Clinical Neurology

Article Clinical Neurology

The impact of sleep disturbances on suicide risk among people living HIV: An eleven-year national cohort

Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko

Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

The role of family accommodation in child posttraumatic stress symptoms and functional impairment in the context of cognitive behavioral therapy

Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch

Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

A posterior-alpha ageing network is differentially associated with antidepressant effects of venlafaxine and rTMS

Hannah Meijs, Helena Voetterl, Alexander T. Sack, Hanneke van Dijk, Bieke De Wilde, Jan Van Hecke, Peter Niemegeers, Evian Gordon, Jurjen J. Luykx, Martijn Arns

Summary: This study used a polygenic score (PGS) and electroencephalography (EEG) data analysis to identify potential predictors for treatment outcomes in major depressive disorder (MDD). The results suggest the existence of a stable EEG network related to antidepressant-response that has potential as a predictor for MDD treatment, particularly in the case of venlafaxine.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2024)

Article Clinical Neurology

Characterizing depression after traumatic brain injury using a symptom-oriented approach

Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz

Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Association between depression status and hearing loss among older adults: The role of outdoor activity engagement

Zhihong Lu, Dongyue Yu, Lijun Wang, Peipei Fu

Summary: This study finds that more than half of Chinese older adults over 60 suffer from hearing loss, which may increase the risk of depression. Outdoor activity engagement plays a role in alleviating depression symptoms, especially in the areas of entertainment and physical activities.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder

Blaise L. Worden, David F. Tolin, Michael C. Stevens

Summary: A potential barrier to effective cognitive-behavioral therapy for patients with hoarding disorder is treatment retention and compliance. This study found that abnormal brain activity in regions related to executive functioning, such as the insula, parietal, and premotor areas, was significantly associated with treatment compliance in hoarding disorder patients.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Discovery of depression-associated factors among childhood trauma victims from a large sample size: Using machine learning and network analysis

Yu Jin, Shicun Xu, Zhixian Shao, Xianyu Luo, Yinzhe Wang, Yi Yu, Yuanyuan Wang

Summary: This study utilized the XGBoost model and network analysis to identify critical factors related to depression and explore their associations. The results revealed significant positive associations between anxiety and obsessive compulsive disorder (OCD), anxiety and post-traumatic stress disorder (PTSD), social anxiety disorder (SAD) and appearance anxiety, as well as negative associations between sleep quality and anxiety, sleep quality and PTSD among individuals with childhood trauma experiences and depression.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

White matter integrity in bipolar disorder investigated with diffusion tensor magnetic resonance imaging and fractal geometry

Letizia Squarcina, Susanna Lucini Paioni, Marcella Bellani, Maria Gloria Rossetti, Josselin Houenou, Mircea Polosan, Mary L. Phillips, Michele Wessa, Paolo Brambilla

Summary: In this study, the state of white matter structures in bipolar disorder patients was investigated using TBSS and FD analyses. The results showed diffusion abnormalities primarily located in the temporo-parietal network, while no significant differences were found in the morphological complexity of white matter structures. Individual patients showed localized significant deviations in fractal dimension values.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Clustered health risk behaviors with comorbid symptoms of anxiety and depression in young adults: Moderating role of inflammatory cytokines

Meng Wang, Tingting Li, Yang Xie, Dan Zhang, Yang Qu, Shuang Zhai, Xingyue Mou, Yajuan Yang, Liwei Zou, Shuman Tao, Fangbiao Tao, Xiaoyan Wu

Summary: This study finds that clustered health risk behaviors have a significant impact on mental health among young adults, and inflammatory cytokines play a negative moderating role in this relationship.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Purpose in life and stress: An individual-participant meta-analysis of 16 samples

Angelina R. Sutin, Martina Luchetti, Yannick Stephan, Amanda A. Sesker, Antonio Terracciano

Summary: The study found that having a purpose in life is associated with less subjective stress. This association is similar across different age, sex, race, ethnicity, and education backgrounds, and is not moderated by psychological distress. The findings also suggest that this association is generally consistent across different cultural contexts. Therefore, having a purpose in life may contribute to better mental and physical health by reducing subjective stress.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Profiles of intolerance of uncertainty, separation anxiety, and negative affectivity in emerging adulthood: A person-centered approach

Sara Iannattone, Silvia Spaggiari, Daniela Di Riso, Gioia Bottesi

Summary: This study aimed to explore the psychological profiles of IU, separation anxiety symptoms, and negative affectivity in Italian young adults and compare them in terms of psychological and psychosocial characteristics.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Small Steps over time: A longitudinal usability test of an automated interactive text messaging intervention to support self-management of depression and anxiety symptoms

Jonah Meyerhoff, Miranda Beltzer, Sarah Popowski, Chris J. Karr, Theresa Nguyen, Joseph J. Williams, Charles J. Krause, Harsh Kumar, Ananya Bhattacharjee, David C. Mohr, Rachel Kornfield

