Anatomy & Morphology

Article Anatomy & Morphology

Localization of vasoactive intestinal peptide and toll-like receptor 2 immunoreactive cells in endostyle of urochordate Styela plicata (Lesueur, 1823)

Alessio Alesci, Simona Pergolizzi, Patrizia Lo Cascio, Gioele Capillo, Eugenia Rita Lauriano

Summary: The endostyle is the first component of the ascidian digestive tract, divided into nine zones with distinct cells and functions. Immunohistochemical investigation revealed the presence of immune cells in the endostyle of Styela plicata, indicating highly conserved innate immune mechanisms in the chordates' phylogeny.

MICROSCOPY RESEARCH AND TECHNIQUE (2022)

Article Anatomy & Morphology

Palynomorphological diversity among the Asteraceous honeybee flora: An aid to the correct taxonomic identification using multiple microscopic techniques

Nabila, Mushtaq Ahmad, Muhammad Zafar, Saraj Bahadur, Shazia Sultana, Sehrish Taj, Ferhat Celep, Salman Majeed, Rozina

Summary: This study characterized the palynological morphology of melliferous species of family Asteraceae and identified different pollen types and surface patterns, which can be used to recognize the most commonly visited bee floral species by honeybees.

MICROSCOPY RESEARCH AND TECHNIQUE (2022)

Article Anatomy & Morphology

Frontal and parietal EEG alpha asymmetry: a large-scale investigation of short-term reliability on distinct EEG systems

Dorothea Metzen, Erhan Genc, Stephan Getzmann, Mauro F. Larra, Edmund Wascher, Sebastian Ocklenburg

Summary: The study presents the first large-scale short-term reliability study of frontal and parietal EEG resting-state alpha asymmetry, showing good reliability of alpha power and alpha asymmetry on both systems for electrode pairs. It also found that alpha power asymmetry reliability is higher in the eyes-closed condition than in the eyes-open condition, and that the frontomedial electrode pair showed weaker reliability compared to the frontolateral and parietal electrode pairs.

BRAIN STRUCTURE & FUNCTION (2022)

Review Anatomy & Morphology

Extended reality anatomy undergraduate teaching: A literature review on an alternative method of learning

Lucy Taylor, Tamsin Dyer, Mohammed Al-Azzawi, Christian Smith, Obi Nzeako, Zameer Shah

Summary: The study found that augmented reality (AR) and virtual reality (VR) have high rates of satisfaction and acceptability as supplementary teaching aids for undergraduate students in anatomy education. AR was found to be more effective than VR, but VR is more expensive. Larger and long-term studies are needed to evaluate the true effectiveness and clinical relevance of these technologies.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER (2022)

Article Anatomy & Morphology

A survey study on distance anatomy education: challenges unique to anatomy

Abdullah Ortadeveci, Merve Nur Ermez, Semih Oz, Hilmi Ozden

Summary: According to the results, students found the efficiency of distance anatomy education (DAE), especially in terms of practical lessons, to be lower than traditional anatomy education (TAE). Future studies should aim to develop a new syllabus for DAE to make it a powerful alternative to TAE.

SURGICAL AND RADIOLOGIC ANATOMY (2022)

Article Anatomy & Morphology

Prognostic and Clinicopathologic Associations of LAG-3 Expression in Triple-negative Breast Cancer

Elisabeth S. Stovgaard, Iben Kumler, Kamille List-jensen, Anne Roslind, Ib J. Christensen, Estrid Hogdall, Dorte Nielsen, Eva Balslev

Summary: The immune checkpoint molecule LAG-3 is being investigated as a potential target for immunotherapy in TNBC, and its expression is associated with improved survival. Coexpression of LAG-3 and PD-L1 does not provide additional benefits in terms of survival.

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY (2022)

Review Anatomy & Morphology

Small junction, big problems: Neuromuscular junction pathology in mouse models of amyotrophic lateral sclerosis (ALS)

Abrar Alhindi, Ines Boehm, Helena Chaytow

Summary: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with a heterogeneous clinical and genetic phenotype, and mouse models have shown variable disease progression at the neuromuscular junction (NMJ). Models with SOD1, TARDBP, and FUS mutations exhibit early NMJ dysfunction as a common factor, while C9ORF72 models do not follow the same pattern. Further study into the timing of NMJ pathology in newer ALS mouse models will confirm its pivotal role in ALS pathogenesis.

