Anatomy & Morphology

Article Anatomy & Morphology

Electroacupuncture modulates gut microbiota in mice: A potential target in postoperative cognitive dysfunction

Binbin Zhu, Yanling Zhou, Weijian Zhou, Chunqu Chen, Jianhua Wang, Shujun Xu, Qinwen Wang

Summary: This study investigated whether electroacupuncture (EA) can alleviate postoperative cognitive dysfunction (POCD) by modulating gut microbial dysbiosis. The results showed that EA treatment improved learning and spatial memory deficits in POCD patients and regulated the changes in intestinal flora. Additionally, EA treatment also relieved blood-brain barrier and intestinal barrier dysfunction, thus reducing hippocampal inflammation.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2023)

Review Anatomy & Morphology

Reconstructing the subcephalic musculature in Pucapampella and Ichthyostega

Alexander N. Kuznetsov, Nadezhda V. Kryukova

Summary: This study presents the reconstruction and functional evolution of the subcephalic musculature in various species of primitive fishes and early tetrapods. The muscular structure in these species played a role in holding together the anterior and posterior parts of the neurocranium during interactions with prey. In more advanced species, such as lungfish and certain fish species, the subcephalic muscles are involved in actively depressing the anterior part of the neurocranium. The majority of cartilaginous and bony fishes have reduced or lost the subcephalic musculature, but some species like hexanchid sharks and Polypterus retain specific subcephalic muscles.

JOURNAL OF MORPHOLOGY (2023)

Article Anatomy & Morphology

Delta like Non-Canonical Notch Ligand 2 inhibits chondrogenic differentiation and cell proliferation of bone marrow mesenchymal stem cells through the Notch1 signaling pathway

Yanan Chen, Yaru Liu, Renbo Zhang, Yanjie Mao, Axiang He, Wanjun Liu

Summary: DLK2 negatively regulates chondrogenic differentiation and cell proliferation in BMSCs by inhibiting the Notch1 signaling pathway.

TISSUE & CELL (2023)

Article Anatomy & Morphology

Evaluation of histologic, antiapoptotic and antioxidant effects of melatonin against the acute ocular toxicity of Cisplatin

Osman Ahmet Polat, Derya Karabulut, Zeynep Akkul, Murat Unsal, Meryem Sayan, Fatih Horozoglu, Cem Evereklioglu, Hidayet Sener

Summary: This study found that cisplatin significantly increased toxic effect on the cornea, but melatonin had a partial protective effect against this damage.

TISSUE & CELL (2023)

Article Anatomy & Morphology

CREB1 alleviates the apoptosis and potentiates the osteogenic differentiation of zoledronic acid-treated human periodontal ligament stem cells via up-regulating VEGF

Yao Duan, Chanyuan Jin, Yuwei Wu, Yan Chen, Minjuan Zhang, Jun Qian, Ting Shuai, Jian Li, Huimin Chen, Dan Li

Summary: This study investigated the effects of CREB1 on periodontitis and its possible mechanism of action. The findings suggest that elevation of CREB1 can enhance the viability and osteogenic differentiation of PDLSCs, while inhibiting apoptosis. It was also found that CREB1 can bind to the VEGF promoter and transcriptionally activate VEGF expression. Furthermore, the absence of VEGF partially stimulates apoptosis and suppresses osteogenic differentiation in CREB1-overexpressing PDLSCs treated with ZA.

TISSUE & CELL (2023)

Article Anatomy & Morphology

UPK1B promoted the invasion and stem cell characteristics of non-small cell lung cancer cells by modulating c-myc/Sox4 axis

Yiyang Liu, Li Ding, Chunwei Li, Lei Heng, Jianjun Chen, Yulong Hou

Summary: UPK1B enhances the proliferation, invasion, and stem cell characteristics of NSCLCs by activating the c-myc/UPK1B axis. Overexpression of Sox4 rescues the proliferation and invasion of NSCLCs suppressed by UPK1B knockdown.

TISSUE & CELL (2023)

Article Anatomy & Morphology

A standardized protocol for needle placement in the infraspinatus muscle: an anatomical perspective

Ji-Hyun Lee, Kang-Woo Lee, Kyu-Ho Yi, You-Jin Choi, Hye-Won Hu, Hyung-Jin Lee

Summary: This study evaluated the morphology of the three parts of the infraspinatus muscle based on surface landmarks and proposed the most effective fine-wire electrode insertion technique and sites. The results showed that the superior, middle, and inferior parts of the infraspinatus muscle have different anatomical locations. Targeting the superior and middle parts for electrode insertion is relatively straightforward, while targeting the inferior part is more challenging.

