Article
Anatomy & Morphology
Joe Iwanaga, Vishram Singh, Sen Takeda, Julius Ogeng'o, Hee-Jin Kim, Janusz Morys, Kumar Satish Ravi, Domenico Ribatti, Paul A. Trainor, Jose Ramon Sanudo, Nihal Apaydin, Anu Sharma, Heather F. Smith, Jerzy A. Walocha, Ahmed M. S. Hegazy, Fabrice Duparc, Friedrich Paulsen, Mariano Del Sol, Philip Adds, Stephane Louryan, Valeria Paula Sassoli Fazan, R. K. Boddeti, R. Shane Tubbs
Summary: This article discusses the issue of the lack of ethical use statements or varied language used in anatomical research regarding donor cadavers. It introduces a set of standardized language developed by 22 editors-in-chief of anatomical journals, aiming to standardize how the ethical use of donor cadavers is acknowledged in studies using human cadaveric tissues.
Review
Anatomy & Morphology
Sven Jonckheere, Jamie Adams, Dominic De Groote, Kyra Campbell, Geert Berx, Steven Goossens
Summary: Metastasis, the spread of cancer cells to distant sites, is the primary cause of cancer morbidity and mortality. During the initial stages of metastasis, cancer cells undergo EMT, becoming migratory and invasive mesenchymal-like cells with stem cell properties. Targeting EMT in therapy has the potential to prevent cancer cell invasion and dissemination, reduce cancer stemness, and enhance the effectiveness of chemotherapy.
CELLS TISSUES ORGANS
(2022)
Article
Anatomy & Morphology
Marriam Nawaz, Zahid Mehmood, Tahira Nazir, Rizwan Ali Naqvi, Amjad Rehman, Munwar Iqbal, Tanzila Saba
Summary: This study presents a fully automated method for segmenting melanoma skin cancer using deep learning and fuzzy k-means clustering, aiming to aid in the early diagnosis and treatment of this disease. Evaluation on three standard datasets shows that the method outperforms state-of-the-art approaches in skin lesion recognition and segmentation, demonstrating robustness.
MICROSCOPY RESEARCH AND TECHNIQUE
(2022)
Review
Anatomy & Morphology
Nicola Palomero-Gallagher, Katrin Amunts
Summary: Emotions are valenced mental and physiological responses that can influence behavior, supported by large-scale integrated neuronal networks with potential lateralization in processing. The controversy lies in the specific role of each hemisphere, with hypotheses ranging from overall hemispheric specialization to dynamic models incorporating multiple interrelated networks.
BRAIN STRUCTURE & FUNCTION
(2022)
Article
Anatomy & Morphology
Alessio Alesci, Simona Pergolizzi, Angelo Fumia, Concetta Calabro, Patrizia Lo Cascio, Eugenia Rita Lauriano
Summary: This study used goldfish as an experimental model to characterize mast cells in the intestine. The results demonstrate the active role of mast cells in the immune response, using highly conserved antibody labeling.
Article
Anatomy & Morphology
Chu-Chung Huang, Edmund T. Rolls, Jianfeng Feng, Ching-Po Lin
Summary: HCPex is a modified and extended version of the surface-based Human Connectome Project-MultiModal Parcellation atlas, providing a user-friendly approach for volumetric neuroimaging software. It includes 66 additional subcortical areas and labeled coronal views of the human brain, enhancing the original atlas with 360 cortical areas.
BRAIN STRUCTURE & FUNCTION
(2022)
Review
Anatomy & Morphology
Pei-Yu Chu, Angele Pei-Fern Koh, Jane Antony, Ruby Yun-Ju Huang
Summary: The chick CAM model has been a valuable alternative in oncology research, showing increased xenograft take rates and retention of tumor heterogeneity. Various imaging techniques and data analysis have been widely applied to study tumor metastasis, angiogenesis, and therapeutic response to novel agents.
CELLS TISSUES ORGANS
(2022)
Article
Anatomy & Morphology
Emily J. Lessner, Casey M. Holliday
Summary: This study explores the anatomical patterns of cranial nerves in different developmental stages of alligators using three-dimensional models and CT imaging technology for the first time. The findings reveal the growth and development patterns of alligator cranial nerves, which are important for understanding neurological diversity and the evolution and developmental homology of cranial regions.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY
(2022)
Review
Anatomy & Morphology
Alessio Alesci, Simona Pergolizzi, Patrizia Lo Cascio, Angelo Fumia, Eugenia Rita Lauriano
Summary: Neurodegenerative diseases affect a significant percentage of the population, with lower vertebrates retaining the ability to regenerate the nervous system. The regenerative ability of the nervous system decreases with phylogenetic distance, and there are differences in neuronal regeneration processes among different classes of vertebrates.
