Critical Care Medicine

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Article Critical Care Medicine

The incidence, predictors, and causes of cardiac arrest in United States emergency departments

Shu-Hsien Hsu, Chih-Wei Sung, Tsung-Chien Lu, Chih-Hung Wang, Eric H. Chou, Chia-Hsin Ko, Chien-Hua Huang, Chu -Lin Tsai

Summary: Emergency department cardiac arrest (EDCA) during emergency department (ED) visits in the U.S. is associated with high mortality rates and poor neurological outcomes. This retrospective cohort study analyzed data from the 2019 Nationwide Emergency Department Sample (NEDS) to investigate the incidence, risk factors, and causes of EDCA. The study found that certain demographic factors, comorbidities, hospital characteristics, and specific medical conditions were associated with a higher or lower risk of EDCA. Septicemia, acute myocardial infarction, respiratory failure, and drug overdose were identified as the predominant causes of EDCA.

RESUSCITATION PLUS (2024)

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Letter Critical Care Medicine

A resuscitation educational tool with a smartphone videogame cartoon character

Yosuke Homma

RESUSCITATION PLUS (2024)

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Article Critical Care Medicine

Effects of different positive end-expiratory pressure titration strategies on mechanical power during ultraprotective ventilation in ARDS patients treated with veno-venous extracorporeal membrane oxygenation: A prospective interventional study

Christoph Boesing, Laura Schaefer, Peter T. Graf, Paolo Pelosi, Patricia R. M. Rocco, Thomas Luecke, Joerg Krebs

Summary: In ARDS patients treated with VV ECMO, adjusting PEEP to 10 cmH(2)O can reduce MP, improve hemodynamic parameters, and increase oxygen delivery.

JOURNAL OF CRITICAL CARE (2024)

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Article Critical Care Medicine

Previously healthy adults among septic patients: Population-level epidemiology and outcomes

Lavi Oud, John Garza

Summary: Previously healthy septic patients have lower short-term mortality compared to those with comorbid conditions. This finding is consistent in both community-onset and hospital-onset sepsis.

JOURNAL OF CRITICAL CARE (2024)

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Article Critical Care Medicine

Prospective evaluation of bleeding risk among thrombocytopenic patients admitted in intensive care unit

Geoffroy Hariri, Vincent Belossi, Louis Perol, Louai Missri, Paul Gabarre, Vincent Bonny, Tomas Urbina, Jean-Luc Baudel, Bertrand Guidet, Jeremie Joffre, Eric Maury, Guillaume Dumas, Hafid Ait-Oufella

Summary: This study found that plasma urea levels and the presence of skin purpura are helpful in identifying thrombocytopenic patients at high-risk of bleeding during ICU stay.

JOURNAL OF CRITICAL CARE (2024)

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Article Critical Care Medicine

Healed ORIF in a fibula fracture - Hardware removal or hardware retention for the fibula in a patient with minor symptoms?

Gareth Rooke, Paul Sharplin, Richard Buckley

Summary: A 31-year-old female suffered a right fibula fracture with deltoid ligament injury after falling while climbing on wet rocks. She had ORIF surgery and recovered well, but has developed vague pain and hardware sensation at the lateral ankle 6 months later. Her past medical history includes breast reduction surgery and vaginal delivery, and she has a social history of alcohol consumption and past recreational drug use.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2024)

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Article Critical Care Medicine

Neuromuscular blockade and oxygenation changes during prone positioning in COVID-19

Thomas C. Rollinson, Luke A. McDonald, Joleen Rose, Glenn Eastwood, Rahul Costa-Pinto, Lucy Modra, Akinori Maeda, Zoe Bacolas, James Anstey, Samantha Bates, Scott Bradley, Jodi Dumbrell, Craig French, Angaj Ghosh, Kimberley Haines, Tim Haydon, Carol L. Hodgson, Jennifer Holmes, Nina Leggett, Forbes McGain, Cara Moore, Kathleen Nelson, Jeffrey Presneill, Hannah Rotherham, Simone Said, Meredith Young, Peinan Zhao, Andrew Udy, Ary Serpa Neto, Anis Chaba, Rinaldo Bellomo

Summary: Neuromuscular blockers (NMBs) used during prone positioning in COVID-19 ARDS patients can improve oxygenation and have a sustained effect upon returning to supine position.

