期刊
GENETICS
卷 191, 期 4, 页码 1073-1105出版社
GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.111.137851
关键词
-
资金
- National Institutes of Health [RO1 GM43265, RO1 GM026938]
- Canadian Institutes for Health Research [MOP97874, MOP110982]
The mechanisms that maintain the stability of chromosome ends have broad impact on genome integrity in all eukaryotes. Budding yeast is a premier organism for telomere studies. Many fundamental concepts of telomere and telomerase function were first established in yeast and then extended to other organisms. We present a comprehensive review of yeast telomere biology that covers capping, replication, recombination, and transcription. We think of it as yeast telomeres-soup to nuts.
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