Article
Anatomy & Morphology
Ayalur R. Subbalakshmi, Sarthak Sahoo, Kuheli Biswas, Mohit Kumar Jolly
Summary: Epithelial-mesenchymal plasticity plays a crucial role in aggressive tumor progression, and cells in hybrid epithelial/mesenchymal phenotype exhibit greater aggressiveness. The study reveals that SLUG can stabilize cells in the hybrid epithelial/mesenchymal phenotype, functioning as a phenotypic stability factor. This finding has important implications for understanding metastasis mechanisms.
CELLS TISSUES ORGANS
(2023)
Review
Anatomy & Morphology
Bruno Rossion, Aliette Lochy
Summary: The current research does not support the hypothesis that neural competition in the left ventral occipito-temporal cortex with selective representations of letter strings causes right hemispheric lateralization of face recognition. The relationship between literacy and right hemispheric lateralization of face recognition remains unclear, and further exploration is needed to better understand the underlying mechanisms.
BRAIN STRUCTURE & FUNCTION
(2022)
Review
Anatomy & Morphology
Samia Benyahia, Boudjelal Meftah, Olivier Lezoray
Summary: The study found that using pre-trained convolutional neural networks as feature extractors achieved good classification results on two datasets.
Review
Anatomy & Morphology
Stephanie J. Forkel, Patrick Friedrich, Michel Thiebaut de Schotten, Henrietta Howells
Summary: Inter-individual differences in brain anatomy can significantly impact treatment procedures and patient outcomes. Studying brain connections through diffusion tractography may be an ideal method to capture this variability. While tractography has shown promise in correlating with cognitive functions and pathologies, there are methodological limitations and biases in the literature to consider.
BRAIN STRUCTURE & FUNCTION
(2022)
Review
Anatomy & Morphology
Agnes Desroches-Castan, Emmanuelle Tillet, Claire Bouvard, Sabine Bailly
Summary: BMPs are a group of cytokines that play diverse roles in the body. In humans, there are 15 BMP ligands that initiate cellular signaling by forming complexes with specific receptors. Certain receptors have been directly linked to rare vascular diseases.
DEVELOPMENTAL DYNAMICS
(2022)
Article
Anatomy & Morphology
Wenying Zhang, Qiongwei Wu, Yu Liu, Xujie Wang, Chengbin Ma, Weipei Zhu
Summary: This study reveals the mechanism of HOTAIR involvement in cervical cancer, showing that it promotes tumor cell migration, proliferation, and chemoresistance through the miR-29b/PTEN/PI3K axis.
CELLS TISSUES ORGANS
(2022)
Review
Anatomy & Morphology
Nour S. Erekat
Summary: Neurodegenerative disorders involve the progressive loss of specific populations of neurons, with apoptosis playing a role in diseases such as Parkinson's, Alzheimer's, Huntington's, and ALS. This review examines the morphological features, mediators, and regulators of cellular apoptosis, highlighting evidence of neuronal apoptotic death in these diseases. The potential for therapeutic agents to modify the apoptotic pathway and delay disease progression is also discussed.
Article
Anatomy & Morphology
Bardia Mortezagholi, Emad Movahed, Amirhossein Fathi, Milad Soleimani, Armita Forutan Mirhosseini, Negar Zeini, Mehrdad Khatami, Mahin Naderifar, Bahman Abedi Kiasari, Mehran Zareanshahraki
Summary: In this study, silver-doped zinc oxide nanoparticles were synthesized and characterized. It was found that the addition of silver changed the size of the nanoparticles and improved the antimicrobial activity. Therefore, these nanoparticles can be used as a new antibacterial agent in medical applications.
MICROSCOPY RESEARCH AND TECHNIQUE
(2022)
Review
Anatomy & Morphology
Joe Iwanaga, Hiroshi Fukuoka, Nobuko Fukuoka, Hirokazu Yutori, Soichiro Ibaragi, R. Shane Tubbs
Summary: This review analyzed cases of herpes zoster (HZ) infection following COVID-19 vaccine administration, including two cases of oral HZ. A total of 399 cases were identified, showing dermatomes mimicking the regular distribution pattern of HZ. Some patients with a history of varicella zoster virus vaccination also developed HZ following COVID-19 vaccination.
Review
Anatomy & Morphology
John B. Pawlak, Gerard C. Blobe
Summary: TGF-beta superfamily signaling is often modified by co-receptors, leading to dynamic effects on SMAD-mediated pathways. The release of soluble forms of these co-receptors can further modulate signaling, potentially antagonizing membrane-bound receptors.
DEVELOPMENTAL DYNAMICS
(2022)
Review
Anatomy & Morphology
Emiliano Bruner, Alexandra Battaglia-Mayer, Roberto Caminiti
Summary: Traditional and new disciplines suggest that the parietal lobe underwent considerable expansion during human evolution. Various studies have shown increased globularity of the braincase and bulging of the parietal region in modern humans compared to other human species. The parietal cortex is believed to play a significant role in human-specific behaviors related to visuospatial capacity, technological integration, self-awareness, numerosity, mathematical reasoning, and language.
BRAIN STRUCTURE & FUNCTION
(2023)