JOURNAL OF ANATOMY (2022)

Article Anatomy & Morphology

Online lessons of human anatomy: Experiences during the COVID-19 pandemic

Daniela Zarcone, Daniele Saverino

Summary: The COVID-19 pandemic has led to the migration of human anatomy lessons to virtual platforms, presenting challenges for educators. However, distance learning has been found to be effective and positively perceived by most students.

CLINICAL ANATOMY (2022)

Article Anatomy & Morphology

Luteolin inhibits viability, migration, angiogenesis and invasion of non-small cell lung cancer vascular endothelial cells via miR-133a-3p/purine rich element binding protein B-mediated MAPK and PI3K/Akt signaling pathways

Jie Pan, Xiaoping Cai, Xiao Zheng, Xiaoyu Zhu, Jihong Feng, Xiaoqiu Wang

Summary: Luteolin inhibits the migration and invasion of NSCLC-VECs through the miR-133a-3p/PURB-mediated MAPK and PI3K/Akt pathways.

TISSUE & CELL (2022)

Review Anatomy & Morphology

OVOL1/2: Drivers of Epithelial Differentiation in Development, Disease, and Reprogramming

Kritika Saxena, Syamanthak Srikrishnan, Toni Celia-Terrassa, Mohit Kumar Jolly

Summary: OVOL proteins play critical roles in epithelial lineage determination and differentiation during embryonic development, cancer progression, and cellular reprogramming.

CELLS TISSUES ORGANS (2022)

Review Anatomy & Morphology

Measuring and Modelling the Epithelial- Mesenchymal Hybrid State in Cancer: Clinical Implications

Mohit Kumar Jolly, Ryan J. Murphy, Sugandha Bhatia, Holly J. Whitfield, Andrew Redfern, Melissa J. Davis, Erik W. Thompson

Summary: The epithelial-mesenchymal (E/M) hybrid state plays a significant role in cancer progression, facilitated by epithelial mesenchymal plasticity (EMP). Modeling and validation studies have shown the stabilised E/M hybrid states across the spectrum of EMP, along with computational approaches for characterising EMP phenotypes.

CELLS TISSUES ORGANS (2022)

Article Anatomy & Morphology

Paleoneurology of Baurusuchus (Crocodyliformes: Baurusuchidae), ontogenetic variation, brain size, and sensorial implications

Marcos V. Dumont Jr, Rodrigo M. Santucci, Marco Brandalise de Andrade, Carlos Eduardo Maia de Oliveira

Summary: With the development of computed tomography, our knowledge on crocodyliform paleoneurology has improved significantly. In this study, we reconstructed brain endocasts for multiple fossil specimens of the same crocodyliform taxon for the first time. Our findings show that the relative brain size of Baurusuchus is small compared to modern crocodilians, but its sensorial abilities are similar. Unlike its modern relatives, Baurusuchus' hypothesized alert head posture is compatible with a terrestrial habit.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2022)

Article Anatomy & Morphology

Osteology and relationships of Revueltosaurus callenderi (Archosauria: Suchia) from the Upper Triassic (Norian) Chinle Formation of Petrified Forest National Park, Arizona, United States

William G. Parker, Sterling J. Nesbitt, Randall B. Irmis, Jeffrey W. Martz, Adam D. Marsh, Matthew A. Brown, Michelle R. Stocker, Sarah Werning

Summary: A study describes the early-diverging pseudosuchian Revueltosaurus callenderi from Arizona, based on 12 skeletons found in a bonebed, which possess unique features that help clarify its relationships within Pseudosuchia. Histological analysis of the femur indicates that the individuals were not young juveniles and had slow growth rate.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2022)

Article Anatomy & Morphology

The inclusion of leukocytes into platelet rich plasma reduces scaffold stability and hinders extracellular matrix remodelling.

