期刊
GENETICS
卷 195, 期 1, 页码 289-+出版社
GENETICS SOC AM
DOI: 10.1534/genetics.113.153825
关键词
-
资金
- National Natural Science Foundation of China, NSFC [31171278, 31271542]
- 973 program [2009CB918702, 2012CB825504]
- NSFC [31071087, 31271573]
- National Cancer Institute
We report that Cas9/gRNA mediates efficient genetic modifications in Drosophila. Through targeting seven loci, we achieved a germline efficiency of up to 100%. Genes in both heterochromatin and euchromatin can be modified efficiently. Thus the Cas9/gRNA system is an attractive tool for rapid disruption of essentially any gene in Drosophila.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据