JOURNAL OF CRITICAL CARE (2024)

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Review Critical Care Medicine

Lessons learned from biomechanical studies on cephalomedullary nails for the management of intertrochanteric fractures. A scoping review

Jorge Mayor, Vera Birgel, Jan-Dierk Clausen, Goekmen Aktas, Stephan Sehmisch, Ann-Kathrin Einfeldt, Vasilis Giannoudis, Ahmed H. K. Abdelaal, Emmanouil Liodakis

Summary: This study provides a comprehensive overview of biomechanical research on the treatment of intertrochanteric fractures using cephalomedullary devices. Through a systematic literature search and synthesis analysis, the study highlights the need for standardization in biomechanical studies, and suggests strategies to enhance construct stability. The findings emphasize the importance of further research and meta-analyses to establish standardized protocols and enhance reliability.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2024)

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Article Critical Care Medicine

Passive leg raising test induced changes in plethysmographic variability index to assess fluid responsiveness in critically ill mechanically ventilated patients with acute circulatory failure

Jihad Mallat, Malcolm Lemyze, Marc-Olivier Fischer

Summary: In mechanically ventilated patients with acute circulatory failure, changes in PVI induced by PLR accurately predict fluid responsiveness.

JOURNAL OF CRITICAL CARE (2024)

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Article Critical Care Medicine

National analysis of over and under-triage rates in relation to trauma population risk factors and associated outcomes across various levels trauma centers

Jeffrey Hayashi, Maveric Abella, Denise Nunez, Noah Alter, Jason Kim, Abigail Rosander, Adel Elkbuli

Summary: This study evaluates the rates of over-triage and under-triage in trauma patients nationwide, as well as the associated risk factors and outcomes. The findings suggest that Pacific Islander and American Indian patients, Medicare beneficiaries, and patients treated at level II and III trauma centers are more likely to be over-triaged. Hispanic patients and privately insured patients, on the other hand, have a higher risk of under-triage.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2024)

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Article Critical Care Medicine

Management of swallowing disorders in ICU patients - A multinational expert opinion

Rudolf Likar, Ilia Aroyo, Katrin Bangert, Bjorn Degen, Rainer Dziewas, Oliver Galvan, Michaela Trapl Grundschober, Markus Kostenberger, Paul Muhle, Joerg C. Schefold, Patrick Zuercher

Summary: This article presents expert opinions on the diagnosis and management of dysphagia in ICU patients. The panel suggests adopting clinical algorithms to promote standardized and high-quality care, and proposes two clinical management algorithms to improve early detection and effective treatment of dysphagia in ICU patients.

JOURNAL OF CRITICAL CARE (2024)

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Article Critical Care Medicine

A new method regulates bone fracture tissue exosome lncRNA-mRNA to promote mesenchymal stem cell proliferation and migration

Dong Wang, Shuo Diao, Xiaobin Zhou, Junlin Zhou, Yang Liu

Summary: This study discussed the role of fracture site tissue exosomes lncRNAs-mRNAs networks on post-injury adaptation (PIA) promoting bone mesenchymal stem cells (BMSCs) proliferation and migration. The results confirmed that PIA accelerated BMSCs proliferation and migration, and identified tissue exosomes as the key factor in this process. By analyzing the tissue exosomes lncRNAs-mRNAs networks, several hub genes, such as Akt1, Actb, and Uba52, were identified, and Kif11 was found to be a key gene in BMSCs regulated by tissue-derived exosomes of PIA treated rats.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2024)

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Article Anesthesiology

A randomized controlled trial of spinal morphine with an enhanced recovery pathway and its effect on duration of analgesia after cesarean delivery

Maria C. Borrelli, Andrew J. Sprowell, Anna Moldysz, Mohammed Idris, Samantha L. Armstrong, John J. Kowalczyk, Yunping Li, Philip E. Hess

Summary: This study investigates the relationship between intrathecal morphine and enhanced recovery pathways after cesarean delivery. The results indicate that lower doses provide shorter duration of analgesia and higher pain scores. In contrast, a dose of 250 mcg offers longer-lasting pain relief with similar side effects. Both 150 mcg and 250 mcg doses allow a majority of patients to avoid additional opioid use within 72 hours.

