期刊
GENETICS
卷 179, 期 1, 页码 317-322出版社
GENETICS
DOI: 10.1534/genetics.108.087650
关键词
-
资金
- NICHD NIH HHS [5R01HD18055, R01 HD018055] Funding Source: Medline
Di- and triniethylation of histone H4 lysine20 (H4K20) are thought to play an important role in controlling gene expression in vertebrates and in Drosophila. By inducing a null mutation in Drosophila Suv4-20, we show that it encodes the histone H4 lysine20 di- and trimethyltransferase. In Suv4-20 mutants, the H4K20 di- and trimethyl marks are strongly reduced or absent, and the monomethyl mark is significantly increased. We find that even with this biochemical function, Suv4-20 is not required for Survival and does not Control position-effect variegation (PEV).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据