Article
Chemistry, Analytical
Houriyeh Sohrabnavi, Mohammad Mohammadimasoudi, Hassan Hajghassem
Summary: This article reports a liquid crystal-based biosensor for the detection of the main biomarker of Alzheimer's disease, amyloid beta protein. The sensor has a fast response time, high specificity, and a low detection limit.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yuyang Liu, Shiqi Chen, Bing Xiao, Jifeng Chu, Hongkang Wang, Yukun Chen, Tianhao Yao, Aijun Yang, Xiaogang Han, Mingzhe Rong, Xiaohua Wang
Summary: In this study, ultra-large micro-sized Sn3O4 nanosheet hierarchies were prepared and found to possess excellent hydrogen sensing performance and stability. The superior performance of the material was verified through theoretical calculations and practical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Hongchao Deng, Hidefumi Mitsuno, Eri Kuroda, Sawako Niki, Ryohei Kanzaki, Takamichi Nakamoto
Summary: The study proposes a gas-phase odor biosensor for odor mixture quantification based on the relative comparison method, which utilizes cells expressing ORs, liquid thickness control, and liquid exchange. The method overcomes the challenges of biosensor drift and nonlinearity, demonstrating high precision and efficiency in detecting odor mixtures.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Qingfa Gong, Shuyun Meng, Dong Liu, Tianyan You
Summary: In this study, a sensitive PEC apta-sensor was constructed based on a direct Z-scheme heterojunction for the detection of ochratoxin A (OTA). By manipulating the conductivity and hydrophilicity of the materials, the separation of charge carriers and amplification of PEC signal were achieved, enabling the detection of OTA. The developed aptasensor exhibited a wide linear detection range and low detection limit, as well as good selectivity and stability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Bo-Chuan Hsieh, Yan-Ting Li
Summary: Glyphosate monitoring is crucial for environmental protection, biodiversity, human health, and food safety. This study presents an automated screening method using a cost-effective and stable chromophore probe for accurate and rapid quantification of glyphosate in real environmental samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dongdong Liu, Mengpei Wang, Jicao Han, Zhengyu Zhang, Xi Wang
Summary: By decorating tetraphenylethene (TPE) backbones with hydrophilic pyridine ethanol-related groups, a series of novel amphiphilic TPE-based pyridinium salts were synthesized and used as water-soluble turn-on fluorescence probes for latent fingerprint development and antibiotic detection. The method has many advantages, including water solubility, low working concentration, ease of operation, good stability, high safety, high contrast, high sensitivity, and high selectivity.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Mei-Ling Lu, Xin-Yue Zhang, Jun-Qi Song, Qiu-Yi Peng, Han-Xiao Xiao, Yang Yang, Wen-Bin Liang, Shaoguang Sun, Ruo Yuan, Dong-Rong Xiao
Summary: This research demonstrates that the electrical conductivity of HOF-based ECL materials can be significantly improved, leading to enhanced ECL performance. A conductive HOF composite was prepared by growing H3TATB-HOF on a highly conductive PEDOT:PSS polymer, resulting in a remarkable increase in ECL intensity. By combining this improved ECL property with a 3D DNA walker amplification strategy, an ultrasensitive ECL biosensor for microRNA-21 detection was designed.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Kun Yu, Huining Chai, Huayue Sun, Xianxin Xiang, Huili Zhao, Mingwei Tian, Lijun Qu, Guangyao Zhang, Xueji Zhang
Summary: The interactions between water molecules and PMOFs with 15 metal nodes were studied and assessed using the fluorescence method in this study. A model for evaluating the water stability of PMOFs was established, and PMOFs were categorized into three groups based on their fluorescence intensity and kinetic performance in ethanol with different water contents. The water-sensitive magnesium node PMOF showed high sensitivity for detecting trace water in organic media.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Xuyang Zhao, Yuxiang Li, Qi Wang, Man Luo, Yi Zhou, Zhihe Guo, Xiang Wu
Summary: A label-free optical detection method with ultrahigh sensitivity and tunable range was developed to monitor protein conformation changes. The biosensor prototype, constructed with overlapping capillaries, successfully monitored the structural variations of silk proteins. This ultrasensitive biosensor has significant potential for clinical diagnosis, healthcare, pharmaceutical screening, and food security.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Tae Hoon Eom, Sang Eun Lee, Yeong Jae Kim, Sungkyun Choi, Gi Baek Nam, Jung-El Ryu, Tae Hyung Lee, Jin Wook Yang, Sung Hwan Cho, Seung Ju Kim, Sang Eon Jun, Seonyong Lee, Seungsoo Kim, Hee Jung Park, Ho Won Jang
