Andrology

20.9K Papers

Follow See full results

Review Andrology

Frailty of Prostate Cancer Patients Receiving Androgen Deprivation Therapy: A Scoping Review

Jeongok Park, Gi Wook Ryu, Hyojin Lee, Young Deuk Choi, Youngkyung Kim

Summary: This study aimed to explore frailty experienced by patients with prostate cancer receiving androgen deprivation therapy. The results showed variations in the definition and intervention measures of frailty, and frailty was found to be associated with factors such as age, metastases, comorbidities, and physiological indicators. Further research is needed to develop effective interventions and consider the psychological, cognitive, and social domains of frailty.

WORLD JOURNAL OF MENS HEALTH (2023)

添加到收藏夹

Article Andrology

A transparent synthetic peptide hydrogel as a haemostatic agent in athermal nerve sparing robot-assisted radical prostatectomy: an observational study

Kale Munien, William Harrison, Joshua Paul, Devang Desai

Summary: The observational study suggests that PuraStat (R) is a safe haemostatic agent in RARP with comparable perioperative bleeding outcomes, long-term urinary outcomes and a high level of intraoperative user satisfaction. Further investigation is needed to assess its effects on EF.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2023)

添加到收藏夹

Article Andrology

Is testosterone deficiency a predictive factor for recurrence of urethral stricture?

Emrah Ozsoy, Musab Ali Kutluhan, Emre Tokuc, Ridvan Kayar, Samet Demir, Mehmet Akyuz, Metin Ishak Ozturk

Summary: Testosterone levels and ratios may serve as predictive factors for identifying recurrent cases in primary short-segment bulbar strictures.

ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Polyamines modulate mouse sperm motility

Lorena Rodriguez-Paez, Charmina Aguirre-Alvarado, German Chamorro-Cevallos, Alcantara-Farfan Veronica, Calderon-Espinosa Sandra Irel, Castillo-Perez Hugo, Carlos Armando Garcia-Perez, Guadalupe Elizabeth Jimenez-Gutierrez, Joaquin Cordero-Martinez

Summary: This study evaluated the effects of spermine, spermidine, and putrescine on sperm motility, capacitation, and acrosome reaction. The results showed that polyamines significantly decreased these parameters and may act by inhibiting the activity of sAC. Furthermore, polyamines also caused a decrease in cAMP concentration.

SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE (2023)

添加到收藏夹

Article Andrology

MEHP activates JNK to inhibit the migration of human foreskin fibroblasts

Hu Zhang, Xuan Yi, Wei Hu, Guoqiang Zhu, Xiaowen Fu, Wei Jin, Long Qin, Mingyong Li

Summary: This study investigates the impact of MEHP on the proliferation, apoptosis, and migration of HFF-1 cells, as well as the role of the JNK signaling pathway in cell migration. The results show that MEHP exposure leads to increased apoptosis and decreased migration ability in HFF-1 cells, and the activation of the JNK signaling pathway is positively correlated with the concentration of MEHP exposure.

SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE (2023)

添加到收藏夹

Article Andrology

Identification of ferroptotic genes and phenotypes in idiopathic nonobstructive azoospermia

Chen Liao, Tian-Wen Peng, Xiao-Min Li, Zhi-Cong Chen, Mu-Ye Wang, Xin Ye, Yu Lan, Xin Fu, Geng An

Summary: This study identified ferroptosis-related genes and phenotypes in idiopathic nonobstructive azoospermia (iNOA) through gene expression analysis. Four potential biomarkers for iNOA were identified and the ferroptotic phenotypes were observed in iNOA patients through morphologic and biochemical assays.

SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE (2023)

添加到收藏夹

Letter Andrology

The role of homozygous LOF variant of the PNLDC1 gene in oligo-astheno-teratozoospermia (OAT) and male infertility

Zi-Xin Cheng, Li Du, Zuping He

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Low XIST expression in Sertoli cells of Klinefelter syndrome patients causes high susceptibility of these cells to an extra X chromosome

Liang-Yu Zhao, Peng Li, Chen-Cheng Yao, Ru-Hui Tian, Yu-Xin Tang, Yu-Zhuo Chen, Zhi Zhou, Zheng Li

Summary: This study reveals the transcriptome changes in different testicular cell types of Klinefelter syndrome (KS) patients. Sertoli cells show the largest transcriptome changes in KS patients. Further research indicates that the loss of X-inactive-specific transcript (XIST) in Sertoli cells leads to an increase in X chromosome gene levels and disrupts their transcription pattern and cellular function. This phenomenon is not observed in other somatic cells. This study provides an important theoretical basis for explaining the heterogeneity of testicular atrophy in KS patients and subsequent related treatment.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Identification of a novel splice site mutation in the DNAAF4 gene of a Chinese patient with primary ciliary dyskinesia

Yang Xu, Jing Wang, Ji-Hai Liu, Qing-Qiang Gao, Bing Wang, Zhi-Peng Xu

Summary: This study identified novel biallelic variants causing primary ciliary dyskinesia (PCD) and asthenoteratozoospermia, expanding the range of DNAAF4 pathogenic variants associated with PCD and contributing to the understanding of the etiology of PCD.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Ipsilateral and contralateral patent processus vaginalis in pediatric patients with a unilateral nonpalpable testis

Ming-Ming Yu, Hua Xie, Yi-Chen Huang, Yi-Qing Lv, Fang Chen, Xiao-Xi Li

Summary: This study aimed to investigate the incidence of patent processus vaginalis (PPV) in pediatric patients with a unilateral nonpalpable testis and explore the associated factors. The study found that the incidence of ipsilateral PPV was significantly related to the side, development, and position of the testis, while it was independent of these factors on the contralateral side.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Correction Andrology

Generation of Leydig-like cells: approaches, characterization, and challenges (vol 24, pg 335, 2022)

Zhao-Hui Li, Jun-Dong Lu, Shi-Jun Li, Hao-Lin Chen, Zhi-Jian Su

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Genotype-phenotype correlations, surgical selections, and postoperative complications of 5α-reductase 2 deficiency in 69 children with hypospadias

Xu Wen, Li-Jun Fan, Wei-Ping Zhang, Xin Ni, Chun-Xiu Gong

Summary: This study analyzed the relationship between genotype-phenotype, surgical selections, and postoperative complications in patients with 5 alpha-reductase 2 deficiency. Preoperative hormone stimulation was found to have a positive effect on penile development, and certain mutations were associated with higher external masculinization scores and less severe hypospadias.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

MiOXSYS® and OxiSperm® II assays appear to provide no clinical utility for determining oxidative stress in human sperm-results from repeated semen collections

Patience Castleton, Prabin Gyawali, Nicola Mathews, Shadrack Mulinge Mutuku, David James Sharkey, Nicole Olivia McPherson

Summary: This study found that the MiOXSYS(R) and OxiSperm(R) II systems for measuring sperm oxidative stress may have limited diagnostic potential. There were no significant associations between these systems and sperm function or oxidative stress. This may be due to limited understanding of their biochemistry and clinical application.

ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Ultrasonographic evaluation of the rete testis thickness: a promising approach to differentiate obstructive from nonobstructive azoospermia

Xin Li, Ru-Hui Tian, Peng Li, Chun-Xiao Li, Ming-Hua Yao, Chen-Cheng Yao, Xiao-Bo Wang, Li-Ren Jiang, Zheng Li, Rong Wu

Summary: This study evaluated the ability of rete testis thickness and testicular shear wave elastography to differentiate obstructive azoospermia from nonobstructive azoospermia. The results showed that ultrasonographic RTT evaluation performed better than SWE in distinguishing the two conditions.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Factors influencing the sperm retrieval rate of microdissection testicular sperm extraction in patients with nonmosaic Klinefelter syndrome

