期刊
GYNECOLOGICAL ENDOCRINOLOGY
卷 29, 期 7, 页码 666-669出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/09513590.2013.798273
关键词
Humans; in vitro fertilization; intracytoplasmic sperm injection; placenta; placental index; pregnancy-related hypertensive disorders; small for gestational age fetus
Introduction: Our aim was to state the correlation between placental index and pregnancy outcomes or in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) pregnancies. Materials and methods: We included in this retrospective study all singleton births in a third level clinic during the period 2001-2011 (n = 18 386). We divided placental index into quartiles and analyzed the differences between the groups in term of pregnancy outcomes. Then, we estimated crude and adjusted odds ratios (ORs) for placental index over the third centile of the distribution to correlate with pregnancy outcomes. We also analyzed the correlation between IVF/ICSI conceived pregnancies and placental index. Results: Poor pregnancy outcomes were overrepresented in the highest quartile of placental index distribution. Thus, placental index was higher in pregnancies characterized by pregnancy-related hypertensive disorders (PRHDs), small for gestational age infants, newborn needing cardiopulmonary resuscitation or hospitalization in neonatal intensive care unit. These findings were independent of maternal age, length of gestation at delivery, IVF/ICSI conception and ethnicity. For IVF/ICSI pregnancies, the OR for being over the third quartile of placental index distribution was 2.01 (CI. 95 1.40-2.90) after adjustment for maternal age, length of gestation, ethnicity, birth weight, parity, fetal sex, alteration of glucose metabolism in pregnancy and PRHDs. Conclusions: We found a high placental index among pregnancies characterized by poor outcomes and conceived by IVF/ICSI.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据