ANAESTHESIA CRITICAL CARE & PAIN MEDICINE (2024)

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Article Anesthesiology

Pain during cesarean delivery: A patient-related prospective observational study assessing the incidence and risk factors for intraoperative pain and intravenous medication administration

Jose Sanchez, Rohan Prabhu, Jean Guglielminotti, Ruth Landau

Summary: This study evaluates the incidence of self-reported pain and the administration of intravenous medication (IVM) during cesarean delivery. The results show that 11.5% of women reported pain during the procedure, and a proportion of them received analgesic IVM. Risk factors for pain included substance use disorder and intrapartum epidural extension.

ANAESTHESIA CRITICAL CARE & PAIN MEDICINE (2024)

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Article Critical Care Medicine

A comparison between ilioinguinal and modified Stoppa approach in anterior column acetabular fractures

M. Scrivano, A. Vadal, G. Fedeli, R. Di Niccolo, D. Topa, S. Porcino, F. Pallotta, A. De Carli

Summary: This study compares the outcomes and complications of Ilioinguinal versus modified Stoppa approach in Open Reduction and Internal Fixation (ORIF) of anterior column acetabulum fractures. The results show that the modified Stoppa approach has a shorter operative time, less intra-operative blood loss, and fewer complications. The ilioinguinal approach achieves better anatomic reduction. However, there were no significant differences in terms of vascular lesions, clinical and functional outcomes between the two groups.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2024)

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Article Critical Care Medicine

Analysis of dental traumatic patterns in standing electric scooter-related accidents

Youngmin Kwon, Jihye Lim, Chunui Lee

Summary: This study aims to investigate dental traumatic injuries related to standing electric scooters and compare them with injuries caused by other factors. The results indicate that crown-root fractures and avulsions are more common in electric scooter accidents. Additionally, relatively minor dental injuries, such as concussions and subluxations, are more likely to occur as combined injuries in electric scooter accidents. The study suggests the need for strengthened policies and enforcement of laws to prevent severe dental and craniofacial trauma associated with electric scooter use.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2024)

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Article Critical Care Medicine

Operative outcomes and fracture patterns in dysmorphic sacrums

Alejandro Alejandrez, Motasem Refaat, Yeng Vue

Summary: This study aims to assess the rate of operative fixation of sacral fractures in pelvises with dysmorphic and nondysmorphic sacrums, as well as whether a difference exists in fracture morphology between groups. The study found no statistical difference in operative fixation rates between pelvises with dysmorphic and nondysmorphic sacrums, but a difference in fracture patterns was observed.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2024)

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Article Critical Care Medicine

Malglycemia in the critical care setting. Part II: Relative and absolute hypoglycemia

Greg Roberts, James S. Krinsley, Jean-Charles Preiser, Stephen Quinn, Peter R. Rule, Michael Brownlee, Guillermo E. Umpierrez, Irl B. Hirsch

Summary: Relative hypoglycemia was commonly seen in patients with HbA1c ≥ 8% and was independently associated with mortality. Absolute hypoglycemia was associated with mortality regardless of HbA1c.

JOURNAL OF CRITICAL CARE (2024)

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Letter Critical Care Medicine

Letter to the editor: Etomidate as an induction agent for endotracheal intubation in critically ill patients: A meta-analysis of randomized trials

Cassidy Lavin, Quincy K. Tran, Jessica Downing, Ali Pourmand

JOURNAL OF CRITICAL CARE (2024)

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Review Critical Care Medicine

Compression screw internal fixation versus non-weight-bearing cast immobilization for Jones fractures in children

Yuwei Wen, Danjiang Zhu, Qiang Wang, Baojian Song, Wei Feng

Summary: This study compared the clinical outcomes of compression screw and non-weight-bearing techniques in treating pediatric Jones fractures. The results showed that compared to non-weight-bearing techniques, compression screw fixation can shorten the radiographic union time, immobilization time, and facilitate earlier return to full weight bearing and daily life. We recommend the use of compression screw fixation for widely displaced fractures and school-age active adolescents.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2024)

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