Eduardo Anitua, Mar Zalduendo, Maria Troya, Roberto Tierno, Mohammad H. Alkhraisat

Summary: The study evaluated the effects of leukocytes on the stability and cellular responses in PRGF scaffolds. Different cell phenotypes impacted the fibrinolysis and matrix deposition process in the clots. Overall, inclusion of leukocytes in PRGF scaffolds reduced stability, cell proliferation, and slowed down cell remodeling.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER (2022)

Article Anatomy & Morphology

The human masseter muscle revisited: First description of its coronoid part

Szilvia E. Mezey, Magdalena Mueller-Gerbl, Mireille Toranelli, Jens Christoph Turp

Summary: This study investigated the anatomy of the masseter muscle and identified a distinct third layer, named the coronoid part of the masseter. The arrangement of muscle fibers suggests its involvement in stabilizing the mandible.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER (2022)

Review Anatomy & Morphology

The role of LTBPs in TGF beta signaling

Daniel Rifkin, Nalani Sachan, Karan Singh, Elyse Sauber, George Tellides, Francesco Ramirez

Summary: This review focuses on the involvement of LTBP in the activity of TGFB, discussing their biology and cell function, summarizing the physiological consequences of LTBP loss in humans and mice, and addressing unanswered questions related to LTBP function.

DEVELOPMENTAL DYNAMICS (2022)

Article Anatomy & Morphology

The role of the angular gyrus in semantic cognition: a synthesis of five functional neuroimaging studies

Philipp Kuhnke, Curtiss A. Chapman, Vincent K. M. Cheung, Sabrina Turker, Astrid Graessner, Sandra Martin, Kathleen A. Williams, Gesa Hartwigsen

Summary: Semantic knowledge plays a central role in human cognition, and the angular gyrus (AG) is believed to be a key brain region for semantic processing. However, the role of the AG in semantic processing is controversial. This study analyzed fMRI data from multiple studies to investigate the response profiles of the AG during semantic processing. The findings suggest that the AG is involved in both general task-difficulty-related processes and specific semantic processes. The left AG acts as a convergence zone, binding different semantic features associated with the same concept to facilitate efficient access to relevant features.

BRAIN STRUCTURE & FUNCTION (2022)

Article Anatomy & Morphology

Microscopic segmentation and classification of COVID-19 infection with ensemble convolutional neural network

Javeria Amin, Muhammad Almas Anjum, Muhammad Sharif, Amjad Rehman, Tanzila Saba, Rida Zahra

Summary: A three-phase model is proposed for COVID-19 detection in CT images, achieving a global segmentation accuracy of 0.96 and 0.97 for classification through denoising, segmentation, and deep learning processes.

MICROSCOPY RESEARCH AND TECHNIQUE (2022)

Article Anatomy & Morphology

Bone marrow mesenchymal stem cell derived exosomal miR-455-5p protects against spinal cord ischemia reperfusion injury

Bing Liu, Wenjun Zheng, Li Dai, Shengjie Fu, Enyi Shi

Summary: The therapeutic effect of exosome-delivered miR-455-5p on spinal cord ischemia reperfusion injury was investigated in this study. Results showed that exosomal miR-455-5p enhanced recovery of hind-limb function, reduced histopathological abnormalities, decreased apoptosis, and activated autophagy in neurons after SCIR. Additionally, miR-455-5p was found to target Nogo-A and modulate its expression in the spinal cord of SCIR rats.

TISSUE & CELL (2022)

Article Anatomy & Morphology

Anatomy education for medical students in a virtual reality workspace: A pilot study

Kohga Nakai, Satoshi Terada, Ayaka Takahara, Dany Hage, R. Shane Tubbs, Joe Iwanaga

Summary: The COVID-19 pandemic forced medical schools to adjust their curricula online, including anatomy courses. This study explores the use of a virtual reality workspace for anatomy lectures and its advantages in improving student understanding of anatomy. Feedback from medical students participating in the VR workspace showed benefits in accessing course material anytime and anywhere, as well as manipulating anatomical structures for a better learning experience.

CLINICAL ANATOMY (2022)