Clinical Neurology

Review Clinical Neurology

Facilitators of, barriers to, and preferences for e-mental health interventions for depression and anxiety in men: Metasynthesis and recommendations

Melissa J. Opozda, Melissa Oxlad, Deborah Turnbull, Himanshu Gupta, James A. Smith, Samuel Ziesing, Murray E. Nankivell, Gary Wittert

Summary: Little is known about men's use of online mental health interventions. This study aims to synthesize qualitative literature on men's preferences, attitudes, and experiences of using such interventions and provides recommendations based on the findings.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Letter Clinical Neurology

Mid-pregnancy sleep disorders and perinatal depression

Hui-Chin Chang, Shuo-Yan Gau

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Identification of central symptoms of children depression and development of two short version of Children's Depression Inventory: Based on network analysis and machine learning

Chao Zhang, Baojuan Ye, Zhifang Guo

Summary: The central symptoms of depression in Chinese rural children were identified as sadness, self-hatred, loneliness, and self-deprecation through network analysis. The developed CDI-10-N and CDI-SC showed high AUC values, demonstrating their effectiveness in screening depression symptoms.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Endometriosis, chronic pain, anxiety, and depression: A retrospective study among 12 million women

Hormoz Nassiri Kigloo, Rayan Itani, Tina Montreuil, Ido Feferkorn, Jason Raina, Togas Tulandi, Fady Mansour, Srinivasan Krishnamurthy, Eva Suarthana

Summary: This study, based on a large database, found potential associations between endometriosis and chronic pain with anxiety and depression. It suggests that clinicians should provide proper medical management for endometriosis-related pain and offer counseling for anxiety and depression.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Review Clinical Neurology

The association between trichotillomania symptoms and emotion regulation difficulties: A systematic review and meta-analysis

Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford

Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Patterns in suicide by marital status in Hong Kong, 2002-2020: Is marriage still a protective factor against suicide?

Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip

Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Escitalopram population pharmacokinetics and remedial strategies based on CYP2C19 phenotype

Xin Liu, Gehang Ju, Xinyi Huang, Wenyu Yang, Lulu Chen, Chao Li, Qingfeng He, Nuo Xu, Xiao Zhu, Dongsheng Ouyang

Summary: This study aimed to develop a popPK model characterizing the disposition of SCIT in the Chinese population and proposed remedial strategies for non-adherence scenarios. Significant covariates impacting SCIT exposure were identified, and recommendations for dosage adjustments in different scenarios were provided based on CYP2C19 phenotypes. The study highlighted the importance of personalized medication based on patient characteristics and the utilization of popPK repository for precision dosing.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

The mediating role of childhood maltreatment in the association between residence migration and adolescent depression

Wancheng Zheng, Lulu Wen, Yunjian Huang, Liyuan Huang, Chuming Yan, Jianghe Chen, Miao Qu

Summary: This study reveals that residence migration may contribute to adolescent depression, and childhood maltreatment may largely mediate this process. Reducing childhood maltreatment can effectively improve the depressive symptoms of migrant adolescents.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Letter Clinical Neurology

Response to Słupski & Słupska

Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Perinatal sleep disruption and postpartum psychosis in bipolar disorder: Findings from the UK BDRN Pregnancy Study

A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones

Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

The relationship between psychological pain and suicidality in patients with major depressive disorder: A meta-analysis

Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia

Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Understanding the longitudinal associations between e-cigarette use and general mental health, social dysfunction and anhedonia, depression and anxiety, and loss of confidence in a sample from the UK: A linear mixed effect examination

Weixi Kang, Antonio Malvaso

Summary: This study revealed longitudinal associations between e-cigarette initiation and adverse general and dimensions of mental health, except for depression and anxiety. Participants who started using e-cigarettes had worse mental health, social dysfunction and anhedonia, and loss of confidence compared to one year ago.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Global time trends of perceived loneliness among adolescents from 28 countries in Africa, Asia, and the Americas

Lee Smith, Guillermo F. Lopez Sanchez, Damiano Pizzol, Dong Keon Yon, Hans Oh, Karel Kostev, Julia Gawronska, Masoud Rahmati, Laurie Butler, Yvonne Barnett, Graham Ball, Jae Il Shin, Ai Koyanagi

Summary: This study aimed to investigate the temporal trends of perceived loneliness among school-going adolescents aged 12-15 years from 28 countries in Africa, Asia, and the Americas. The results showed significant increasing and decreasing trends of perceived loneliness among different countries. Egypt and Samoa exhibited the most drastic changes. Stable trends with high prevalence were also common.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Comparing a new multimorbidity index with other multimorbidity measures for predicting disability trajectories

Hui-Wen Xu, Hui Liu, Yan Luo, Kaipeng Wang, My Ngoc To, Yu-Ming Chen, He-Xuan Su, Zhou Yang, Yong-Hua Hu, Beibei Xu

Summary: In this study, a multimorbidity index was developed and found to be an effective measurement in predicting disability trajectories among middle-aged and older community-dwelling Chinese adults. The condition count was also suggested as a simple and superior measure for predicting disability trajectories.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Association between serum omega-3 PUFAs levels and cognitive impairment in never medically treated first-episode patients with geriatric depression: A cross-sectional study

Jing Gao, Huiyu Fan, Xiaohong Wang, Yangyinglin Cheng, Jingjing Hao, Siqi Han, Suping Wu

Summary: The study revealed that elderly patients with geriatric depression and cognitive impairment (CI) had higher serum levels of TC, LDL-C, and inflammatory markers IL-6, TNF-alpha, and hs-CRP, but lower levels of omega-3 PUFAs EPA, DHA, and AA. Linear regression analysis showed significant associations between EPA, DHA, TNF-alpha, hs-CRP levels and the occurrence and severity of CI among these patients.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Identification of the shared molecular mechanisms between major depressive disorder and COVID-19 from postmortem brain transcriptome analysis

Qishuai Zhuang, Rongqing Zhang, Xiaobing Li, Dapeng Ma, Yue Wang

Summary: This study investigates the molecular mechanisms underlying the interaction between major depressive disorder (MDD) and COVID-19, and explores diagnostic biomarkers and potential therapeutic drugs. It identifies common key genes involved in both COVID-19 and MDD, and selects four key genes based on clinical relevance. A multi-gene prediction model shows good diagnostic efficiency for COVID-19 and MDD. The study also identifies specific biological functions and pathways associated with key genes, and predicts potential therapeutic drugs targeting these genes.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

The correlation between mobile phone addiction and procrastination in students: A meta-analysis

Xiang Zhou, Fang Yang, Yan Chen, Yourong Gao

Summary: There is a significant positive correlation between mobile phone addiction and procrastination in students. This correlation is moderated by education level, sex, culture, and measurement tools of mobile phone addiction. The year of publication and measurement tools of procrastination do not moderate the correlation.

JOURNAL OF AFFECTIVE DISORDERS (2024)