期刊
GENERAL PHYSIOLOGY AND BIOPHYSICS
卷 29, 期 1, 页码 3-11出版社
GENERAL PHYSIOL AND BIOPHYSICS
DOI: 10.4149/gpb_2010_01_3
关键词
Mitochondria; Complex I; Respiratory chain; Apoptosis
资金
- Ministry of Education of Slovak Republic [VEGA 1/4255/07, VVCE 0064-07]
The mitochondrial respiratory chain consists of five multi-subunit complexes embedded in the inner mitochondrial membrane. Complex 1 is the largest and most complicated proton pump of the respiratory chain encoded by both the mitochondrial and nuclear genomes. In this minireview, attention is given to recent knowledge on the structure, catalytic properties, supramolecular organisation of complex I and its possible role in the triggering of apoptosis.
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