycaemic use in people with COVID-19 in the post-acute phase compared to a contemporary control group. The risks and burdens of post-acute outcomes were related to the severity of the acute phase of COVID-19.

LANCET DIABETES & ENDOCRINOLOGY (2022)

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Article Endocrinology & Metabolism

Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo

Michael P. Murphy, Hulya Bayir, Vsevolod Belousov, Christopher J. Chang, Kelvin J. A. Davies, Michael J. Davies, Tobias P. Dick, Toren Finkel, Henry J. Forman, Yvonne Janssen-Heininger, David Gems, Valerian E. Kagan, Balaraman Kalyanaraman, Nils-Goran Larsson, Ginger L. Milne, Thomas Nystrom, Henrik E. Poulsen, Rafael Radi, Holly Van Remmen, Paul T. Schumacker, Paul J. Thornalley, Shinya Toyokuni, Christine C. Winterbourn, Huiyong Yin, Barry Halliwell

Summary: This article discusses the important roles of reactive oxygen species (ROS) in health and disease, and proposes guidelines and best practices for the nomenclature and assessment of ROS, oxidative reactions, and oxidative damage in cells, tissues, and in vivo.

NATURE METABOLISM (2022)

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Article Endocrinology & Metabolism

American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD)

Kenneth Cusi, Scott Isaacs, Diana Barb, Rita Basu, Sonia Caprio, W. Timothy Garvey, Sangeeta Kashyap, Jeffrey I. Mechanick, Marialena Mouzaki, Karl Nadolsky, Mary E. Rinella, Miriam B. Vos, Zobair Younossi

Summary: This article provides evidence-based recommendations for the diagnosis and management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) for endocrinologists, primary care clinicians, and other stakeholders. The guideline includes 34 evidence-based clinical practice recommendations and contains relevant citations.

ENDOCRINE PRACTICE (2022)

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Review Endocrinology & Metabolism

A global view of the interplay between non-alcoholic fatty liver disease and diabetes

Norbert Stefan, Kenneth Cusi

Summary: Non-alcoholic fatty liver disease (NAFLD) has become an epidemic, associated with the increasing prevalence of obesity and type 2 diabetes, and its pathophysiology is closely related to the development of communicable diseases such as COVID-19. Understanding the relationship between diabetes and NAFLD is important for disease treatment. Identifying different pathological mechanisms of NAFLD among different groups of diabetes patients may improve diagnosis and prediction.

LANCET DIABETES & ENDOCRINOLOGY (2022)

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Article Endocrinology & Metabolism

Central obesity, smoking habit, and hypertension are associated with lower antibody titres in response to COVID-19 mRNA vaccine

Mikiko Watanabe, Angela Balena, Dario Tuccinardi, Rossella Tozzi, Renata Risi, Davide Masi, Alessandra Caputi, Rebecca Rossetti, Maria Elena Spoltore, Valeria Filippi, Elena Gangitano, Silvia Manfrini, Stefania Mariani, Carla Lubrano, Andrea Lenzi, Claudio Mastroianni, Lucio Gnessi

Summary: Variables such as increased waist circumference, smoking, hypertension, and longer time elapsed since vaccination were associated with lower antibody titres following COVID-19 mRNA vaccination. This suggests that individuals with central obesity, hypertension, and smoking may benefit from earlier vaccine boosters or different vaccination schedules to ensure adequate immune response.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2022)

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Article Endocrinology & Metabolism

IDF diabetes Atlas: Global estimates of undiagnosed diabetes in adults

Katherine Ogurtsova, Leonor Guariguata, Noel C. W. Barengo, Paz Lopez-Doriga Ruiz, Julian Sacre, Suvi J. Karuranga, Hong J. Sun, Edward Boyko, Dianna Magliano

Summary: According to the 2021 estimates, nearly half of adults with diabetes are unaware of their condition. The highest proportions of undiagnosed diabetes were found in Africa, the Western Pacific, and South-East Asia regions, while the lowest proportion was observed in North America and the Caribbean.

DIABETES RESEARCH AND CLINICAL PRACTICE (2022)

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Article Endocrinology & Metabolism

Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement

Lorenzo M. Donini, Luca Busetto, Stephan C. Bischoff, Tommy Cederholm, Maria D. Ballesteros-Pomar, John A. Batsis, Juergen M. Bauer, Yves Boirie, Alfonso J. Cruz-Jentoft, Dror Dicker, Stefano Frara, Gema Fruehbeck, Laurence Genton, Yftach Gepner, Andrea Giustina, Maria Cristina Gonzalez, Ho-Seong Han, Steven B. Heymsfield, Takashi Higashiguchi, Alessandro Laviano, Andrea Lenzi, Ibolya Nyulasi, Edda Parrinello, Eleonora Poggiogalle, Carla M. Prado, Javier Salvador, Yves Rolland, Ferruccio Santini, Mireille J. Serlie, Hanping Shi, Cornel C. Sieber, Mario Siervo, Roberto Vettor, Dennis T. Villareal, Dorothee Volkert, Jianchun Yu, Mauro Zamboni, Rocco Barazzoni

Summary: Loss of skeletal muscle mass and function is common in individuals with obesity. The co-existence of excess adiposity and low muscle mass/function, known as sarcopenic obesity (SO), negatively impacts patient outcomes. However, the lack of a universally established definition and diagnostic criteria for SO hampers prevention and treatment efforts.

OBESITY FACTS (2022)

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Article Endocrinology & Metabolism

Classification and Diagnosis of Diabetes: Standards of Care in Diabetes-2023

Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Robert A. Gabbay

DIABETES CARE (2023)

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Article Endocrinology & Metabolism

The clinician's guide to prevention and treatment of osteoporosis

M. S. LeBoff, S. L. Greenspan, K. L. Insogna, E. M. Lewiecki, K. G. Saag, A. J. Singer, E. S. Siris

Summary: Osteoporosis is a common metabolic bone disease that often leads to fractures, placing a burden on individuals and the economy. However, many high-risk patients are not screened, diagnosed, or treated effectively. Prevention, diagnosis, and treatment of osteoporosis should be routine in adult healthcare settings.

OSTEOPOROSIS INTERNATIONAL (2022)

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Article Endocrinology & Metabolism

IDF Diabetes Atlas: Estimation of Global and Regional Gestational Diabetes Mellitus Prevalence for 2021 by International Association of Diabetes in Pregnancy Study Group's Criteria

Hui Wang, Ninghua Li, Tawanda Chivese, Mahmoud Werfalli, Hong Sun, Lili Yuen, Cecilia Ambrosius Hoegfeldt, Camille Elise Powe, Jincy Immanuel, Suvi Karuranga, Hema Divakar, NAomi Levitt, Changping Li, David Simmons, Xilin Yang

Summary: The research used IADPSG criteria to estimate the global and regional prevalence of gestational diabetes mellitus (GDM), finding that low-income countries had higher prevalence rates, with the Middle East and North Africa and Southeast Asia having the highest rates.

DIABETES RESEARCH AND CLINICAL PRACTICE (2022)

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