期刊
GREEN CHEMISTRY
卷 14, 期 5, 页码 1471-1474出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2gc35078e
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资金
- Novartis-MIT Center for Continuous Manufacturing
A practical and economical protocol has been developed for the direct oxidative amidation of aromatic aldehydes with secondary amines to synthesize amides in a single operation under mild conditions within 15-40 min. The utilization of aqueous hydrogen peroxide affords a clean synthetic route. No catalysts or promoting reagents are required.
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