Article
Chemistry, Organic
Nilesh Raghunath Khedkar, Alex Joseph, Milind Sindkhedkar
Summary: In this study, a new library of 3-(2-(pyrimidin-5-yl)thiazol-4-yl)-1,2,4-oxadiazole compounds was designed and synthesized as potential anticancer agents using in silico fragment-based drug design. The compounds were tested for their anticancer activity in vitro, and one compound exhibited excellent activity against multiple cancer cell lines.
SYNTHETIC COMMUNICATIONS
(2024)
Review
Chemistry, Organic
Ranjana Aggarwal, Swati Sharma
Summary: This review article mainly focuses on the synthesis of 3(5)-trifluoromethylpyrazoles via condensation reaction of trifluoromethyl-beta-diketones with hydrazines. It emphasizes the importance of fluorine-containing compounds and pyrazoles in the field of biology. The literature reported condensation reactions of trifluoromethyl-beta-diketones with hydrazines are covered.
SYNTHETIC COMMUNICATIONS
(2024)
Article
Chemistry, Organic
F. M. Alshareef, Sami A. Al-Harbi, Esam S. Allehyani, Omeima Abdullah, Magdy A. Ibrahim
Summary: This study aimed to construct a novel category of linear annulated chromeno[3',2':5,6]pyrido[2,3-d][1,3]thiazolo[3,2-a]pyrimidines. The chemical reactivity of the synthesized compounds was investigated, and they showed significant antimicrobial activity against various strains.
SYNTHETIC COMMUNICATIONS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ziteng Yang, Ruixuan Ni, Yang Yang, Jie Qi, Xingyu Lin, Yong Zhang, Li Wang, Yuanpeng Wu, Xiaojiang Li, Hongsheng Lu
Summary: In this study, a carboxymethyl cellulose-based supramolecular hydrogel with thermo-responsive gel-sol transition was prepared. The hydrogel showed tunable mechanical properties and good self-recovery. It quickly underwent a gel-sol transition upon thermal stimulus and exhibited pressure resistance and flame retardancy. Flushing the residual hydrogel with hot water effectively cleared the simulated pipeline. The supramolecular hydrogel has significant applications in the safe execution of hot work on pipelines.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Mengzhen Han, Wenzhi Lei, Jingjing Liang, Hongcai Li, Mengxin Hou, Zhenpeng Gao
Summary: Oral probiotic therapy is a safe and convenient method for treating various diseases. However, only a few probiotics can survive in the acidic and bile salt conditions of the gastrointestinal tract and have a nutritional effect on the host. Encapsulation technology and functional polysaccharides offer new approaches to improve the therapeutic efficacy of probiotics.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Jie Hou, Hua-Neng Xu
Summary: CD-based emulsions exhibit complex instability behaviors and the dispersion states of emulsion droplets are sensitive to the evolving morphologies of interfacial microcrystals. The ejection of ICs microcrystals from droplet surfaces provides a simple method to detect droplet-droplet interactions and phase transitions in CD-based emulsions.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xiaoping Zhao, Qin Wang, Ning Wang, Ge Zhu, Jingzhi Ma, Ning Lin
Summary: Cellulose nanocrystals (CNCs) show great potential in cancer treatment due to their biocompatibility and the ability to modify them with proteins and fluorescent molecules. Immobilizing CNCs with GAPDH and FITC creates the compound FCNC-G, which inhibits cancer cell proliferation and affects mitochondrial function. Loading FCNC-G with doxorubicin (DOX) further enhances its therapeutic potential.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yi Yang, Qingxi Ren, Zhilei Zhou, Xiong Li, Dongliang Ren, Zhongwei Ji, Jian Mao
Summary: HJPS1-2, a polysaccharide component in Huangjiu, has been found to have significant hepatoprotective effects, improving ethanol-induced hepatic dysfunction and steatosis. It also ameliorates gut microbiota dysbiosis and enhances intestinal barrier function, leading to reduced release of hepatic inflammatory cytokines and alleviation of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Organic
Jisna Jose, Thomas Mathew
Summary: 2-Cyclopentenone and its derivatives are highly esteemed synthetic intermediates with exceptional utility in organic synthesis. They are favored structural motifs in numerous pharmaceutical drugs and natural products, highlighting their significance. The review discusses the various methods used to synthesize cyclopentenones from 2016 to 2023.
