期刊
GENETICS
卷 186, 期 1, 页码 427-430出版社
GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.110.119230
关键词
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资金
- Universite de Strasbourg
- Centre National de la Recherche Scientifique (CNRS)
- Fondation pour la Recherche Medicale
Mutant screens have proven powerful for genetic dissection of a myriad of biological processes, but subsequent identification and isolation of the causative mutations are usually complex and time consuming. We have made the process easier by establishing a novel strategy that employs whole-genome sequencing to simultaneously map and identify mutations without the need for any prior genetic mapping.
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