Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Anas Alsughayer, Abdulmajeed Alharbi, Momin Shah, Michelle Cherian, Rohit Vyas, Ragheb Assaly
Summary: This study investigates the relationship between myocardial bridging (MB) and hypertrophic cardiomyopathy (HCM) and their impact on percutaneous coronary intervention (PCI) outcomes. The findings indicate that HCM patients have a higher risk of post-PCI complications, including atrial fibrillation and acute kidney injury, while MB is associated with increased occurrences of acute heart failure and post-PCI bleeding.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Junsu Lee, Hyunmin Lee, Adham El Sherbini, Leili Baghaie, Fleur Leroy, Husam Abdel-Qadir, Myron R. Szewczuk, Mohammad El-Diasty
Summary: Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery and can increase the risk for adverse outcomes. Current literature suggests that miRNAs may play a role in predicting the development of atrial fibrillation after cardiac surgery, but more robust clinical data are needed to justify their use in routine clinical practice.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Jessica Hernandez-Duran, Laura Valentina Lopez-Gutierrez, Maria Isabel Palacio-Mejia, Luisa Aguilera, Lucrecia Burgos, Clara Ines Saldarriaga Giraldo
Summary: This article examines the current situation of heart failure in Latin American women and identifies the need for future research.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Salman Salehin, Wissam Harmouch, Maha Yaqub, Umer Khan, Anwar Merie, Shahran Salehin, Syed Mustajab Hasan, Wissam Khalife, Muhie Dean Sabayon, Khaled Chatila, Muhammad Raja
Summary: Heart failure is a significant global health issue with high mortality rates. While guideline-directed medical therapy and device-based therapies have improved outcomes, not all advanced heart failure patients benefit from these treatments. Cardiac contractility modulation is an innovative therapy that aims to improve functional outcomes and quality of life for these patients.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Guang-Gui Zeng, Qiong Lei, Wan-Li Jiang, Xing-Xing Zhang, Liluo Nie, Xianghao Gong, Kang Zheng
Summary: This research paper uses bibliometric analysis to examine the historical evolution, current areas of interest, and future development trends of ABCG1. It reveals that research on ABCG1 has remained active over the past two decades and has started to expand into other fields such as cancer research. This study provides insights into the research status and emerging trends of ABCG1, and offers potential areas of focus for future studies.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Lanlan Zhang, Yanmin Zhang, Jing Wang, Shengjun Ta, Jia Zhao, Lu Yao, Chao Han, Jiao Liu, Xueli Zhao, Jiarui Yuan, Ruoxuan Li, Bo Shan, Yue Wang, Yuze Qin, Bo Wang, Liwen Liu
Summary: This study analyzed the clinical characteristics of 1023 unrelated hypertrophic cardiomyopathy (HCM) patients carrying the MYH7-R143Q variant. It was found that patients carrying this variant were often diagnosed between the ages of 31-40, with moderate hypertrophy and fibrosis concentrated in the anterior and inferior septum, indicating a moderate risk of sudden cardiac death (SCD). Moreover, this variant exhibited different genetic characteristics, including incomplete penetrance of autosomal dominant inheritance and polygenic cumulative effect.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Jianjun Wu, Dawei Yang, Fan Yang
Summary: Cardiovascular diseases pose a significant global public health challenge, and emerging research highlights the correlation between sleep disorders and CVD. Sleep quality is closely related to cardiovascular disease risk, and exercise interventions play a crucial role in improving sleep quality and reducing the risk of CVD.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Wynne Widiarti, Chaq El Chaq Z. Multazam, Dinda S. Octaviana, Hendri Susilo, Mochamad Y. Alsagaff, Citrawati D. K. Wungu
Summary: Fluid therapy in the management of cardiogenic shock plays a crucial role but is still controversial. Studies have shown inconsistent results, involving different patient populations and underlying causes. The effectiveness of fluid therapy may vary depending on the type of cardiogenic shock.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Zixuan Ma, Yuanxin Zhou, Pengpu Li, Wenkai He, Mingyan Li
Summary: This study assesses the application of 4D flow CMR in MFS through a systematic review and meta-analysis. The findings indicate differences in various indicators between MFS patients and healthy subjects, providing insights into diagnosing cardiovascular diseases and predicting cardiovascular events in MFS patients.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Kashvi Gupta, Ioannis Mastoris, Andrew J. Sauer
HEART FAILURE CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Eric A. Shikatani, Tao Wang, Luke S. Dingwell, Colin White-Dzuro, Abdul Momen, Mansoor Husain
Summary: This study found that GDF5 deficiency can reduce the incidence of cardiac rupture after myocardial infarction and improve survival rates in mice. Additionally, GDF5 deficiency leads to increased myocardial fibrosis and decreased afterload. However, it also results in the occurrence of chronic adverse remodeling.
