Article
Chemistry, Multidisciplinary
Yu Han, Liyun Zhou, Chengyu Wang, Shangti Feng, Rong Ma, Jie-Ping Wan
Summary: Enaminones, versatile building blocks in organic synthesis, possess both nucleophilic enamine and electrophilic enone structures. Visible light-mediated reactions have emerged as a sustainable and useful synthetic strategy, and have been successfully applied to construct cyclic or acyclic compounds from enaminones. This review describes the recent advances in visible light-mediated chemical transformations of enaminones, providing detailed discussion on reaction mechanisms to guide readers. A summary on existing challenges and future outlook towards practical photocatalytic reactions of enaminones is also presented.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Mei Li, Yanyan Zhou, Jingya Li, Wenru Huang, Zhiwei Yao, Yuying Li, Ting Gao, Pengfei Yan, Hongfeng Li
Summary: Chiroptical switches based on circularly polarized luminescence (CPL) have shown promising applications in advanced information technologies. In this study, a pair of lanthanide coordination polymer enantiomers with light-regulated CPL property were designed and exhibited reversible photochromism, PL, and CPL responses. The CPL photo-switching property of the complexes in solid hybrid film was maintained and displayed enhanced CPL emission.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yunlei Zhang, Yiran Liu, Wen Guan, Mengxue Cao, Yao Chen, Pengwei Huo
Summary: The unique properties of metal oxide surfaces, crystal surfaces, and defects are crucial for biomass upgrading reactions. This study designed a hierarchical porous bowl-shaped ZrO2 (HB-ZrO2) support and loaded it with AuPd bimetal to investigate the effects of surface chemistry, oxygen defects, bimetal interaction, and metal-support interaction on catalytic performance. The Au2Pd1/HB-ZrO2 catalyst showed excellent performance in the selective oxidation of HMF to FDCA, achieving high yield and productivity.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Jin Wang, Qingqing Zhang, Yanchen Li, Xiaoyan Pan, Yuanyuan Shan, Jie Zhang
Summary: Remodeling tumor microenvironment is an effective strategy to enhance the effects of chemotherapy, photodynamic therapy, and immunotherapy. A novel therapeutic nanoparticle has been developed to improve the tumor microenvironment and induce antitumor effects by combining a vascular normalization inducer, a GSH depleting agent, and an activated fluorophore.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Xin Wu, Xinmei Chen, Xinyu Wang, Haisheng He, Jianming Chen, Wei Wu
Summary: Paclitaxel-loaded liposomes hold potential for the treatment of breast carcinoma and other cancers. By conjugating paclitaxel with lipids of different chain lengths, the drug release and enzymatic conversion rates can be controlled, affecting the pharmacokinetics, tumor accumulation, and anti-tumor efficacy of liposomal paclitaxel.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yuanyuan Liao, Yuting Liang, Yurou Huang, Xiaoyan Zeng, Tian He, Jun Yin
Summary: Cyanine dyes, specifically heptamethine cyanine (Cy7) dyes, have been widely used in biological imaging due to their excellent fluorescence properties and biological function. They are considered effective fluorescent tools in living organisms because of their biocompatibility and low background interference. Recently, there has been significant progress in bioorthogonal reactions performed in living cells and tissues. The use of cyanine dyes in near-infrared fluorescent labeling techniques has attracted considerable attention. This review summarizes the recent applications of Cy7-type dyes in bioorthogonal imaging, including labeling strategy and bioimaging applications. It aims to provide assistance for the study of near-infrared bioorthogonal reactions in vivo.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhukang Guo, Baijiang Jin, Yile Fang, Lian Jin, Song Li, Yan Deng, Zhu Chen, Hui Chen, Yuanying Zhang, Rabia Usman, Nongyue He
Summary: This study isolated primary cells that can be stably passaged from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice and used an autonomously developed automated screening instrument for efficient nucleic acid aptamer screening. The obtained aptamers were affinity verified at the cellular level. The study also investigated the impact of cell growth environment difference on the recognition ability of aptamers and confirmed the targeting ability and drug loading ability of the aptamer.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Tangxin Xiao, Xiuxiu Li, Liangliang Zhang, Kai Diao, Zheng-Yi Li, Xiao-Qiang Sun, Leyong Wang
Summary: This study presents the construction of a supramolecular light harvesting system based on sequential energy transfer. The system demonstrates tunable fluorescence emission through self-assembly of polymers into nanoparticles, achieving efficient two-step light harvesting.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Qi Fu, Zhongming Lian, Mengya Niu, Yaru Huang, Yanqiu Ai, Long He, Dandan Zhang, Cuixia Zheng, Jian-Jun Yang, Lei Wang, Dandan Tian
Summary: In this study, a near-infrared light-activated nano-therapeutic system was constructed for the concurrent treatment of breast cancer bone metastasis and cancer-induced bone pain (CIBP). The designed nanoplatform effectively destroys tumor cells and reduces CIBP in both in vitro and in vivo experiments. Additionally, it inhibits osteoclast activation, promotes osteoblast differentiation, and accelerates bone repair.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Oleg Egorov, Michael Rey, Dominika Viglaska, Andrei V. Nikitin
Summary: In this work, the rovibrational energy levels of four isotopologues of methylene were calculated using a new accurate ab initio potential energy surface. The accuracy of the calculations was improved by considering scalar relativistic effects, DBOC, and high-order electronic correlations. For the first time, all available experimental rovibrational transitions were reproduced with high accuracy, without any empirical corrections.
JOURNAL OF COMPUTATIONAL CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Michal Novotny, Matus Dubecky, Frantisek Karlicky
Summary: This paper investigates the accuracy of different DFT-based computational approaches in calculating the equilibrium lattice constants and exfoliation energy of hexagonal boron nitride (h-BN). The results are compared with experiments and reference QMC calculations to evaluate the accuracy of these computational methods.
JOURNAL OF COMPUTATIONAL CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Vasilii Korotenko, Hendrik Zipse
Summary: The stability of various radicals and molecules has been studied using different theoretical methods, and good correlations between theoretical calculations and experimental results have been found. The effects of hydrogen bonding interactions on the stability of oxygen-centered radicals have also been investigated.
JOURNAL OF COMPUTATIONAL CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Jason Malenfant, Lucille Kuster, Yohann Gagne, Kouassi Signo, Maxime Denis, Sylvain Canesi, Mathieu Frenette
Summary: Raman microscopy can reveal compound-specific vibrational fingerprints without sample preparation. The combination of efficient theoretical calculations and a user-friendly software can accurately predict peak positions and provide match scores to assist with structure determination.
