Article
Oncology
Lirui Zhang, Qiaoshi Xu, Zhien Feng
Summary: This study presents a comprehensive clinical, genomic, and transcriptomic analysis of primary ghost cell odontogenic carcinoma (GCOC). The results provide the first comprehensive molecular atlas for primary GCOC, including previously identified CTNNB1 mutation and novel alterations in MAP3K, EP300, and the 22q11.21 region. The transcriptome analysis reveals significant involvement of cytokine-cytokine receptor interaction and the PI3K-Akt signaling pathway. More GCOC cases should be compared to validate these findings for accurate clinical guidance.
Article
Dentistry, Oral Surgery & Medicine
Xiaoyue Guan, Chen Shi, Yuting Wang, Yani He, Yingxue Li, Yao Yang, Wenli Mu, Wenlan Li, Tiezhou Hou
Summary: The study revealed that Gremlin1 expression levels are significantly increased in periapical lesions and may be positively correlated with IL-18 levels. Blocking Gremlin1 can significantly suppress bone resorption loss and restrain inflammatory status by affecting the activation levels of phosphorylated-CREB, ICAM-1, VCAM-1, IL-18.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Meimei Cui, Jinling Cheng, Huijuan Cheng, Ming Zhao, Dan Zhou, Min Zhang, Jingjing Jia, Limei Luo
Summary: This study explored the characteristics of human papillomavirus (HPV) in oropharyngeal carcinoma (OPC) and found that high-risk HPV infection is common in OPC patients, with higher prevalence in North America, Oceania, and Europe. Females and older patients are more susceptible to infection. Tonsil and base of tongue are the most frequent sites of infection. This study provides important theoretical basis for the prevention and treatment of OPC.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Giovanna Iezzi, Barbara Zavan, Morena Petrini, Letizia Ferroni, Tania Vanessa Pierfelice, Ugo D'Amora, Alfredo Ronca, Emira D'Amico, Carlo Mangano
Summary: This study characterized the surface topography and evaluated the biological responses of various cells to a novel 3D-printed dental implant. The surface of the implant showed a highly interconnected porous architecture and roughness, leading to good adhesion and growth of human oral osteoblasts, gingival fibroblasts, mesenchymal stem cells, and monocytes. These findings suggest that this 3D-printed implant has excellent potential for clinical applications.
JOURNAL OF DENTISTRY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Katsuhisa Sekido, Minami Asakura, Hidetake Tachinami, Makoto Noguchi
Summary: This report presents a case of T-cell dominant polymorphic lymphoproliferative disorder associated with periimplantitis due to long-term methotrexate administration. The patient experienced relief from pain after methotrexate withdrawal, but bone exposure persisted.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Chieko Michikawa, Toshiyuki Izumo, Tetsuya Yoda, Narikazu Uzawa
Summary: This study aimed to investigate the association between extranodal extension (ENE) and tumor invasion status of metastatic lymph node in oral cavity squamous cell carcinoma (OSCC) patients, and its association with clinical outcomes.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Seiji Baba, Kyoko Ishimaru, Eiji Ito, Saki Goto, Keizo Kato, Yoichi Yamada
Summary: This article reports a rare case of leiomyosarcoma metastasizing to the sublingual region, which underwent multiple resection surgeries. No tumor recurrence was observed in the sublingual region after the surgeries.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Masato Narita, Masae Yamamoto, Takashi Takaki, Masashi Iwamoto, Mamoru Wakoh, Takashi Yakushiji, Akira Katakura, Masayuki Takano, Takashi Kamio
Summary: This study reviews the diseases detected as incidental findings (IFs) during TMJ MR imaging and provides case reports including the detection of IFs.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Takumi Sato, Eri Kitaya, Katsumitsu Shimada, Michiko Yoshizawa, Yuji Kurihara, Hiromasa Hasegawa
Summary: Hobnail hemangioma is a rare vascular tumor that typically occurs in young or middle-aged individuals. This study reports an unusual case of hobnail hemangioma on the tongue with pyogenic granuloma-like appearances. The patient underwent successful surgery and showed no recurrence after 2 years.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Motohiro Tanaka, Hitoshi Sato, Mariko Asakura, Yuzo Abe, Yuji Kurihara, Tatsuo Shirota
Summary: Osteochondroma of the condyle can result in facial asymmetry, jaw-movement disorders, and malocclusion. This case report presents a 28-year-old man with gradually increasing facial asymmetry for 5 years. Surgical intraoperative navigation was used to perform condylectomy and vertical ramus osteotomy, achieving satisfactory results.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Giliano Nicolini Verzeletti, Eduardo Jose Gaio, Keilla Gomes Machado, Tobias Rauber Spuldaro, Clarissa Favero Demeda, Rafaele Frassini, Andre Felipe Streck, Sidnei Moura E. Silva, Cassiano Kuchenbecker Rosing, Joao Antonio Pegas Henriques, Mariana Roesch-Ely