Summary: Chemoresistive humidity sensors based on ultrathin V2O5•nH2O nanobelts show promising performance in real-time breath monitoring, with rapid response and recovery, as well as excellent selectivity to humidity.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Panwang Hu, Jinjin Liu, Changkun Xia, Bangxiang Liu, Hengjia Zhu, Xiangheng Niu
Summary: Given the significant threats of heavy metals to ecological systems and human health, monitoring them is crucial. This study designs a non-redox nanozyme for detecting Hg2+ without interference from redox substances. The approach demonstrates highly sensitive and specific measurement of Hg2+ with excellent reliability and practicability. It is the first study to detect Hg2+ using phosphatase-mimicking nanozymes, inspiring exploration of new analytical methods with non-redox nanozymes.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Chun-Lin Lv, Chang Tang, Hongyan Zhou, Ai-Jun Wang, Jiu-Ju Feng, Tuck Yun Cheang
Summary: In this study, self-supported PtPdMnCoFe high-entropy alloy with nanochain-like internetworks was synthesized and found to be effective in reducing H2O2. It was used as a signal amplifier for the development of a novel label-free electrochemical amperometric immunosensor for ultrasensitive determination of biomarker NSE. The sensor showed a broad linear range and low detection limit for NSE immunoassay, and demonstrated satisfactory results in quantifying NSE in human serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Xiaoyan Lang, Xiaxia Xing, Xinhua Zhao, Lingling Du, Yingying Tian, Zhenxu Li, Xiaoyu Chen, Heliang Fan, Dachi Yang
Summary: This study developed NixCu3_x(HHTP)2/PPy nanocomposites for highly selective and stable H2S sensing at room temperature. The NixCu3_x(HHTP)2/PPy NCPs exhibited excellent selectivity to H2S and maintained a 77.3% response for 70 days at room temperature (- 25 degrees C). The sensor prototypes were able to detect H2S as low as 500 ppb and showed stability against humidity.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anran Gao, Fuwen Wang, Zishuo Fan, Shixing Chen, Kejin Wu
Summary: miRNAs have emerged as promising biomarkers in cancer research, but their detection remains challenging. In this study, a photo response calibration method was proposed to enhance the correlation between a silicon nanowire biosensor and q-PCR for the identification of breast cancer miRNA. The use of an uncharged peptide nucleic acid (PNA) for device modification improved the sensor's sensitivity in detecting low concentration miRNA. The improved biosensor demonstrated favorable selectivity and the ability to detect miRNA directly in authentic clinical samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Zhirui Li, Hui Huang, Danna Zhao, Shunji Chen, Weicheng Cai, Tianlin Tang
Summary: A reliable and high-performance oxygen sensor based on TiO2-decorated GaN nanowires was fabricated, which can operate under UV irradiation at room temperature. Experimental results showed that the sensor had maximum response and a limit of detection as low as 0.45% O2 when the TiO2 film thickness was 5 nm. In addition, the sensor exhibited enhanced O2 sensing with lower wavelength UV illumination. The sensor also demonstrated excellent repeatability, selectivity and long-term stability, making it suitable for various applications in the field of O2 gas sensing.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Pengying Liang, Mengxu Sun, Mengyu Chen, Tong Li, Ting Huang, Qingying Zhou, Chunrong Li, Baoping Xie, Jinxiang Chen, Zong Dai, Yuanxin Tian, Jun Chen
Summary: A novel feedback catalytic hairpin assembly (FCHA) was proposed for mRNA imaging in living cells, which demonstrated improved reaction kinetics and sensitivity compared to traditional CHA, and could be used for real-time imaging and indication of changes in mRNA expression.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ruili Wang, Lan Xu, Jishan Li
Summary: A novel visualized chemiluminescence sensor array was developed, which combines the cascade amplification of CHA and HCR with the catalytic activity of G-quadruplex DNAzyme, for simultaneous detection of four cancer-associated miRNAs.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
