Dermatology

Letter Dermatology

Safety of dupilumab in atopic patients during COVID-19 outbreak

Maddalena Napolitano, Cataldo Patruno, Angelo Ruggiero, Mariateresa Nocerino, Gabriella Fabbrocini

JOURNAL OF DERMATOLOGICAL TREATMENT (2022)

Letter Critical Care Medicine

Machine learning for burns clinical care: Opportunities & challenges

Mohammadreza Mobayena, Mohammad Javad Ghazanfaria, Alireza Feizkhaha, Samad Karkhaha, Amir Emami Zeydid

Review Dermatology

Alopecia areata: Current understanding of the pathophysiology and update on therapeutic approaches, featuring the Japanese Dermatological Association guidelines

Masahiro Fukuyama, Taisuke Ito, Manabu Ohyama

Summary: Alopecia areata is characterized by autoimmune response to hair follicles, potentially triggered by factors like viral infection and various inflammatory mediators. Psychological stress plays a role in the pathogenesis, and besides treating hair loss symptoms, managing psychological comorbidities is also crucial in AA management. Evidenced-based medicine for AA is limited, but novel therapeutic approaches are emerging.

JOURNAL OF DERMATOLOGY (2022)

Article Dermatology

Dermatological consultations in the COVID-19 era: is teledermatology the key to social distancing? An Egyptian experience

Pakinam I. N. Mostafa, Amira Ali Hegazy

Summary: Teledermatology plays an important role during the COVID-19 pandemic, effectively triaging and treating dermatological conditions, reducing the risk of infection. Patients show overall satisfaction with teledermatology services.

JOURNAL OF DERMATOLOGICAL TREATMENT (2022)

Article Dermatology

Drug Survival Associated With Effectiveness and Safety of Treatment With Guselkumab, Ixekizumab, Secukinumab, Ustekinumab, and Adalimumab in Patients With Psoriasis

Zenas Z. N. Yiu, Gabrielle Becher, Brian Kirby, Philip Laws, Nick J. Reynolds, Catherine H. Smith, Richard B. Warren, Christopher E. M. Griffiths

Summary: The results of this cohort study suggest that guselkumab had the highest drug survival among the included biologics for treating psoriasis in terms of effectiveness, and guselkumab had the highest drug survival for safety compared with other biologics except ustekinumab.

JAMA DERMATOLOGY (2022)

Letter Dermatology

Development of psoriasis during treatment with dupilumab: A systematic review

Caitlin M. Brumfiel, Meera H. Patel, Matthew J. Zirwas

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Review Dermatology

Treatment of pediatric alopecia areata: A systematic review

Virginia R. Barton, Atrin Toussi, Smita Awasthi, Maija Kiuru

Summary: This systematic review evaluated the evidence of current treatment modalities for pediatric alopecia areata (AA). Topical corticosteroids were found to be the preferred first-line treatment for pediatric AA, followed by contact immunotherapy. More clinical trials and comparative studies are needed to guide the management of pediatric AA and explore the potential use of other therapies, such as Janus kinase inhibitors.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Letter Dermatology

Bullous pemphigoid after anti-programmed death-1 therapy: A retrospective case-control study evaluating impact on tumor response and survival outcomes

Caroline A. Nelson, Sean Singer, Tianqi Chen, Ashleigh Eberly Puleo, Christine G. Lian, Erin X. Wei, Anita Giobbie-Hurder, Arash Mostaghimi, Nicole R. LeBoeuf

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Review Dermatology

The impact of resveratrol on skin wound healing, scarring, and aging

Andrzej Hecker, Marlies Schellnegger, Elisabeth Hofmann, Hanna Luze, Sebastian Philipp Nischwitz, Lars-Peter Kamolz, Petra Kotzbeck

Summary: Resveratrol is a powerful antioxidant that may aid in wound healing and prevent skin aging. Current research suggests that resveratrol could be a feasible treatment approach, but further studies are needed to confirm its effects.

INTERNATIONAL WOUND JOURNAL (2022)

Review Dermatology

Pyoderma Gangrenosum: An Updated Literature Review on Established and Emerging Pharmacological Treatments

Carlo Alberto Maronese, Matthew A. Pimentel, May M. Li, Giovanni Genovese, Alex G. Ortega-Loayza, Angelo Valerio Marzano

Summary: Pyoderma gangrenosum is a rare inflammatory skin disease characterized by painful, rapidly evolving ulcers. The pathogenesis involves dysregulation of both innate and adaptive immunity. Validated diagnostic criteria and effective treatments are currently lacking.

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2022)

Article Dermatology

Treatment of pemphigus vulgaris and foliaceus with efgartigimod, a neonatal Fc receptor inhibitor: a phase II multicentre, open-label feasibility trial

M. Goebeler, Z. Bata-Csorgo, C. De Simone, B. Didona, E. Remenyik, N. Reznichenko, J. Stoevesandt, E. S. Ward, W. Parys, H. de Haard, P. Dupuy, P. Verheesen, E. Schmidt, P. Joly

Summary: Efgartigimod exhibited good tolerability and significant early disease control effects in treating pemphigus, leading to complete clinical remission in some patients.

