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Victoria Fox et al.
STEM CELLS (2008)
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Transforming growth factor alpha acts as a gliatrophin for mouse and human astrocytes
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Notch signaling is inactive hut inducible in human embryonic stem cells
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The role of PI3K/AKT, MAPK/ERK and NFκβ signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis
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Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression
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Transcriptional profiling of the developmentally important signalling pathways in human embryonic stem cells
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Green tea catechin enhances osteogenesis in a bone marrow mesenchymal stem cell line
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OSTEOPOROSIS INTERNATIONAL (2005)
Hypoxia requires Notch signaling to maintain the undifferentiated cell state
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Regulation of the Notch target gene Hes-1 by TGFα induced Ras/MAPK signaling in human neuroblastoma cells
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Effects of branched-chain amino acids on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes
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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
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BLOOD (2004)
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Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling
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Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
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EXPERIMENTAL CELL RESEARCH (2003)
Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85α
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Expression of Wnt and Notch pathway genes in a pluripotent human embryonal carcinoma cell line and embryonic stem cells
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APMIS (2003)
Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells
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ONCOGENE (2002)
Activation of the TGFα autocrine loop is downstream of IGF-1 receptor activation during mitogenesis in growth factor dependent human colon carcinoma cells
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ONCOGENE (2002)
Notch signaling: From the outside in
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DEVELOPMENTAL BIOLOGY (2000)
Requirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1
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JOURNAL OF MOLECULAR NEUROSCIENCE (2000)
Ras pathway signals are required for notch-mediated oncogenesis
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ONCOGENE (2000)
L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid β-protein precursor γ-secretase activity
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