Review
Cardiac & Cardiovascular Systems
Susanna Hamsley, Issa Pour-Ghaz, Deya Alkhatib, Hallie Norman, Rachana Kombathula, Mannu Nayyar, David A. Mccaslin, Rami N. Khouzam, Neeraja Yedlapati, Ajay Dalal
Summary: The coronavirus pandemic has introduced new forms of disease and unique presentations of existing diseases. Through ongoing research, we are uncovering the long-term effects of the pandemic and discovering previously unknown features.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Julia Leao Batista Simoesa, Georgia de Carvalho Bragaa, Tamires Hillesheim Mittelmanna, Margarete Dulce Bagatinib
Summary: Studies show that the COVID-19 pandemic has caused serious psychological problems and physical stress, resulting in cardiac dysfunction known as Takotsubo Syndrome. The purinergic system plays a crucial role in this pathological process, indicating the need for further research on the role of purines.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Ishan M. Tungar, Murali Mohan Rama Krishna Reddy, Sofia M. Flores, Prakriti Pokhrel, Abdulgafar Dare Ibrahim
Summary: Lifestyle factors such as stress levels, caffeine, drugs, alcohol, nicotine, sleep, and physical exercise can increase the occurrence of premature ventricular contractions (PVC). These factors can cause heightened cardiac stimulation or disturb electrical pathways, leading to PVC. Obesity, insomnia, and increased stress levels are also associated with a higher risk of PVC.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
S. Hammad Jafri, Pavel Hushcha, Pranav Dorbala, Gisele Bousquet, Christine Lutfy, Lauren Mellett, Lindsay Sonis, Ron Blankstein, Christopher Cannon, Jorge Plutzky, Donna Polk, Hicham Skali
Summary: Despite the established benefits of optimal medical therapy (OMT) in patients with coronary artery disease (CAD) and/or heart failure (HF), it is still underused. Cardiac rehabilitation (CR) programs may promote the use of OMT, especially in CAD patients. However, the use of OMT remains low in HF patients enrolled in CR.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Baolu Yang, Leyi Gao, Zhaohui Tong
Summary: The use of sedative and analgesic medications during non-invasive ventilation can reduce the risk of tracheal intubation and delirium in patients with acute respiratory failure. Among the different medications, dexmedetomidine showed better clinical outcomes, especially when closely monitoring the patients' vital signs.
Review
Cardiac & Cardiovascular Systems
Ross Arena, Nicolaas P. Pronk, Colin Woodard
Summary: This commentary examines the relationship between physical inactivity, obesity, and election results, socioeconomic factors, race, and regional culture in the United States. The study found that counties where the Democratic candidate received more votes had lower levels of physical inactivity and obesity, higher median national incomes, a higher proportion of Black population, and a higher percentage of people with higher education. However, there were variations in this relationship across different cultural regions in the United States.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Eriadina Alves Lima, Gezabell Rodrigues, Beatriz Carneiro Mota, Shamyr Sulyvan Castro, Rafael Barreto Mesquita, Camila Ferreira Leite
Summary: This study investigated the components of the International Classification of Functioning, Disability and Health (ICF) reflected in the assessment instruments used in cardiac rehabilitation for individuals with heart failure (HF). The results showed that body function was the most frequently detected component, but none of the instruments covered all aspects of the ICF. The Minnesota Living with Heart Failure Questionnaire (MLHFQ) demonstrated the most comprehensive coverage of ICF components.
Review
Cardiac & Cardiovascular Systems
Maryam Mahjoubin-Tehran, Vasily N. Sukhorukov, Tannaz Jmaialahmadi, Amirhossein Sahebkar
Summary: In this study, we used microarray profiles obtained from the GEO database to identify key genes associated with primary metabolic processes. Through gene ontology analysis and protein-protein interaction analysis, we found 11 differentially expressed genes, including 8 genes involved in these processes, with RORA, NR1D2, PIK3R1, CKAP4, and GZMK identified as central players in the network.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Waqas Ullah, Abdul-Rahman M. Suleiman, Heba Osman, Sairamya Bodempudi, Hamza Zahid Ullah Muhammadzai, Salman Zahid, Mohamed Zghouzi, Yasar Sattar, Salim S. Virani, David L. Fischman, M. Chadi Alraies
Summary: This study analyzed data from the Nationwide Readmissions Database and found that patients undergoing transcatheter aortic valve implantation (TAVI) for aortic insufficiency had higher rates of in-hospital clinical events, mortality, major bleeding, and valvular complications compared to those undergoing TAVI for aortic stenosis. However, there were no significant differences in these complications at 30-day and 180-day follow-up.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Dejina Thapa, Sek Ying Chair, Mei Sin Chong, Rishi Ram Poudel, Tenaw Gualau Melesse, Kai Chow Choi, Hon Lon Tam
Summary: The ventilator bundle has been found to effectively reduce the incidence of ventilator-associated pneumonia and improve related outcomes. However, caution should be exercised in interpreting these findings due to the low-to-moderate certainty of evidence and high heterogeneity.
