4.7 Article

Spindly attachments

期刊

GENES & DEVELOPMENT
卷 22, 期 17, 页码 2302-2307

出版社

COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/gad.1719208

关键词

centromere; aneuploidy; mitosis; kinetochore; microtubule; spindle; chromosome

资金

  1. Association for International Cancer Resarch (AICR)
  2. Telethon Foundation
  3. EU [FP6]
  4. Italian Association for Cancer Research (AIRC)
  5. Fondo di Investimento per la Ricerca di Base (FIRB)
  6. Italian Ministry of Health
  7. Nando Peretti Foundation

向作者/读者索取更多资源

The attachment of chromosomes to spindle microtubules during mitosis is a delicate and intricate process on which eukaryotic cells critically depend to maintain their ploidy. In this issue of Genes & Development, Gassmann and colleagues ( pp. 2385-2399) present an analysis of the recently discovered Spindly/SPDL-1 protein that casts new lights onto the attachment process and the way it relates to the control of cell cycle progression.

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