SURGICAL AND RADIOLOGIC ANATOMY (2023)

Article Anatomy & Morphology

Salvianolic acid B exerts protective effects against Aβ-induced neuroinflammation through the inhibition of NLRP3 inflammasome activation and switching of M1/M2 polarization

Yuan Zhao, Xin Liu, Xiang Liu, Jian Zhang, Yidan Zhang, Ya Wen, Guofeng Yang

Summary: This study demonstrated that Salvianolic acid B (SalB) has neuroprotective effects against Aβ1-42-induced neuroinflammation. It was found that SalB downregulates NLRP3 expression and promotes M2 microglial polarization, suggesting its potential as a novel therapeutic candidate for Alzheimer's disease (AD).

TISSUE & CELL (2023)

Article Anatomy & Morphology

In situ hybridization analysis of odorant receptor expression in the olfactory organ of the pig-nosed turtle Carettochelys insculpta

Shoko Nakamuta, Miho Itoh, Masanori Mori, Masanori Kurita, Zicong Zhang, Masato Nikaido, Masao Miyazaki, Takuya Yokoyama, Yoshio Yamamoto, Nobuaki Nakamuta

Summary: The olfactory organ of the pig-nosed turtle differs from other turtles in its structure and distribution of olfactory receptor neurons. The absence of glands and the presence of both ciliated and microvillous receptor neurons suggest a unique olfactory system. The expression patterns of odorant receptors further support the division of the olfactory organ into two regions.

TISSUE & CELL (2023)

Article Anatomy & Morphology

Relationship between long non-coding RNA MALAT1 and HOTAIR expression with sperm parameters, DNA and malondialdehyde levels in male infertility

Afsaneh-Jaberi Asl, Mohammadreza Sharifi, Abolfazl Dashti, Gholam reza Dashti

Summary: The study found that the expression of lncRNA MALAT1 and HOTAIR is related to sperm quality, DNA fragmentation, and MDA levels. The expression level is positively correlated with sperm motility and morphology, and negatively correlated with DNA damage and MDA levels.

TISSUE & CELL (2023)

Article Anatomy & Morphology

Alleviation of doxorubicin-induced cardiotoxicity in rat by mesenchymal stem cells and olive leaf extract via MAPK/ TNF-α pathway: Preclinical, experimental and bioinformatics enrichment study

Mahrous A. Ibrahim, Athar M. Khalifa, Noha M. Abd El-Fadeal, Rehab I. Abdel-Karim, Ayman F. Elsharawy, Alia Ellawindy, Heba M. Galal, Eman H. Nadwa, Mohamed A. Abdel-Shafee, Rania A. Galhom

Summary: Both BM-MSCs and OLE have an ameliorating effect on DOX-induced cardiac lesions, with BM-MSCs showing a greater influence. The DOX-treated group exhibited severe myocardial fibrosis, cell degeneration, increased vimentin, and decreased CD-31 expression. Group V showed a considerable beneficial effect compared to Group IV.

TISSUE & CELL (2023)

Article Anatomy & Morphology

Assessment of breast cytoarchitecture and its associated axillary lymph node status under normal and pathological conditions in Egyptian women

Omnia Mansour, Amani Kazem, Abeer El Wakil

Summary: This study compares the features of neoplastic cancer cells in different grades of invasive ductal carcinoma (IDC) patients with their corresponding normal cells. It highlights the importance of accurate specimen evaluation for treatment choice and decision-making.

TISSUE & CELL (2023)

Article Anatomy & Morphology

The marked dextro-dominance causes accentuated morphophysiological variations in the female reproductive organs of the bat Molossus molossus

Juliana F. Ferraz, Rodrigo S. de Oliveira, Cornelio S. Santiago, Emilia M. Soares, Eliana Morielle-Versute, Sebastiao R. Taboga, R. Taboga, Mateus R. Beguelini

Summary: This study evaluated variations in the female reproductive organs of M. molossus during different reproductive phases. The results showed distinct morphofunctional asymmetry in the reproductive system, with a marked dominance of the right side. The right ovaries exhibited follicles at different stages of development, interstitial glands, and a small but persistent corpus luteum. Ovulation occurred exclusively in the right ovary, while follicular development in the left ovary was limited. Implantation was preferentially in the right uterine horn, and the placenta was formed by two distinct chorioallantoic portions. The uterine cervix and vagina showed minimal variation in different reproductive stages.