BRITISH JOURNAL OF DERMATOLOGY (2022)

Review Dermatology

SARS-CoV-2 vaccine-related cutaneous manifestations: a systematic review

Gianluca Avallone, Pietro Quaglino, Francesco Cavallo, Gabriele Roccuzzo, Simone Ribero, Iris Zalaudek, Claudio Conforti

Summary: This study provides an extensive overview of SARS-CoV-2 vaccine-related skin manifestations through a systematic review of 229 articles. The study identifies various skin reactions such as local injection-site reactions, rashes, urticarial rashes, angioedema, and herpes zoster. The research suggests that cutaneous adverse reactions following SARS-CoV-2 vaccine administration are infrequent and not life-threatening, but monitoring and evaluation of the skin should still be provided for vaccinated patients.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2022)

Letter Dermatology

The impact of COVID-19 infection on patients with psoriasis treated with biologics: an Italian experience

Angelo Ruggiero, Fabrizio Martora, Vincenzo Picone, Luca Potestio, Elisa Camela, Teresa Battista, Gabriella Fabbrocini, Matteo Megna

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2022)

Article Dermatology

Ixekizumab and brodalumab indirect comparison in the treatment of moderate to severe psoriasis: Results from an Italian single-center retrospective study in a real-life setting

Matteo Megna, Luca Potestio, Elisa Camela, Gabriella Fabbrocini, Angelo Ruggiero

Summary: This study compared the efficacy and safety of Ixekizumab and Brodalumab in patients with psoriasis, and found that they were comparable in terms of effectiveness and safety.

DERMATOLOGIC THERAPY (2022)

Letter Dermatology

Reply to 'Cutaneous adverse effects of the available COVID-19 vaccines in India: A questionnaire-based study'. by Bawane J et al

L. Potestio, L. Genco, A. Villani, C. Marasca, G. Fabbrocini, L. Fornaro, A. Ruggiero, F. Martora

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2022)

Review Dermatology

Association of Risk of Incident Venous Thromboembolism With Atopic Dermatitis and Treatment With Janus Kinase Inhibitors A Systematic Review and Meta-analysis

Tai-Li Chen, Ling-Ling Lee, Huei-Kai Huang, Li-Yu Chen, Ching-Hui Loh, Ching-Chi Chi

Summary: The systematic review and meta-analysis indicated that there is no increased risk of VTE associated with AD or treatment with JAK inhibitors based on the currently available evidence.

JAMA DERMATOLOGY (2022)

Article Dermatology

COVID-19 related anagen effluvium

Mohammed Shanshal

Summary: This article presents a case of COVID-19 patient with anagen effluvium, a type of hair loss, along with extensive urticaria and maculopapular rash. The patient showed response to low dose systemic steroids treatment.

JOURNAL OF DERMATOLOGICAL TREATMENT (2022)

Letter Dermatology

Vesiculobullous skin reactions induced by COVID-19 mRNA vaccine: report of four cases and review of the literature

P. Coto-Segura, M. Fernandez-Prada, M. Mir-Bonafe, B. Garcia-Garcia, I. Gonzalez-Iglesias, P. Alonso-Penanes, M. Gonzalez-Guerrero, A. Gutierrez-Palacios, E. Miranda-Martinez, F. Martinon-Torres

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2022)

Article Dermatology

Deucravacitinib in Moderate to Severe Psoriasis: Clinical and Quality-of-Life Outcomes in a Phase 2 Trial

Diamant Thaci, Bruce Strober, Kenneth B. Gordon, Peter Foley, Melinda Gooderham, Akimichi Morita, Kim A. Papp, Lluis Puig, M. Alan Menter, Matthew J. Colombo, Yedid Elbez, Renata M. Kisa, June Ye, Andrew A. Napoli, Lan Wei, Subhashis Banerjee, Joseph F. Merola, Alice B. Gottlieb

Summary: Deucravacitinib has shown therapeutic benefit in adults with moderate to severe plaque psoriasis, improving clinical outcomes and quality of life. It has the potential to become a promising new oral therapy for this condition.

DERMATOLOGY AND THERAPY (2022)

Editorial Material Dermatology

American Academy of Dermatology Guidelines: Awareness of comorbidities associated with atopic dermatitis in adults

Dawn M. R. Davis, Aaron M. Drucker, Ali Alikhan, Lionel Bercovitch, David E. Cohen, Jennifer M. Darr, Lawrence F. Eichenfield, Lindsy Frazer-Green, Amy S. Paller, Jonathan Silverberg, Anne Marie Singh, Robert Sidbury

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)