Chemistry, Analytical

Article Biophysics

CRISPR/Cas-powered nanobiosensors for diagnostics

Quynh Anh Phan, Linh B. Truong, David Medina-Cruz, Can Dincer, Ebrahim Mostafavi

Summary: CRISPR-Dx offers broad enhancements compared to traditional nanobiosensors by utilizing the trans-cleavage activity of the CRISPR/Cas systems. However, the current singlestranded DNA/RNA reporters of CRISPR-Dx have poor stability and limited sensitivity. Research is shifting towards using the trans-cleavage activity of CRISPR/Cas effectors on metal nanoparticles to develop novel nanobiosensors with high accuracy, sensitivity, selectivity, and versatility.

BIOSENSORS & BIOELECTRONICS (2022)

Article Chemistry, Analytical

Capacitive Aptasensor Coupled with Microfluidic Enrichment for Real-Time Detection of Trace SARS-CoV-2 Nucleocapsid Protein

Haochen Qi, Zhiwen Hu, Zhongliang Yang, Jian Zhang, Jie Jayne Wu, Cheng Cheng, Chunchang Wang, Lei Zheng

Summary: A fast-responding and quantitative capacitive aptasensor has been developed for ultratrace nucleocapsid protein detection. The sensor has a quick response time, high sensitivity, and high selectivity, meeting the real-time detection demand.

ANALYTICAL CHEMISTRY (2022)

Review Chemistry, Analytical

Study and Investigation on 5G Technology: A Systematic Review

Ramraj Dangi, Praveen Lalwani, Gaurav Choudhary, Ilsun You, Giovanni Pau

Summary: This paper presents the characteristics and advantages of 5G technology as the latest generation of mobile networks, highlighting how businesses can utilize the opportunities brought by 5G.

SENSORS (2022)

Article Chemistry, Analytical

MSFT-YOLO: Improved YOLOv5 Based on Transformer for Detecting Defects of Steel Surface

Zexuan Guo, Chensheng Wang, Guang Yang, Zeyuan Huang, Guo Li

Summary: With the development of artificial intelligence technology and the popularity of intelligent production projects, intelligent inspection systems have become a hot topic in the industrial field. This paper introduces the improved MSFT-YOLO model for object detection in the industry, which addresses challenges such as background interference and scale changes. The model achieves real-time detection and shows higher detection accuracy compared to baseline models, offering advantages and improvements.

SENSORS (2022)

Article Chemistry, Analytical

Tunable Diode Laser Absorption Spectroscopy Based Temperature Measurement with a Single Diode Laser Near 1.4 μm

Xiaonan Liu, Yufei Ma

Summary: This paper demonstrates a temperature measurement method based on the tunable diode laser absorption spectroscopy (TDLAS) technique using a single diode laser. The TDLAS system showed advantages such as immunity to laser wavelength shift, simple system structure, reduced cost, and increased system robustness. The system was tested on a McKenna flat flame burner and a scramjet model engine, and exhibited excellent dynamic range and fast response.

SENSORS (2022)

Review Chemistry, Analytical

Federated Learning in Edge Computing: A Systematic Survey

Haftay Gebreslasie Abreha, Mohammad Hayajneh, Mohamed Adel Serhani

Summary: Edge Computing is a new architecture that extends Cloud Computing services closer to data sources. When combined with Deep Learning, it becomes a promising technology widely used in various applications. However, the traditional DL architectures with EC enabled often face practical challenges due to high bandwidth requirements, legal issues, and privacy vulnerabilities. Federated Learning has emerged as a potential solution to address these challenges by enabling collaborative learning and model optimization while ensuring data localization. This paper provides a systematic survey of the implementation of Federated Learning in Edge Computing environments, including protocols, architectures, frameworks, and hardware requirements. It also discusses applications, challenges, related solutions, and presents case studies and potential directions for future research.

SENSORS (2022)

Article Chemistry, Analytical

Green synthesis of TiO2 nanoparticles using lemon peel extract: their optical and photocatalytic properties

Ghulam Nabi, Qurat-Ul-Ain, M. Bilal Tahir, Khalid Nadeem Riaz, Tahir Iqbal, Muhammad Rafique, Sajad Hussain, Waseem Raza, Imran Aslam, Muhammad Rizwan

Summary: This study reports the first synthesis of TiO2 nanoparticles using lemon peel extract through green synthesis method. The synthesized particles showed high photocatalytic activity, which was more efficient compared to commercial TiO2 particles.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY (2022)

Article Chemistry, Analytical

Non-free Fe dominated PMS activation for enhancing electro-Fenton efficiency in neutral wastewater

Ying Wang, Tong Sun, Li Tong, Yidi Gao, Hong Zhang, Yuxin Zhang, Zhihua Wang, Suiyi Zhu

Summary: The high performance of non-free Fe in the electro-Fenton system was observed using rod-shaped erdite for PMS activation in an electric field. Erdite, synthesized from waste waterwork sludge, had a one-dimensional structure of (FeS2)nn- group and could release Fe/S-bearing colloid in neutral water. In the electric field, the erdite hydrolysis was inhibited but continued by adding PMS, generating free radicals of .OH and SO4-. The presence of erdite/PMS in the electric field significantly enhanced the removal efficiency of p-nitrophenol.