De-Feng Liu, Han Wu, Zhe Zhang, Kai Hong, Hao-Cheng Lin, Jia-Ming Mao, Hui-Yu Xu, Lian-Ming Zhao, Hui Jiang

Summary: This study investigated the factors affecting the sperm retrieval rate of micro-TESE in patients with nonmosaic KS. The results showed that age and anti-Mullerian hormone levels were better predictors for the sperm retrieval rate.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

The combined role of MRI prostate and prostate health index in improving detection of significant prostate cancer in a screening population of Chinese men

Peter K. F. Chiu, Thomas Y. T. Lam, Chi-Fai Ng, Jeremy Y. C. Teoh, Carmen C. M. Cho, Hiu-Yee Hung, Cindy Hong, Monique J. Roobol, Winnie C. W. Chu, Samuel Y. S. Wong, Joseph J. Y. Sung

Summary: The use of prostate health index (PHI) and magnetic resonance imaging (MRI) can effectively diagnose clinically significant prostate cancer (csPCa) while reducing unnecessary biopsies in PCa screening.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients

Wei-Jie Song, Ji-Wei Huang, Yuan Liu, Wei Ding, Zhi Long, Le-Ye He

Summary: This study investigated the impact of the COVID-19 pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome. The study found that more patients developed severe erectile dysfunction due to depression and anxiety caused by the pandemic. Additionally, patients with moderate-to-severe erectile dysfunction exhibited more apparent symptoms of anxiety and depression, forming a vicious cycle.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Abnormal cortical surface-based spontaneous and functional connectivity in the whole brain in lifelong premature ejaculation patients

Si-Yan Xing, Jia-Ming Lu, Yue-Hui Jiang, Tong Wang, Guang-Jun Du, Bai-Bing Yang, Qing-Qiang Gao, Bin Wang, Ning Wu, Chun-Lu Xu, Tao Song, Yu-Tian Dai

Summary: The recent research has identified structural and functional abnormalities in the cerebral cortex of patients with premature ejaculation (PE), indicating their significance in the physiological mechanisms of PE. Utilizing functional magnetic resonance imaging (fMRI), the study explored these neural mechanisms and found specific brain regions associated with the neurobiological underpinnings of PE.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

High ligation of the hernia sac in open nonmesh inguinal herniorrhaphy is an important cause of iatrogenic vas deferens injury

Jun Zhao, Xiao-Qiang Zhai, He-Cheng Li, Tie Chong

Summary: This study analyzed the characteristics and causes of vas deferens injuries following open nonmesh hernia repair, confirming obstructed vas deferens site intraoperatively. The results showed a high patency rate of 85.3% for vasovasostomies and emphasized the need for caution during high ligation of the hernial sac in open nonmesh inguinal herniorrhaphy.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

Article Andrology

Altered microRNA expression profiles of human spermatozoa in normal fertile men of different ages

Ming-Jia Zhao, Yao-Nan Zhang, Yong-Ping Zhao, Xian-Bing Chen, Bao-Sheng Han, Ning Ding, Yi-Qun Gu, Shu-Song Wang, Jing Ma, Mei-Ling Liu

Summary: This study analyzed the expression profiles of miRNAs in spermatozoa from men of different ages and identified differentially expressed miRNAs and their target genes associated with age. MiRNAs play a key role in male fertility changes with increasing age, providing new evidence for the study of the mechanism of age-related male fertility decline.

ASIAN JOURNAL OF ANDROLOGY (2023)

添加到收藏夹

«
1
2
3
4
5
»

See full results

Related Categories

Allergy (148.5K) Anatomy & Morphology (60.4K) Behavioral Sciences (170.8K) Cardiac & Cardiovascular Systems (1.1M) Nutrition & Dietetics (363.1K) Pathology (375.2K) Public, Environmental & Occupational Health (1M) Substance Abuse (127.4K)

© Peeref 2019-2024. All rights reserved.