期刊
JOURNAL OF VIROLOGY
卷 89, 期 11, 页码 6131-6135出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.00661-15
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资金
- CEIRS (NIAID/NIH) [HHSN 266200700010C]
- Dutch Scientific Research (NWO) [40-00812-98-13066]
- European Union FP7 project Silver [260644]
- European Union FP7 project ANTIGONE [278976]
The ability of Middle East respiratory syndrome coronavirus (MERS-CoV) to infect small animal species may be restricted given the fact that mice, ferrets, and hamsters were shown to resist MERS-CoV infection. We inoculated rabbits with MERS-CoV. Although virus was detected in the lungs, neither significant histopathological changes nor clinical symptoms were observed. Infectious virus, however, was excreted from the upper respiratory tract, indicating a potential route of MERS-CoV transmission in some animal species.
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