CARDIOVASCULAR PATHOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Martin Kveton, Lukas Hudec, Ivan Vykopal, Matej Halinkovic, Miroslav Laco, Andrea Felsoova, Wanda Benesova, Ondrej Fabian
Summary: This comprehensive review explores the transformative role of digital pathology and computational pathology, especially through machine learning, in the field of heart transplantation. These methodologies have the potential to enhance diagnostic outcomes and reduce observer variability by extracting valuable information from large datasets beyond human perceptual capabilities. However, challenges such as limited sample sizes, diverse data sources, and the absence of standardized protocols hinder the widespread adoption of these techniques.
CARDIOVASCULAR PATHOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Peiyue Zhang, Cuiyuan Huang, Haiyin Liu, Mengting Zhang, Li Liu, Yuhong Zhai, Jing Zhang, Jian Yang, Jun Yang
Summary: NFAT is a widely expressed transcriptional activator that is involved in regulating the immune system, heart and brain development, and mediating pathological processes such as cardiac hypertrophy. Oxidative stress, characterized by excessive production of reactive oxygen species, mitochondrial dysfunction, calcium overload, and subsequent lipid peroxidation, inflammation, and apoptosis, is associated with various pathological processes. Calcium overload activates NFAT through the calcium-calcineurin pathway, which is the main regulatory mode of NFAT factors. This review focuses on the effects of NFAT transcription factors on reactive oxygen species production, calcium overload, mitochondrial dysfunction, redox reactions, lipid peroxidation, inflammation, and apoptosis in response to oxidative stress. The aim is to provide a reference for understanding the functions and characteristics of NFAT in different stages of oxidative stress and related potential targets.
JOURNAL OF CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Sandeep Singh, Daniel P. Baars, Rupak Desai, Dyutima Singh, Sara-Joan Pinto-Sietsma
Summary: Lp(a) is associated with an increased risk of atrial fibrillation (AF), with higher risk observed in European populations and lower risk in the Chinese population. Further research is needed to confirm these findings.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Sikandar H. Khan, Anthony J. Perkins, Samreen Jawaid, Sophia Wang, Heidi Lindroth, Rebecca E. Schmitt, Jason Doles, Jason D. True, Sujuan Gao, Gideon A. Caplan, Homer L. Twigg III, Kenneth Kesler, Babar A. Khan
Summary: This study aimed to identify protein pathways associated with delirium post-esophagectomy. The findings revealed that coagulation factor IX and mannosyl-oligosaccharide 1,2-alpha-mannosidase were associated with delirium, while complement C2 and mannosyl-oligosaccharide 1,2-alpha-mannosidase were associated with delirium severity.
Review
Cardiac & Cardiovascular Systems
Hua Li, Tao Dong, Jinling Luan
Summary: Fluticasone propionate and salmeterol (FSC) are viable options for step-up treatment in asthmatic children, as they can reduce the incidence of asthma exacerbations and improve lung function. FSC treatment for more than 12 weeks shows a greater likelihood of reducing asthma exacerbations and decreasing the use of albuterol. There were no significant differences in drug-related adverse events between FSC and fluticasone propionate (FP) alone.
Review
Cardiac & Cardiovascular Systems
Patrizia Fughelli, Antonio V. Sterpetti
Summary: This report highlights the importance of collaboration and communication among scientists, showing that scientific progress can overcome prejudices, religious, and political differences, leading to common advancement and public benefits.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Sneha Annie Sebastian, Yashendra Sethi, Inderbir Padda, Gurpreet Johal
Summary: Canada has a high level of immigration, but little is known about the ethnic differences and cardiovascular disease (CVD) risk in the immigrant population. The significant ethnic diversity in Canada has resulted in unique CVD risk profiles for each ethnicity and country of birth. Understanding the ethnic differences in CVD risk could help promote effective health interventions and reduce the burden of morbidity and mortality associated with the disease.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Review
Cardiac & Cardiovascular Systems
Georgios Giannopoulos, Dimitrios Tachmatzidis, Dimitrios V. Moysidis, Dimitrios Filos, Magdalini Petridou, Ioanna Chouvarda, Vasileios P. Vassilikos
Summary: The P wave contains information about atrial electrical activity, but technical and biological reasons make it challenging to gather and utilize this information. However, simple ECG descriptors like P-wave dispersion have predictive value for assessing the risk of atrial fibrillation. More complex analysis methods and machine learning techniques may improve the accuracy and reliability of obtaining clinically useful information from the P wave.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
