期刊
GYNECOLOGICAL ENDOCRINOLOGY
卷 30, 期 1, 页码 34-37出版社
INFORMA HEALTHCARE
DOI: 10.3109/09513590.2013.848425
关键词
Abortion; diabetes; endometriosis; fetal growth; hypertension; preeclampsia; pregnancy; preterm birth
资金
- FRQS (Fonds de recherche du Quebec - Sante)
The aim of this study was to provide a temporal-spatial reference of adverse pregnancy outcomes (APO) and examine whether endometriosis promotes APO in the same population. Among the 31 068 women who had a pregnancy between 1997 and 2008 in Eastern Townships of Canada, 6749 (21.7%) had APO. These APO increased significantly with maternal age and over time (r(2)=0.522, p=0.008); and were dominated by preterm birth (9.3%), pregnancy-induced hypertension (8.3%) including gestational hypertension (6.5%), low birth weight (6.3%), gestational diabetes (3.4%), pregnancy loss (2.2%) including spontaneous abortion (1.5%) and stillbirth (0.6%), intrauterine growth restriction (2.1%) and preeclampsia (1.8%). Among the 31 068 pregnancies, 784 (2.5%) had endometriosis and 183 (23.3%) had both endometriosis and APO. Endometriosis has been shown to increase the incidence of fetal loss (OR =2.03; 95% Cl =1.42-2.90, p< 0.0001), including spontaneous abortion (OR =1.89; 95% CI =1.23-2.93, p=0.005) and stillbirth (OR =2.29; 95% CI =1.24-5.22, p = 0.012). This study provides a temporal-spatial reference on APO, which is a valuable tool for monitoring, comparing and correcting. It is also the first study to highlight an impact of endometriosis on the incidence of spontaneous abortion and stillbirth.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据