期刊
HAEMATOLOGICA
卷 103, 期 11, 页码 1772-1784出版社
FERRATA STORTI FOUNDATION
DOI: 10.3324/haematol.2018.189159
关键词
-
类别
资金
- Deutsche Krebshilfe [1095969, 111424]
- Foundation against Cancer
- Fonds National de la Recherche Scientifique
- Fonds d'Investissement de Recherche Scientifique (FIRS) du CHU de Liege
- NIHR Imperial Biomedical Research Centre
- Cancer Research UK Imperial Centre
The diagnosis of multiple myeloma can be challenging, even for experienced physicians, and requires close collaboration between numerous disciplines (orthopedics, radiology, nuclear medicine, radiation therapy, hematology and oncology) before the final diagnosis of myeloma is made. The definition of multiple myeloma is based on the presence of clinical, biochemical, histopathological, and radiological markers of disease. Specific tests are needed both at presentation and during follow-up in order to reach the correct diagnosis and characterize the disease precisely. These tests can also serve prognostic purposes and are useful for follow-up of myeloma patients. Molecular analyses remain pivotal for defining high-risk myeloma and are used in updated patient stratifications, while minimal residual disease assessment via flow cytometry, molecular techniques and radiological approaches provides additional prognostic information on patients' long-term outcome. This pivotal information will guide our future treatment decisions in forthcoming clinical trials. The European Myeloma Network group updated their guidelines on different diagnostic recommendations, which should be of value to enable appropriate use of the recommendations both at diagnosis and during follow-up.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据