期刊
GREEN CHEMISTRY
卷 11, 期 8, 页码 1201-1208出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b904044g
关键词
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资金
- National Natural Science Foundation of China [20721003, 20872153]
- International Collaboration Projects [2007DFB30370, 20720102040]
- 863 Hi-Tech Program of China [2006AA020602]
Using [Au(PPh3)]Cl/Ag2CO3-catalyzed 5-endo-dig cyclization in water under microwave irradiation, we developed a fast and green route to prepare indole-1-carboxamides from N'-substituted N-(2-alkynylphenyl)ureas. The described method is tolerant to a variety of functional groups, including N'-aryl, alkyl, heterocyclic, various N-(substituted-2-ethynylphenyl) and N-(2-ethynylpyridin-3-yl) ureas and affords moderate to high yields of the desired products.
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