期刊
GRASAS Y ACEITES
卷 60, 期 4, 页码 405-412出版社
CONSEJO SUPERIOR INVESTIGACIONES CIENTIFICAS-CSIC
DOI: 10.3989/gya.010109
关键词
Antioxidant activity; Chelating ability; DPPH; Essential oil; Ferula assafoetida
资金
- Mazandaran University of Medical Sciences
- Islamic Azad University of Qaemshahr
The antioxidant activity of the aerial parts of Ferula assafoetida was determined by employing various in vitro assay systems. IC50, for DPPH radical-scavenging activity was 380 +/- 12 mg ml(-1). The extracts showed good nitric oxide-scavenging activity (IC50, was 270 +/- 3) and Fe2+ chelating ability (IC50 was 0.57 +/- 0.02 mg ml(-1)). The peroxidation inhibition (antioxidant activity) of the extracts exhibited values from 82% (at 24 hrs) and 88% (at 72 hrs). The extract exhibited a fairy weak reducing power at 25-800 mu g ml(-1) of extracts which was not comparable with Vitamin C (p < 0.001). The tested extracts exhibited very low antioxidant activity. In addition, the chemical composition of the essential oil of the aerial parts was determined. The major compounds were phenol, 2-methyl-5-(1-methyl ethyl) (18.2%), alpha-Bisabolol (10.4%) and Arsine triethyl (8.7%). Total phenol compounds, as determined by the Folin Ciocalteu method, were 94.8 +/- 5.9 mg gallic acid equivalent/g of extract powder and the total flavonoid content (by AlCl3 method) was 90.9 +/- 6.3 mg quercetin equivalent/g of extract powder.
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