JOURNAL OF ELECTROANALYTICAL CHEMISTRY (2023)

Article Biophysics

Metal-organic frameworks based hybrid nanocomposites as state-of-the-art analytical tools for electrochemical sensing applications

Tahir Rasheed, Komal Rizwan

Summary: This paper systematically summarizes recent breakthroughs in MOFs and their derivatives in enhanced electrochemical sensing applications. The overview part provides insights into the future prospects and directions of MOFs and their derivatives, aiming to overcome present limitations.

BIOSENSORS & BIOELECTRONICS (2022)

Review Chemistry, Analytical

Electrochemical Impedance Spectroscopy-A Tutorial

Alexandros Ch. Lazanas, Mamas I. Prodromidis

Summary: This tutorial provides the theoretical background, principles, and applications of Electrochemical Impedance Spectroscopy (EIS) in various research and technological sectors. It covers topics such as sinusoidal signals, complex numbers, phasor notation, transfer functions, impedance in electrical circuits, EIS principles, validation of experimental data, simulation to equivalent electrical circuits, and practical considerations. The tutorial includes interactive excel files showing Nyquist and Bode plots of model circuits. It is intended to be a valuable educational tool for graduate students and senior researchers involved in EIS, as well as an aid for EIS instructors.

ACS MEASUREMENT SCIENCE AU (2023)

Article Chemistry, Analytical

Electrochemical neuron-specific enolase (NSE) immunosensor based on CoFe2O4@Ag nanocomposite and AuNPs@MoS2/rGO

Ceren Karaman, Omer Saltuk Bolukbasi, Bahar Bankoglu Yola, Onur Karaman, Necip Atar, Mehmet Lutfi Yola

Summary: In this study, an electrochemical NSE immunosensor based on AuNPs@MoS2/rGO electrode platform and CoFe2O4@Ag nanocomposite as the signal amplification was developed, which can be successfully utilized in the early diagnosis for lung cancer.

ANALYTICA CHIMICA ACTA (2022)

Article Biophysics

Frontier and hot topics in electrochemiluminescence sensing technology based on CiteSpace bibliometric analysis

Xiancheng Liu, Shuang Zhao, Lili Tan, Yu Tan, Yi Wang, Zhiyi Ye, Changjun Hou, Yan Xu, Shan Liu, Guixue Wang

Summary: This review article provides a comprehensive retrospective analysis of the development, research hotspots, and future trends of electrochemiluminescence (ECL) technology in the past 20 years through quantitative analysis and visual review. It also includes a detailed review and analysis of selected highly cited articles. The article particularly emphasizes the development needs of ECL technology in terms of improving sensor performance, developing materials with excellent ECL performance, innovating and cooperating with other devices, and developing high-speed and high-throughput sensors.

BIOSENSORS & BIOELECTRONICS (2022)

Article Biophysics

Simultaneous detection of dual biomarkers using hierarchical MoS2 nanostructuring and nano-signal amplification-based electrochemical aptasensor toward accurate diagnosis of prostate cancer

Ruohong Yan, Na Lu, Suping Han, Zhanglu Lu, Yang Xiao, Zhihang Zhao, Min Zhang

Summary: The study introduces an electrochemical aptasensor using MoS2 nanostructuring and SiO2 nano-signal amplification for simultaneous detection of PSA and sarcosine in prostate cancer. This approach allows for ultrasensitive detection, differentiation of cancer patients from healthy individuals, and provides a single-step analysis for accurate diagnosis and early detection of cancer in clinical settings.

