期刊
GENOME BIOLOGY AND EVOLUTION
卷 6, 期 5, 页码 1234-1237出版社
OXFORD UNIV PRESS
DOI: 10.1093/gbe/evu098
关键词
causal role; selected effect; ENCODE project; functional genomics
资金
- Canadian Institutes for Health Research
- Natural Sciences and Engineering Research Council of Canada
Much confusion in genome biology results from conflation of possible meanings of the word function. We suggest that, in this connection, attention should be paid to evolutionary biologists and philosophers who have previously dealt with this problem. We need only decide that although all genomic structures have effects, only some of them should be said to have functions. Although it will very often be difficult or impossible to establish function (strictly defined), it should not automatically be assumed. We enjoin genomicists in particular to pay greater attention to parsing biological effects.
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