期刊
GENETICS IN MEDICINE
卷 16, 期 3, 页码 207-216出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/gim.2013.125
关键词
carrier screening; cystic fibrosis; literature review; population based; psychosocial
资金
- NHMRC Capacity Building Grant in Population Health
- Victorian Government's Operational Infrastructure Support Program
Cystic fibrosis is the most common severe autosomal recessive disease, with a prevalence of 1 in 2,500-3,500 live births and a carrier frequency of 1 in 25 among Northern Europeans. Population-based carrier screening for cystic fibrosis has been possible since CFTR, the disease-causing gene, was identified in 1989. This review provides a systematic evaluation of the literature from the past 23 years on population-based carrier screening for cystic fibrosis, focusing on the following: uptake of testing; how to offer screening; attitudes, opinions, and knowledge; factors influencing decision making; and follow,up after screening. Recommendations are given for the implementation and evaluation of future carrier-screening programs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据