BIOSENSORS & BIOELECTRONICS (2022)

Article Chemistry, Analytical

Gold-loaded tellurium nanobelts gas sensor for ppt-level NO2 detection at room temperature

Zhen Yuan, Qiuni Zhao, Chunyan Xie, Junge Liang, Xiaohui Duan, Zaihua Duan, Shaorong Li, Yadong Jiang, Huiling Tai

Summary: In this study, gold-loaded tellurium nanobelts were synthesized through a hydrothermal process, and the resulting Au@Te sensor demonstrated rapid response, high sensitivity, good repeatability, and selectivity for the detection of NO2. The long-term stability of the sensor was also evaluated, with stable response observed over a period of 28 days.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Article Biophysics

Towards hospital-on-chip supported by 2D MXenes-based 5th generation intelligent biosensors

Vishal Chaudhary, Virat Khanna, Hafiz Taimoor Ahmed Awan, Kamaljit Singh, Mohammad Khalid, Yogendra Kumar Mishra, Shekhar Bhansali, Chen-Zhong Li, Ajeet Kaushik

Summary: This article introduces the fifth-generation portable intelligent and multifunctional biosensors embedded on a single chip, which are used for current public health emergencies. The article discusses in detail the advancements in MXene fabrication, physicochemical properties, and the application prospects of MXene-based biosensors in the medical field, as well as the sustainability and challenges associated with these technologies.

BIOSENSORS & BIOELECTRONICS (2023)

Article Chemistry, Analytical

Triple-Band Surface Plasmon Resonance Metamaterial Absorber Based on Open-Ended Prohibited Sign Type Monolayer Graphene

Runing Lai, Pengcheng Shi, Zao Yi, Hailiang Li, Yougen Yi

Summary: This paper introduces a novel metamaterial absorber based on surface plasmon resonance (SPR) that has triple-mode perfect absorption, polarization independence, incident angle insensitivity, tunability, high sensitivity, and a high figure of merit (FOM). The structure of the absorber consists of a graphene array, SiO2 layer, and a gold mirror. The absorber achieves perfect absorption at frequencies of 4.04 THz, 6.76 THz, and 9.40 THz, with absorption peaks of 99.404%, 99.353%, and 99.146%, respectively. It also demonstrates maximum sensitivities in refractive index sensing and has potential applications in photodetectors, optoelectronic devices, and chemical sensors.

MICROMACHINES (2023)

Article Biophysics

Fabricated Metal-Organic Frameworks (MOFs) as luminescent and electrochemical biosensors for cancer biomarkers detection

Brij Mohan, Sandeep Kumar, Hui Xi, Shixuan Ma, Zhiyu Tao, Tiantian Xing, Hengzhi You, Yang Zhang, Peng Ren

Summary: The study focuses on the application of sensors made of porous metal-organic frameworks (MOFs) in cancer biomarker detection, analyzing factors such as fabrication strategies and structural properties that influence sensing performance, and proposes an innovative technique for detecting cancer biomarkers using luminescence and electrochemical sensors.

BIOSENSORS & BIOELECTRONICS (2022)

Review Chemistry, Analytical

Molecularly imprinted polymers based materials and their applications in chromatographic and electrophoretic separations

Zhihua Song, Jinhua Li, Wenhui Lu, Bowei Li, Gangqiang Yang, Yi Bi, Maryam Arabi, Xiaoyan Wang, Jiping Ma, Lingxin Chen

Summary: Molecularly imprinted polymers (MIPs) possess selective recognition towards template molecules and their analogues, and can be easily obtained in various formats and traits through different preparation methods. It is an influential and extensively developed strategy to enhance the recognition selectivity and detection sensitivity of chromatographic techniques by using MIPs-based stationary phases (SPs).

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2022)

Article Biophysics

Exploiting the orthogonal CRISPR-Cas12a/Cas13a trans-cleavage for dual-gene virus detection using a handheld device

Tian Tian, Zhiqiang Qiu, Yongzhong Jiang, Debin Zhu, Xiaoming Zhou

Summary: This study introduces a highly efficient dual-gene detection technique based on the orthogonal DNA/RNA collateral cleavage mechanism of the Cas12a/Cas13a system. The technique allows simultaneous detection of multiple amplified products and can be implemented on a portable device for accurate infectious disease screening in resource-limited settings.

BIOSENSORS & BIOELECTRONICS (2022)

Article Chemistry, Analytical

Ni-Co-P hollow nanobricks enabled humidity sensor for respiratory analysis and human-machine interfacing

Chunxu Chen, Mingjiao Jiang, Xiaolan Luo, Huiling Tai, Yadong Jiang, Min Yang, Guangzhong Xie, Yuanjie Su

Summary: This work presents a new metal phosphide nanomaterial for energy storage and catalysis, replacing chemical sensors. The material exhibits high sensitivity, low hysteresis, and good repeatability in a wide range of humidity. By adjusting the composition, the humidity sensing performance can be efficiently modulated, showing great potential in respiratory analysis and non-contact human-machine interfacing. This research opens up new possibilities for developing high-performance wearable sensing devices.

SENSORS AND ACTUATORS B-CHEMICAL (2022)