TISSUE & CELL (2023)

Article Anatomy & Morphology

Standardization, objectification, and essence research of traditional Chinese medicine syndrome: A 15-year bibliometric and content analysis from 2006 to 2020 in Web of Science database

Ji-Yan Liu, Xiang Li

Summary: The standardization, objectification, and essence research of traditional Chinese medicine (TCM) syndrome have influenced the modernization and international development of TCM syndrome. High-yield institutions and high-impact authors in China have made significant contributions to TCM syndrome research. Emerging trends in TCM syndrome research include constructing diagnostic models with multiple indexes, verifying the connotation of TCM syndrome, and conducting interdisciplinary research.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2023)

Article Anatomy & Morphology

Electroacupuncture at BL15 attenuates chronic fatigue syndrome by downregulating iNOS/NO signaling in C57BL/6 mice

Yang Zhu, Jingya Wang, Lin Yao, Yunxuan Huang, Haitao Yang, Xiaojiang Yu, Xinghua Chen, Yongjun Chen

Summary: This study investigated the effects of electroacupuncture (EA) on cardiac function in a chronic fatigue syndrome (CFS) mouse model. The results showed that EA improved motor and cardiac function in CFS mice, and this effect may be associated with the down-regulation of the iNOS/NO signaling pathway.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2023)

Article Anatomy & Morphology

Gentisic acid ameliorates cisplatin-induced reprotoxicity through suppressing endoplasmic reticulum stress and upregulating Nrf2 pathway

Ahmet Mentese, Selim Demir, Sevdegul Aydin Mungan, Nihal Turkmen Alemdar, Elif Ayazoglu Demir, Yuksel Aliyazicioglu

Summary: This study demonstrated the therapeutic effect of gentisic acid (GTA) against cisplatin-induced testicular toxicity in rats. GTA ameliorated oxidative stress, inflammation, endoplasmic reticulum stress, and apoptosis caused by cisplatin administration. The activation of the Nrf2 pathway played a key role in this therapeutic effect of GTA.

TISSUE & CELL (2023)

Article Anatomy & Morphology

HMGB1/PTEN/PI3K axis participates in the peripheral immune cell differentiation in two representative TCM syndromes of chronic hepatitis B patients(sic)(sic)(sic)

Cen Jiang, Xia Li, Chao Liu, Guiyu Li, Yanfeng Zheng, Lushuang Xie, Wenjun Wu, Quansheng Feng

Summary: This study explored the immunoregulatory mechanisms of liver depression and spleen deficiency syndrome (LDSDS) and spleen-gastric damp-heat syndrome (SGDHS) in chronic hepatitis B (CHB). The results revealed significant differences in T lymphocyte levels and expression of HMGB1/PTEN/PI3K axis proteins between the two syndromes. HMGB1/PTEN/PI3K axis may play an important role in regulating the immune differences between LDSDS and SGDHS.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2023)

Article Anatomy & Morphology

Electroacupuncture restores intestinal mucosal barrier through TLR4/NF-κB p65 pathway in functional dyspepsia-like rats(sic)(sic)(sic)

Dan Wang, Jinling Zhang, Daye Yang, Junying Wang, Jia Li, Yongli Han, Zhaoxia Kang, Hongxing Zhang

Summary: This study aimed to investigate the effects of electroacupuncture (EA) and its mechanism on the intestinal mucosal barrier in a rodent model of functional dyspepsia (FD). The results showed that EA treatment improved body weight and food intake in rats with FD-like symptoms. It also reduced the expression of inflammatory markers in the duodenum and serum, while increasing the expression of proteins associated with the intestinal barrier. The findings suggest that EA is more effective than acupuncture in improving the intestinal mucosal barrier in FD.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2023)

Article Anatomy & Morphology

Medial-type persistent trigeminal artery and ipsilateral posterior communicating artery supplying bilateral posterior cerebral arteries combined with an aberrant right subclavian artery and bicarotid trunk

Akira Uchino, Ryushi Kondo

Summary: This article describes a case of medial-type persistent trigeminal artery (PTA) with multiple arterial variations. The patient had an unruptured cerebral aneurysm detected on magnetic resonance (MR) imaging, which was successfully treated by coil embolization. The study found an association between PTA and a large ipsilateral posterior communicating artery (PCoA), as well as the presence of an aberrant right subclavian artery with a bicarotid trunk, which has not been reported before. Therefore, it is important to evaluate the aortic arch and its branches before catheterization of the cerebral arteries to avoid catheterization failure.

SURGICAL AND RADIOLOGIC ANATOMY (2023)

Article Anatomy & Morphology

Compartments of the crural fascia: clinically relevant ultrasound, anatomical and histological findings

S. Ortiz-Miguel, M. Miguel-Perez, J. Blasi, A. Perez-Bellmunt, J. C. Ortiz-Sagrista, I. Moller, J. L. Agullo, P. Iglesias, C. Martinoli

Summary: This study examines the ultrasound and anatomical features of the crural fascia in relation to compartment syndrome in the leg. It finds important clinical relationships and highlights the significance of protecting these structures during surgical treatment.

SURGICAL AND RADIOLOGIC ANATOMY (2023)