Summary: This study investigates the effects of D. anceps seaweed on ligature-induced experimental periodontitis in rats. The results show that D. anceps can modulate the inflammatory response and have potential therapeutic effects for periodontitis.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Elham Mohebbi, Zainab Alimoradi, Laura S. Rozek, Azadeh Mohebbi, Elahe Jafari
Summary: This study conducted a systematic review and meta-analysis to investigate the risk of head and neck cancer among opium users. The findings showed a significant correlation between opium use and the development of head and neck cancers, particularly lip and oral cavity cancers and laryngeal cancer. This highlights the importance of further research and targeted preventive measures to address this concerning association.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Junkang Quan, Yang Liu, Lingli Ji, Yuming Zhao, Shuguo Zheng
Summary: This study identified a new DLX3 gene mutation in a Chinese family with enamel dysplasia and found that this mutation may affect ameloblast differentiation by inhibiting the transcriptional activity of Amelx/Odam/Klk4, thereby interfering with enamel formation.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Doris Haydee Rosero Salazar, Sydney Honnlee, Zi-Jun Liu
Summary: This study analyzed the dynamics and coordination of oropharyngeal muscles during natural chewing and swallowing, revealing the key role of palatal and pharyngeal muscles in chewing and the simultaneous changes in muscle activity and respiratory cycle during these processes.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Mari Shibata, Hiroyuki Yoshitake, Kou Kayamori, Tohru Ikeda, Motoko Seki, Tetsuya Yoda
Summary: Neoplastic lesions in the oral and maxillofacial regions of infants are rare, and a definitive diagnosis based on histopathological examination should be considered for cases that are difficult to diagnose clinically and radiographically.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Takasuke Usuki, Kohei Kawamura, Takayuki Kurimoto, Hironobu Kobashi, Kanemitsu Shirasuna, Hideo Yoshioka
Summary: Intramuscular lipoma is rare in the oral region, and its cause is unknown. This report presents a case of intramuscular lipoma-like lesion in the right cheek. The use of REGROTH (R) in the surgical procedure may be involved in tumor development.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Kotoko Imai, Takanori Sugiura, Miki Sato, Homare Kawachi
Summary: Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a progressive mitochondrial disease characterized by multiple cerebral infarctions, muscle weakness, neuropathy, intellectual regression, and other symptoms. This study reports a case of a diabetic patient with MELAS who underwent oral treatment for weakened facial muscles, showing good progress initially but later refusing treatment and experiencing rapid deterioration leading to death.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Chang Zeng, Pei Hu, Colin P. Egan, Brian E. Bergeron, Franklin Tay, Jingzhi Ma
Summary: The study compared the bacteria debridement efficacy of the first and second generations of sonic root canal irrigant activation systems. The results showed that activation of 2% NaOCl with either EndoActivator or SmartLite Pro EndoActivator significantly reduced the overall intracanal bacterial load compared to syringe-side-vented needle delivery. However, delivering 2% NaOCl for 5 minutes using the syringe-side-vented needle produced better bacteria debridement than either sonic agitation system.
JOURNAL OF DENTISTRY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Jose Wilson Noleto, Nathalie Murielly Rolim de Abreu, Raissa Leitao Guedes, Pollianna Muniz Alves, Pedro Paulo de Andrade Santos
Summary: This study describes a rare case of cystic calcifying epithelial odontogenic tumor (CEOT). The tumor presented as a mixed radiolucent-radiopaque lesion in the posterior region of the maxilla, accompanied by a missing upper second molar. Histopathological examination revealed calcification in the fibrous capsule of the cystic lesion, as well as other characteristic features.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Sachiko Yamasaki, Ryouji Tani, Souichi Yanamoto
Summary: Cranial base invasion can have a serious impact on patients' quality of life. However, a combination chemotherapy regimen of nivolumab followed by cetuximab and paclitaxel has shown promising efficacy in treating recurrent lip cancer with skull base invasion, achieving complete response.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY
(2024)