Summary: This study examines the effectiveness of an 8-week automated interactive text messaging intervention for depression and anxiety. The results show high engagement and usability of the intervention, with significant reductions in depression symptoms. However, reductions in anxiety symptoms were not significant. Participants suggested improvements for the intervention.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Quantile regression to explore association of sleep duration with depression among adults in NHANES and KNHANES

Lulu Pan, Chen Huang, Yahang Liu, Jiahuan Peng, Ruilang Lin, Yongfu Yu, Guoyou Qin

Summary: This study used quantile regression to evaluate the associations between sleep duration and depression across the entire distribution of depression severity. The findings revealed that the association between sleep duration and depression was more pronounced at higher levels of depression severity. Additionally, the association between short sleep duration and depression was stronger in females and individuals with chronic diseases.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Exploring gender differences in risk factors for self-harm in adolescents using data from the Millennium Cohort Study

Emma Diggins, Hein Heuvelman, Mar Pujades-Rodriguez, Allan House, David Cottrell, Cathy Brennan

Summary: Self-harm is common in young people, with girls having higher rates than boys. Gender differences in exposure to risk factors such as adverse events and problematic interpersonal relationships, emotional wellbeing, and social media use may contribute to the increased risk of self-harm in girls. Further research is needed to understand why these differences exist and develop gender-specific approaches to self-harm management.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Association between sleep hours and changes in cognitive function according to the morningness-eveningness type: A population-based study

Eun Kyoung Ahn, Kyuhyun Yoon, Ji-Eun Park

Summary: This study investigated the impact of different sleep hours on the risk of cognitive decline, taking into account morningness-eveningness types. The findings suggest that the morningness group had the lowest risk of cognitive decline within the 7-9 hour sleep duration. However, when considering sleep quality, the optimal sleep duration varied among different types.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Current maternal depression associated with worsened children's social outcomes during middle childhood: Exploring the role of positive affect socialization

Salome Vanwoerden, Jennifer S. Silk, Erika E. Forbes, Judith K. Morgan

Summary: This study evaluates the relationship between maternal depression history and current severity with positive affect socialization and offspring's social outcomes. The results suggest that current level of maternal depression is associated with more social problems and lower quality of best friendships in children. However, positive affect socialization is not related to maternal depression history or current levels, except for a greater likelihood of mothers joining their children in expressing positive affect. Treatment history among these mothers may explain this finding.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Prospective study of depressive symptoms and incident cardiovascular diseases in people with type 2 diabetes

Xinming Xu, Chengwu Feng, Han Han, Tongtong Li, Nan Wang, Qishan Yang, Yi Guo, Xinyi Gan, Xiaohua Liu, Liang Sun, Alexandru Dregan, Geng Zong, Xiang Gao

Summary: Depressive symptoms in individuals with type 2 diabetes were found to be associated with a higher risk of cardiovascular diseases, with dose-response relationships observed between depressive symptoms and various cardiovascular outcomes. This suggests that screening for depressive symptoms could help predict cardiovascular disease outcomes in individuals with type 2 diabetes.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Review Clinical Neurology

Staying connected: An umbrella review of meta-analyses on the push-and-pull of social connection in depression

Luisa De Risio, Mauro Pettorruso, Rebecca Collevecchio, Barbara Collacchi, Marta Boffa, Mario Santorelli, Massimo Clerici, Giovanni Martinotti, Francesca Zoratto, Marta Borgi

Summary: Social factors play a crucial role in the development and severity of depression. Social support serves as a protective factor against depression, particularly in peripartum populations. However, stigma and discrimination have a weaker effect on depression in clinical populations and ethnic minorities.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

A machine learning algorithm-based model for predicting the risk of non-suicidal self-injury among adolescents in western China: A multicentre cross-sectional study

Yunling Zhong, Jinlong He, Jing Luo, Jiayu Zhao, Yu Cen, Yuqin Song, Yuhang Wu, Cen Lin, Lu Pan, Jiaming Luo

Summary: This study developed a predictive model using a machine learning algorithm to assess the risk of non-suicidal self-injurious behavior (NSSI) in Chinese adolescents more accurately. The results show that depression and anxiety are the top predictors of NSSI in adolescents. Additionally, factors such as gender, age, living arrangements, psychiatric consultation history, stress, depression, anxiety, tolerance, and emotional expression were found to be associated with the risk of NSSI in adolescents.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

The mental simulation of state/psychological stimuli in anxiety disorders: A 3T fMRI study

Barbara Tomasino, Eleonora Maggioni, Maria Chiara Piani, Carolina Bonivento, Serena D'Agostini, Matteo Balestrieri, Paolo Brambilla

Summary: Mental imagery plays an important role in cognitive and emotional processes. Individuals with anxiety disorders show faster and better processing of state/psychological stimuli. The left superior frontal gyrus is differentially activated during state/psychological imagery in anxious individuals.

JOURNAL OF AFFECTIVE DISORDERS (2024)