4.8 Article

Highly efficient synthesis of phosphatidylserine in the eco-friendly solvent γ-valerolactone

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GREEN CHEMISTRY
卷 14, 期 6, 页码 1581-1583

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c2gc35092k

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  1. National Natural Science Foundation of China [21102027]
  2. Central Public-interest Scientific Institution Basal Research Fund [ZX1102]

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gamma-Valerolactone has recently been described as an excellent candidate for a green solvent which is available naturally. Herein, it was used as the reaction medium in biocatalysis for the first time. Our results indicated that a 95% yield of phosphatidylserine could be achieved. This work is a proof-of-concept, opening up the use of gamma-valerolactone in biotransformations.

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