期刊
GREEN CHEMISTRY
卷 14, 期 5, 页码 1502-1506出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2gc35258c
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资金
- National Natural Science Foundation of China [21072042, 20872025]
- Nature Science Foundation of Hebei Province [B2011205031]
Low melting mixture of maltose-dimethylurea (DMU)-NH4Cl was found to be an inexpensive, non-toxic, easily biodegradable and effective reaction medium in the catalyst-free synthesis of quinazoline derivatives. This simple and efficient method furnished the corresponding quinazolines in high yields via one-pot three-component reaction of 2-aminoaryl ketones, aldehyde, and ammonium acetate under aerobic oxidation conditions.
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