Cardiac & Cardiovascular Systems

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Article Cardiac & Cardiovascular Systems

Socioclinical Phenotyping in Patients With Atherosclerotic Cardiovascular Disease: A Latent Class Analysis

Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir

Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Right Ventricular Thrombus on Echocardiography

Rukmini Roy, Brittney Guile, Deyu Sun, Teodora Szasz, Cristiane C. Singulane, Denis Nguyen, Abdulrahman Abutaleb, Roberto M. Lang, Karima Addetia

Summary: This study aimed to identify the echocardiographic and clinical features associated with the presence of right ventricular thrombi (RVTs). The results showed that most patients had dilated and dysfunctional right ventricles, and approximately 50% of RVTs were discovered in nonstandard imaging planes, suggesting that the presence of RVT might be underestimated in clinical practice.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Coronary Angiography and Chronic Total Occlusion Angioplasty in a Patient With Situs Inversus from the Right Radial Approach

Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg

Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Echocardiography Versus Magnetic Resonance Imaging Quantification and Novel Algorithm for Isolated Severe Tricuspid Regurgitation

Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai

Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Evaluation of MADIT-II Risk Stratification Score Among Nationwide Registry of Heart Failure Patients With Primary Prevention Implantable Cardiac Defibrillators or Resynchronization Therapy Devices

Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson

Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

The Factors Associated With Hyperkalemia-Induced Electrocardiogram Changes in the Outpatient Setting

Chadapa Sevamontree, Supreeya Jintajirapan, Pran Phakdeekitcharoen, Prin Vathesatogkit, Bunyong Phakdeekitcharoen

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Editorial Material Cardiac & Cardiovascular Systems

Major Adverse Cardiac Events After Fractional Flow Reserve, Instantaneous Wave-Free Ratio, or Angiography-Guided Revascularization in Atrial Fibrillation: A Retrospective Study

Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Echocardiographic Characteristics of Left and Right Ventricular Longitudinal Function in Patients With a History of Cardiac Surgery

Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota

Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Pericardiocentesis Outcomes in Patients With Pulmonary Hypertension: A Nationwide Analysis from the United States

Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis

Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

The Effect of Udenafil on Heart Rate and Blood Pressure in Adolescents With the Fontan Circulation

Jonathan B. Edelson, Victor Zak, David Goldberg, Greg Fleming, Andrew S. Mackie, Jyoti K. Patel, Matthew Files, Tacy Downing, Marc Richmond, Ben Acheampong, Mark Cartoski, Jon Detterich, Brian McCrindle, Kimberly McHugh, Jesse E. Hansen, Jonathan Wagner, Michael Di Maria, Angela Weingarten, Todd Nowlen, Ja Kyoung Yoon, Gi Beom Kim, Richard Williams, Robert Whitehill, Edward Kirkpatrick, Suellen Yin, Peter Ermis, Adam M. Lubert, Mario Stylianou, D'Andrea Freemon, Chenwei Hu, Olukayode D. Garuba, Peter Frommelt, Bryan H. Goldstein, Stephen Paridon, Ruchira Garg

Summary: The Fontan Udenafil Exercise Longitudinal (FUEL) trial showed that treatment with udenafil improved exercise performance in children with Fontan physiology. This study evaluated the effects of udenafil on vital signs in the FUEL trial cohort and found that it did not lead to clinically significant changes in heart rate or blood pressure.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Transcatheter Vacuum-Assisted Mass Extraction Versus Surgical Debridement for Vegetations in Tricuspid Valve Infective Endocarditis: A Meta- Analysis of Observational Studies

Andrew Geunwon Kim, Adolfo Martinez Salazar, Gabriel Panama, Moiz Saeed, Rand Sabanci, Khalid Saeed Al-Asad, Majid Yavari, Rohan Madhu Prasad, Supratik Rayamajhi, George S. Abela

Summary: This meta-analysis of five observational studies found no significant difference in overall mortality between transcatheter vacuum-assisted mass extraction (TVME) and standard surgical debridement (SD) for the treatment of tricuspid valve infective endocarditis (TVIE). However, prospective randomized controlled trials are necessary to further understand and compare the outcomes of these two approaches.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Influence of the Type of Disability and Sporting Discipline on Lipid Profile in a Cohort of Italian Paralympic Athletes

Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia

Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Editorial Material Cardiac & Cardiovascular Systems

Social Vulnerability and Hemopericardial Cardiovascular Death: Insight from the Centers for Disease Control and Prevention Databases

Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Electromechanical Window and Spontaneous Ventricular Tachyarrhythmias in Takotsubo Syndrome

Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin

Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Understanding the Burden of 30-Day Readmission in Patients With Both Primary and Secondary Diagnoses of Heart Failure: Causes, Timing, and Impact of Co-Morbidities

Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai

Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Reversed Septal Curvature Is Associated With Nonsustained Ventricular Tachycardia in Hypertrophic

Ya He, Jianzhong Zhou

Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Pericardial Adipose Tissue Thrombospondin-1 Associates With Antiangiogenesis in Ischemic Heart Disease

Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce

Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Comparative Effect of Loop Diuretic Prescription on Mortality and Heart Failure Readmission

Arti V. Virkud, Patricia P. Chang, Michele Jonsson Funk, Abhijit V. Kshirsagar, Jessie K. Edwards, Virginia Pate, Michael R. Kosorok, Emily W. Gower

Summary: This study compared the effects of prescribing different loop diuretics (torsemide, furosemide, and bumetanide) at the time of hospital discharge for heart failure patients. The results showed that torsemide had the lowest risk of all-cause mortality and combined outcomes, while bumetanide had a slightly higher risk compared to furosemide.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Review Cardiac & Cardiovascular Systems

The Role of Natriuretic Peptides in Predicting Adverse Outcomes After Cardiac Surgery: An Updated Systematic Review

Reddi Ashwin Rao, Sonu Sam Varghese, Farzan Ansari, Aditya Rao, Eric Meng, Mohammad El-Diasty

Summary: This systematic review evaluates the utility of natriuretic peptides as predictive biomarkers for adverse outcomes after cardiac surgery. The results suggest that preoperative levels of BNP and N-terminal prohormone BNP are associated with increased risk of mortality, postoperative heart failure, kidney injury, and longer intensive care unit stay. However, their predictive value for postoperative arrhythmias and myocardial infarction is less established.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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Article Cardiac & Cardiovascular Systems

Evaluation of Right-Side Filling Pressure in Patients With Obesity With Heart Failure Using Handheld

Aiham Albaeni, Mohit Sharma, Khaled F. Chatila, Mostafa Shalaby, Masood Ahmad, Wissam I. Khalife

Summary: The study aims to evaluate the accuracy of handheld ultrasound score in assessing right atrial pressure in patients with obesity and heart failure. The results showed that in obese patients, a 3-point score including assessment of the right internal jugular vein performed better than a 2-point score only including inferior vena cava assessment.

AMERICAN JOURNAL OF CARDIOLOGY (2024)

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