Review
Cardiac & Cardiovascular Systems
Muneeb Ullah, Ayisha Bibi, Abdul Wahab, Shah Hamayun, Mahboob Ur Rehman, Shahid Ullah Khan, Uzma Azeem Awan, Noor-ul-ain Riaz, Muhammad Naeem, Sumbul Saeed, Talib Hussain
Summary: 3D printing technology has brought innovation in the field of cardiovascular medicine, especially in the management of cardiovascular disease (CVD). It has revolutionized the design and fabrication of intravascular stents, providing tailored solutions for complex anatomies and individualized patient needs. The advantages of 3D-printed stents include improved biocompatibility, enhanced mechanical properties, and reduced risk of restenosis. However, there are regulatory considerations and challenges in implementing 3D-printed stents in clinical practice.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Akanimo Antia, Endurance Evbayeka, Ovie Okorare, Daniel Ubokudom, Oghenetejiri Gbegbaje, Emmanuel Daniel
Summary: Obesity is a significant factor contributing to the development of cardiovascular conditions, particularly atrial fibrillation. Mechanisms such as fat deposition and atrial remodeling play a role in the development of atrial fibrillation in obese patients. Strategies to prevent and manage obesity include lifestyle adjustments, dietary modifications, pharmacological treatments, and surgical interventions, with bariatric surgery showing promising outcomes in reducing the prevalence of atrial fibrillation in obese patients.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Muhammad Shahzeb Khan, Anousheh Awais Paracha, Jan Biegus, Rafael de la Espriella, Julio Nunez, Carlos G. Santos-Gallego, Dmitry Yaranov, Marat Fudim
Summary: The increase of preload in heart failure can lead to excessive intracardiac pressures. The reduction of preload can be achieved through pharmacological and nonpharmacological interventions, with nonpharmacological interventions aiming to reduce blood inflow or increase splanchnic vascular blood pooling.
HEART FAILURE CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Husam M. Salah, Claudia Baratto, Dmitry M. Yaranov, Karl-Philipp Rommel, Satyanarayana Achanta, Sergio Caravita, Vinay Kumar Reddy Vasanthu, Marat Fudim
HEART FAILURE CLINICS
(2024)
Review
Cardiac & Cardiovascular Systems
Ronald D. Bass, Joseph Phillips, Jorge Sanz Sanchez, Priti Shah, Stephen Sum, Ron Waksman, Hector M. Garcia-Garcia
Summary: NIRS-derived LCBI is an effective measurement for identifying vulnerable patients and plaques at risk of future adverse events. Patients with an elevated LCBI have higher odds of enduring a future adverse event.
HEART FAILURE CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Adam Bland, Eunice Chuah, William Meere, Thomas J. Ford
Summary: CMD is a challenging condition to manage due to its heterogenous pathophysiology, presentation, and response to therapy. Although awareness of CMD is improving, there is a lack of randomized trials for therapy. Invasive assessment of the coronary microcirculation can improve patient-centered outcomes. Beta-blockers are the cornerstone of therapy for CMD angina, and non-pharmacological interventions play a central role in management. Further research is needed to assess the impact of traditional and novel pharmacological therapies on symptoms and clinical events in different CMD endotypes.
HEART FAILURE CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Xiaoxi Yao, Zachi I. Attia, Emma M. Behnken, Melissa S. Hart, Shealeigh A. Inselman, Kayla C. Weber, Fan Li, Nikki H. Stricker, John L. Stricker, Paul A. Friedman, Peter A. Noseworthy
Summary: This study aims to explore whether Apple Watch, used as a long-term monitoring device, is effective in the early diagnosis of atrial fibrillation (AF) and the prevention of cognitive function decline in older adults. By using AI-ECG to screen high-risk patients and record electrocardiograms, the effectiveness of Apple Watch will be evaluated. If successful, this approach could have significant implications on how future clinical practice leverages consumer devices for early diagnosis and disease prevention.
AMERICAN HEART JOURNAL
(2024)
Article
Cardiac & Cardiovascular Systems
Liu Huang, Mengtao Song, Ling Wang, Qiran Zhang, Xiao Liu, Chunfeng Cai
Summary: This study examines the reliability and validity of the Chinese Interoceptive Awareness Questionnaire (C-IAQ) for Chinese cardiovascular disease (CVD) patients. The results indicate that the C-IAQ has favorable psychometric features and can be used to measure the interoceptive awareness of CVD patients.
Review
Cardiac & Cardiovascular Systems
Hamza Irfan
Summary: Obesity is a major risk factor for cardiovascular disease. Semaglutide, a GLP-1 receptor agonist initially used for weight loss and diabetes, has shown potential in preventing obesity-associated CVD by significantly reducing major adverse cardiovascular events (MACE) risk.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Anas Hashem, Amani Khalouf, Ankit Agrawal, Mohamad Salah Mohamad, Tarek Nayfeh, Anthony Kashou, Rody G. Bou Chaaya, Devesh Rai, Basil Verghese, Stephen H. Little, Andrew Goldsweig, Srihari Naidu, Sachin S. Goel
Summary: This study evaluated the feasibility, safety, and clinical outcomes of intracardiac echocardiography (ICE) guided mitral transcatheter edge-to-edge repair (mTEER) procedure. The results showed no significant differences in in-hospital mortality, complications, and hospital costs compared to transesophageal echocardiography (TEE) guided mTEER.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