Article
Chemistry, Applied
Prabu Satria Sejati, Firmin Obounou Akong, Frederic Fradet, Philippe Gerardin
Summary: This study investigates the role of different wood components in esterification and their effects on wood thermo-plasticization. Cellulose is found to play a significant role in wood plasticization, while hemicelluloses also have an effect. Acylated lignin improves the hydrophobic properties of the materials.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Mihai Brebu, Raluca Petronela Dumitriu, Daniela Pamfil, Elena Butnaru, Elena Stoleru
Summary: Chitosan-gelatin cryogels with good loading capacity of hydrophobic compounds were obtained through UV-induced crosslinking. These cryogels showed increased network stability, enhanced elastic behavior, higher structural strength, and self-healing capacity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Yinyi Fu, Haixin Jiao, Jianzhong Sun, Charles Obinwanne Okoye, Hongxing Zhang, Yan Li, Xuechu Lu, Qianqian Wang, Jun Liu
Summary: Macroalgae polysaccharides (MPs) are valuable bioactive compounds with diverse structures. Understanding the structure-activity relationships is crucial for developing effective biomedical applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Minhu Huang, Seunghyeon Lee, Il-Young Jo, Hyunbeen Park, Bong Sup Shim, Myung-Han Yoon
Summary: This study investigated the fabrication process and properties of fiber-type organic electrochemical transistors (OECTs). By utilizing composite fibers of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) and TEMPO-oxidized cellulose nanofiber (CNF), the mechanical strength of the fibers was significantly improved, leading to higher carrier mobility. These findings suggest great potential for eco-friendly wearable/textile electronics.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qi Xin, Qingliang Wang, Kaiwen Luo, Zhiwu Lei, Eming Hu, Hongqing Wang, Hongqiang Wang
Summary: Due to the development and use of nuclear energy, land-based uranium resources are becoming scarce. To address this shortage, a new carbon adsorbent was designed and synthesized for extracting uranium from seawater. The experimental results showed that the adsorbent had high adsorption capacity and selectivity for uranium, as well as good oil resistance and reusability.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Inorganic & Nuclear
Ahsan Nazir, Pengwei Huo, Ameena Tur Rasool
Summary: This review explores the potential of g-C3N4-based S-scheme heterojunctions in addressing environmental issues. It summarizes the mechanism and preparation techniques of S-scheme heterojunctions based on g-C3N4, and presents recent studies on their applications in pollutant removal, CO2 reduction, hydrogen production, and bacterial disinfection. The review concludes with an outlook on future challenges for g-C3N4-based S-scheme heterojunctions.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Applied
Xixi Zeng, Houyu Kang, Ling Chen, Xinyi Shen, Bo Zheng
Summary: The interaction between hot-extrusion treatment and starch-proanthocyanidins was found to enhance the nutritional properties of chestnut starch, including an increase in resistant starch content and enhanced alpha-amylase inhibitory activity, antioxidant activity, and antiglycation activity. Additionally, the treated starch increased the levels of short chain fatty acids, particularly propionate, and enriched beneficial intestinal bacteria. This study provides an approach to improve the nutritional functions of starch and offers guidance for improving the nutritional quality of chestnut starch-based foods.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Inorganic & Nuclear
Zahra Karimi Sangari, Hossein Naeimi
Summary: In this research, a nanostructured CoCuFe2O4 catalyst was prepared using a brief and useful synthetic strategy. This catalyst was used for synthesizing 1,2,4,5-tetrasubstituted imidazole derivatives under ultrasonic irradiation. The approach offers advantages such as high efficiency, short reaction times, simplicity of the reaction medium, accelerated reaction rates, and easier separation and purification of products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Organic
Fuying Zhu, Yamei Lin
Summary: In this study, a low-metal iron-supported catalyst (Fe20/NC-Mg) was reported for the efficient synthesis of quinoxaline compounds, using water as a solvent and without additional bases. The synergistic effect of FeNx site and Mg (OH)2 nanorods in the catalyst played a key role in achieving high yields (82-91%) in 16 examples. The gram-level synthesis and reusability of the catalysts after four cycles demonstrated its industrial application potential.
